RCSB PDB: Search

AllSelected

5ZCS \| pdb_00005zcs	Download File View File

4.9 Angstrom Cryo-EM structure of human mTOR complex 2

Chen, X., Liu, M., Tian, Y., Wang, H., Wang, J., Xu, Y.

(2018) Cell Res 28: 518-528

Released	2018-03-21
Method	ELECTRON MICROSCOPY 4.9 Å
Organisms	Homo sapiens
Macromolecule	Rapamycin-insensitive companion of mTOR (protein) Serine/threonine-protein kinase mTOR (protein) Target of rapamycin complex 2 subunit MAPKAP1 (protein) Target of rapamycin complex subunit LST8 (protein)

Explore in 3D

6ZWM \| pdb_00006zwm	Download File View File

cryo-EM structure of human mTOR complex 2, overall refinement

Scaiola, A., Mangia, F., Imseng, S., Boehringer, D., Ban, N., Maier, T.

(2020) Sci Adv 6:

Released	2020-11-18
Method	ELECTRON MICROSCOPY 3.2 Å
Organisms	Homo sapiens
Macromolecule	Rapamycin-insensitive companion of mTOR (protein) Serine/threonine-protein kinase mTOR (protein) Target of rapamycin complex 2 subunit MAPKAP1 (protein) Target of rapamycin complex subunit LST8 (protein)
Unique Ligands	ACE, AGS, IHP, ZN

Explore in 3D

6ZWO \| pdb_00006zwo	Download File View File

cryo-EM structure of human mTOR complex 2, focused on one half

Scaiola, A., Mangia, F., Imseng, S., Boehringer, D., Ban, N., Maier, T.

(2020) Sci Adv 6:

Released	2020-11-18
Method	ELECTRON MICROSCOPY 3 Å
Organisms	Homo sapiens
Macromolecule	Rapamycin-insensitive companion of mTOR (protein) Serine/threonine-protein kinase mTOR (protein) Target of rapamycin complex 2 subunit MAPKAP1 (protein) Target of rapamycin complex subunit LST8 (protein)
Unique Ligands	ACE, AGS, IHP, ZN

Explore in 3D

7PE7 \| pdb_00007pe7	Download File View File

cryo-EM structure of DEPTOR bound to human mTOR complex 2, overall refinement

Waelchli, M., Maier, T.

(2021) Elife 10:

Released	2021-09-15
Method	ELECTRON MICROSCOPY 3.41 Å
Organisms	Homo sapiens
Macromolecule	DEP domain-containing mTOR-interacting protein (protein) Rapamycin-insensitive companion of mTOR (protein) Serine/threonine-protein kinase mTOR (protein) Target of rapamycin complex 2 subunit MAPKAP1 (protein) Target of rapamycin complex subunit LST8 (protein)
Unique Ligands	ACE, IHP, ZN

Explore in 3D

7PE8 \| pdb_00007pe8	Download File View File

cryo-EM structure of DEPTOR bound to human mTOR complex 2, focussed on one protomer

Waelchli, M., Maier, T.

(2021) Elife 10:

Released	2021-09-08
Method	ELECTRON MICROSCOPY 3.2 Å
Organisms	Homo sapiens
Macromolecule	DEP domain-containing mTOR-interacting protein (protein) Rapamycin-insensitive companion of mTOR (protein) Serine/threonine-protein kinase mTOR (protein) Target of rapamycin complex 2 subunit MAPKAP1 (protein) Target of rapamycin complex subunit LST8 (protein)
Unique Ligands	ACE, IHP, ZN

Explore in 3D

7PE9 \| pdb_00007pe9	Download File View File

cryo-EM structure of DEPTOR bound to human mTOR complex 2, DEPt-bound subset local refinement

Waelchli, M., Maier, T.

(2021) Elife 10:

Released	2021-09-08
Method	ELECTRON MICROSCOPY 3.7 Å
Organisms	Homo sapiens
Macromolecule	DEP domain-containing mTOR-interacting protein (protein) Rapamycin-insensitive companion of mTOR (protein) Serine/threonine-protein kinase mTOR (protein) Target of rapamycin complex 2 subunit MAPKAP1 (protein) Target of rapamycin complex subunit LST8 (protein)
Unique Ligands	ACE, IHP, ZN

Explore in 3D

7TZO \| pdb_00007tzo	Download File View File

The apo structure of human mTORC2 complex

Yu, Z., Chen, J., Pearce, D.

(2022) J Biological Chem 298: 102288-102288

Released	2023-01-11
Method	ELECTRON MICROSCOPY 3.28 Å
Organisms	Homo sapiens
Macromolecule	Rapamycin-insensitive companion of mTOR (protein) Serine/threonine-protein kinase mTOR (protein) Target of rapamycin complex 2 subunit MAPKAP1 (protein) Target of rapamycin complex subunit LST8 (protein)

5ZCS | pdb_00005zcs

4.9 Angstrom Cryo-EM structure of human mTOR complex 2

6ZWM | pdb_00006zwm

cryo-EM structure of human mTOR complex 2, overall refinement

6ZWO | pdb_00006zwo

cryo-EM structure of human mTOR complex 2, focused on one half

7PE7 | pdb_00007pe7

cryo-EM structure of DEPTOR bound to human mTOR complex 2, overall refinement

7PE8 | pdb_00007pe8

cryo-EM structure of DEPTOR bound to human mTOR complex 2, focussed on one protomer

7PE9 | pdb_00007pe9

cryo-EM structure of DEPTOR bound to human mTOR complex 2, DEPt-bound subset local refinement

7TZO | pdb_00007tzo

The apo structure of human mTORC2 complex

Prepare Data

Validate Data

Deposit Data

Help and Resources

Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

5ZCS | pdb_00005zcs

4.9 Angstrom Cryo-EM structure of human mTOR complex 2

6ZWM | pdb_00006zwm

cryo-EM structure of human mTOR complex 2, overall refinement

6ZWO | pdb_00006zwo

cryo-EM structure of human mTOR complex 2, focused on one half

7PE7 | pdb_00007pe7

cryo-EM structure of DEPTOR bound to human mTOR complex 2, overall refinement

7PE8 | pdb_00007pe8

cryo-EM structure of DEPTOR bound to human mTOR complex 2, focussed on one protomer

7PE9 | pdb_00007pe9

cryo-EM structure of DEPTOR bound to human mTOR complex 2, DEPt-bound subset local refinement

7TZO | pdb_00007tzo

The apo structure of human mTORC2 complex