RCSB PDB: Search

Warning You are using a web browser that we do not support. Our website will not work properly. Please update to a newer version or download a new web browser, such as Chrome or Firefox.

Help

Help

RCSB PDB

Deposit
- PDBx/mmCIF file
- pdb_extract
- SF-Tool
- Ligand Expo
- MAXIT
- Validation Server
- Validation API
- Information for Journals
- Validation Task Forces
- wwPDB OneDep System
- PDB-IHM
Search
Visualize
Analyze
Download
Learn
- Training Courses
- Guide to PDB Data
- Molecule of the Month
- Educational Resources
- Curricula
- Browse
- News
- SciArt Galleries
- Irving Geis
- David Goodsell
About
Careers
COVID-19

232,829 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

	Include CSM
Advanced Search \| Browse Annotations		Help

Search
Query History
Browse Annotations
MyPDB

QUERY: Gene Name = "TLN1"

MyPDB Login

Search API

Advanced Search Query Builder

Help

Full Text

Structure Attributes

Help

NOT

Count

Add Subquery

Chemical Attributes

Sequence Similarity

Sequence Motif

Structure Similarity

Structure Motif

Chemical Similarity

Return

grouped by

Include Computed Structure Models (CSM)

Count

Clear

Search Summary

This query matches 57 Structures.

Refinements

Structure Determination Methodology

experimental (57)

Scientific Name of Source Organism

	Mus musculus (48)
	Homo sapiens (11)
	Gallus gallus (10)
	Oryctolagus cuniculus (1)
	Shigella flexneri (1)

Taxonomy

	Eukaryota (57)
	Eukaryota (eukaryotes) (10)
	Bacteria (1)

Experimental Method

	X-RAY DIFFRACTION (33)
	SOLUTION NMR (18)
	ELECTRON MICROSCOPY (6)

Polymer Entity Type

Protein (57)

Refinement Resolution (Å)

	1.5 - 2.0 (9)
	2.0 - 2.5 (11)
	2.5 - 3.0 (13)
	3.0 - 3.5 (3)
	3.5 - 4.0 (1)
	> 4.5 (2)

Release Date

	2000 - 2004 (4)
	2005 - 2009 (17)
	2010 - 2014 (13)
	2015 - 2019 (6)
	2020 - 2024 (16)
	2025 - 2029 (1)

Enzyme Classification Name

	Transferases (5)
	Hydrolases (2)

Symmetry Type

	Asymmetric (53)
	Cyclic (6)
	Dihedral (1)

SCOP Classification

	All alpha proteins (10)
	All beta proteins (4)
	Artifacts (3)
	Alpha and beta proteins (a/b) (1)

AllSelected

1 to 25 of 57 Structures

Page 1 of 3

Sort by

Explore in 3D

1SJ7	Download File View File

Crystal Structure of Talin Rod 482-655

Papagrigoriou, E., Gingras, A.R., Barsukov, I.L., Critchley, D.R., Emsley, J.

(2004) EMBO J 23: 2942-2951

Released	2004-08-24
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Mus musculus
Macromolecule	Talin 1 (protein)
Unique Ligands	PT

Explore in 3D

1SJ8	Download File View File

Solution Structure of the R1R2 Domains of Talin

Papagrigoriou, E., Gingras, A.R., Barsukov, I.L., Critchley, D.R., Emsley, J.

(2004) EMBO J 23: 2942-2951

Released	2004-08-24
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Mus musculus
Macromolecule	Talin 1 (protein)

Explore in 3D

1SYQ	Download File View File

Human vinculin head domain VH1, residues 1-258, in complex with human talin's vinculin binding site 1, residues 607-636

Izard, T., Vonrhein, C.

(2004) J Biological Chem 279: 27667-27678

Released	2004-07-20
Method	X-RAY DIFFRACTION 2.42 Å
Organisms	Homo sapiens
Macromolecule	Talin 1 (protein) vinculin isoform VCL (protein)

Explore in 3D

1T01	Download File View File

Vinculin complexed with the VBS1 helix from talin

Papagrigoriou, E., Gingras, A.R., Barsukov, I.L., Critchley, D.R., Emsley, J.

(2004) EMBO J 23: 2942-2951

Released	2004-08-24
Method	X-RAY DIFFRACTION 2.06 Å
Organisms	Gallus gallus Mus musculus
Macromolecule	Talin 1 (protein) unnamed protein product (protein)

Explore in 3D

1U6H	Download File View File

Vinculin head (0-258) in complex with the talin vinculin binding site 2 (849-879)

Fillingham, I., Gingras, A.R., Papagrigoriou, E., Patel, B., Emsley, J., Roberts, G.C.K., Critchley, D.R., Barsukov, I.L.

(2005) Structure 13: 65-74

Released	2005-01-18
Method	X-RAY DIFFRACTION 2.38 Å
Organisms	Gallus gallus
Macromolecule	Talin (protein) Vinculin (protein)

Explore in 3D

1XWJ	Download File View File

Vinculin head (1-258) in complex with the talin vinculin binding site 3 (1945-1969)

Gingras, A.R., Papagrigoriou, E., Barsukov, I.L., Critchley, D.R., Emsley, J.

(2006) Biochemistry 45: 1805-1817

Released	2005-10-11
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Gallus gallus
Macromolecule	Talin (protein) Vinculin (protein)

Explore in 3D

1Y19	Download File View File

Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions

de Pereda, J.M., Wegener, K., Santelli, E., Bate, N., Ginsberg, M.H., Critchley, D.R., Campbell, I.D., Liddington, R.C.

(2005) J Biological Chem 280: 8381-8386

Released	2005-01-04
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Mus musculus
Macromolecule	Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma (protein) Talin 1 (protein)

Explore in 3D

1ZVZ	Download File View File

Vinculin Head (0-258) in Complex with the Talin Rod Residue 820-844

Gingras, A.R., Ziegler, W.H., Barsukov, I.L., Roberts, G.C., Critchley, D.R., Emsley, J.

(2005) J Biological Chem 280: 37217-37224

Released	2005-09-20
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Gallus gallus
Macromolecule	Talin 1 (protein) Vinculin (protein)

Explore in 3D

1ZW2	Download File View File

Vinculin Head (0-258) in Complex with the Talin Rod residues 2345-2369

Gingras, A.R., Ziegler, W.H., Barsukov, I.L., Roberts, G.C., Critchley, D.R., Emsley, J.

(2005) J Biological Chem 280: 37217-37224

Released	2005-09-20
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Gallus gallus
Macromolecule	Vinculin (protein) talin (protein)

Explore in 3D

1ZW3	Download File View File

Vinculin Head (0-258) in Complex with the Talin Rod residues 1630-1652

Gingras, A.R., Ziegler, W.H., Barsukov, I.L., Roberts, G.C., Critchley, D.R., Emsley, J.

(2005) J Biological Chem 280: 37217-37224

Released	2005-09-20
Method	X-RAY DIFFRACTION 3.3 Å
Organisms	Gallus gallus Mus musculus
Macromolecule	Talin 1 (protein) Vinculin (protein)

Explore in 3D

2B0H	Download File View File

Solution structure of VBS3 fragment of talin

Gingras, A.R., Vogel, K.P., Steinhoff, H.J., Ziegler, W.H., Patel, B., Emsley, J., Critchley, D.R., Roberts, G.C., Barsukov, I.L.

(2006) Biochemistry 45: 1805-1817

Released	2006-01-17
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	Talin-1 (protein)

Explore in 3D

2G35	Download File View File

NMR structure of talin-PTB in complex with PIPKI

Kong, X., Wang, X., Misra, S., Qin, J.

(2006) J Mol Biology 359: 47-54

Released	2006-05-02
Method	SOLUTION NMR
Organisms	Homo sapiens Mus musculus
Macromolecule	Talin-1 (protein) peptide (protein)

Explore in 3D

2H7D	Download File View File

Solution structure of the talin F3 domain in complex with a chimeric beta3 integrin-PIP kinase peptide

Wegener, K.L.

(2007) Cell 128: 171-182

Released	2007-01-30
Method	SOLUTION NMR
Organisms	Gallus gallus Mus musculus
Macromolecule	Chimera of 24-mer peptide from Integrin beta-3 and 10-mer peptide from Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (protein) Talin-1 (protein)

Explore in 3D

2H7E	Download File View File

Solution structure of the talin F3 domain in complex with a chimeric beta3 integrin-PIP kinase peptide- minimized average structure

Wegener, K.L.

(2007) Cell 128: 171-182

Released	2007-01-30
Method	SOLUTION NMR
Organisms	Gallus gallus Mus musculus
Macromolecule	Chimera of 24-mer peptide from Integrin beta-3 and 10-mer peptide from Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (protein) Talin-1 (protein)

Explore in 3D

2HRJ	Download File View File

NMR solution structure of the F2 subdomain of talin

Liu, G., Arroyo, M.M., Zheng, J.

To be published

Released	2008-04-29
Method	SOLUTION NMR
Organisms	Gallus gallus
Macromolecule	Talin-1 (protein)

Explore in 3D

2JSW	Download File View File

Solution Structure of the R13 Domain of Talin

Goult, B.T., Gingras, A.R., Bate, N., Critchley, D.R.C., Barsukov, I.L.

(2007) EMBO J 27: 458-469

Released	2008-01-29
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	Talin-1 (protein)

Explore in 3D

2K00	Download File View File

Solution structure of the talin F3 in complex with layilin cytodomain

Wegener, K.L., Barsukov, I.L.

(2008) J Mol Biology 382: 112-126

Released	2008-09-09
Method	SOLUTION NMR
Organisms	Gallus gallus Mus musculus
Macromolecule	Layilin (protein) Talin-1 (protein)

Explore in 3D

2KBB	Download File View File

Solution Structure of the R9 Domain of Talin

Goult, B.T., Gingras, A.R., Bate, N., Critchley, D.R., Barsukov, I.L.

(2009) J Biological Chem 284: 15097-15106

Released	2009-03-17
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	Talin-1 (protein)

Explore in 3D

2KC1	Download File View File

NMR structure of the F0 domain (residues 0-85) of the talin ferm domain

Goult, B.T., Elliott, P.R., Roberts, G.C.K., Critchley, D.R., Barsukov, I.L.

(2010) EMBO J 29: 1069-1080

Released	2010-01-19
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	MKIAA1027 protein (protein)

Explore in 3D

2KC2	Download File View File

NMR structure of the F1 domain (residues 86-202) of the talin

Goult, B.T., Elliott, P.R., Roberts, G.C.K., Critchely, D.R., Barsukov, I.L.

(2010) EMBO J 29: 1069-1080

Released	2010-01-19
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	Talin-1 (protein)

Explore in 3D

2KGX	Download File View File

HADDOCK structure of the talin F3 domain in complex with talin 1655-1822

Goult, B.T., Gingras, A.R., Bate, N., Critchley, D.R., Barsukov, I.L.

(2009) J Biological Chem 284: 15097-15106

Released	2009-03-31
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	MKIAA1027 protein (protein) Talin-1 (protein)

Explore in 3D

2KMA	Download File View File

NMR structure of the F0F1 double domain (residues 1-202) of the talin ferm domain

Goult, B.T., Elliott, P.R., Bate, N., Roberts, G.C., Critchley, D.R., Barsukov, I.L.

(2010) EMBO J

Released	2010-03-02
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	Talin 1 (protein)

Explore in 3D

2KVP	Download File View File

Solution Structure of the R10 Domain of Talin

Goult, B.T., Gingras, A.R., Bate, N., Critchley, D.R., Barsukov, I.L., Roberts, G.C.

(2010) FEBS Lett 584: 2237-2241

Released	2010-05-05
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	Talin-1 (protein)

Explore in 3D

2L10	Download File View File

Solution Structure of the R6 Domain of Talin

Goult, B.T., Gingras, A.R., Bate, N., Roberts, G.C.K., Barsukov, I.L., Critchley, D.R.

(2013) J Biological Chem 288: 8238-8249

Released	2011-08-31
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	Talin-1 (protein)

Explore in 3D

2L7N	Download File View File

Solution Structure of the R5 Domain of Talin

Goult, B.T., Gingras, A.R., Bate, N., Barsukov, I.L., Roberts, G.C.K., Critchley, D.R.

(2013) J Biological Chem 288: 8238-8249

Released	2011-12-14
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	Talin-1 (protein)

1 to 25 of 57 Structures

Page 1 of 3

Sort by

About
About Us
Citing Us
Publications
Team
Careers
Usage & Privacy

Support
Contact Us
Help
Website FAQ
Glossary
Service Status

RCSB PDB is hosted by

RCSB PDB is a member of the

RCSB Partners
Nucleic Acid Knowledgebase

wwPDB Partners
RCSB PDB
PDBe
PDBj
BMRB
EMDB

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

Prepare Data

Validate Data

Deposit Data

Help and Resources

Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification