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232,829 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Gene Name = "Kiaa1650"

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Search Summary

This query matches 5 Structures.

Refinements

Structure Determination Methodology

experimental (5)

Scientific Name of Source Organism

	Homo sapiens (3)
	Mus musculus (3)

Taxonomy

Eukaryota (5)

Experimental Method

	X-RAY DIFFRACTION (4)
	SOLUTION NMR (1)

Polymer Entity Type

Protein (5)

Refinement Resolution (Å)

	1.5 - 2.0 (1)
	2.0 - 2.5 (1)
	2.5 - 3.0 (1)
	3.0 - 3.5 (1)

Release Date

	2010 - 2014 (1)
	2015 - 2019 (3)
	2020 - 2024 (1)

Enzyme Classification Name

Hydrolases (3)

Symmetry Type

	Asymmetric (5)
	Cyclic (1)

SCOP Classification

	All beta proteins (2)
	Alpha and beta proteins (a/b) (2)
	Artifacts (1)

AllSelected

1 to 5 of 5 Structures

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Explore in 3D

3O5N	Download File View File

Tetrahydroquinoline carboxylates are potent inhibitors of the Shank PDZ domain, a putative target in autism disorders

Saupe, J., Roske, Y., Schillinger, C., Kamdem, N., Radetzki, S., Diehl, A., Oschkinat, H., Krause, G., Heinemann, U., Rademann, J.

(2011) ChemMedChem 6: 1411-1422

Released	2011-06-15
Method	X-RAY DIFFRACTION 1.83 Å
Organisms	Mus musculus
Macromolecule	SH3 and multiple ankyrin repeat domains protein 3 (protein)
Unique Ligands	BR0

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6CPK	Download File View File

Solution structure of SH3 domain from Shank3

Ishida, H., Vogel, H.J.

(2018) FEBS Lett 592: 2786-2797

Released	2018-08-15
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	SH3 and multiple ankyrin repeat domains protein 3 (protein)

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6KYH	Download File View File

Crystal structure of Shank3 NTD-ANK A42K mutant in complex with HRas

Cai, Q., Zhang, M.

(2020) Structure 28: 290

Released	2019-12-04
Method	X-RAY DIFFRACTION 3.3 Å
Organisms	Mus musculus
Macromolecule	GTPase HRas (protein) SH3 and multiple ankyrin repeat domains protein 3 (protein)
Unique Ligands	GNP, MG

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6KYK	Download File View File

Crystal structure of Shank3 NTD-ANK mutant in complex with Rap1

Cai, Q., Zhang, M.

(2020) Structure 28: 290

Released	2019-12-04
Method	X-RAY DIFFRACTION 2.82 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Ras-related protein Rap-1b (protein) SH3 and multiple ankyrin repeat domains protein 3 (protein)
Unique Ligands	GNP, MG

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7C7J	Download File View File

Crystal structure of SHANK3 SPN domain in complex with GTP-bound Rap1b(G12V,Q63E)

Xiao, L.X., Pan, L.F.

(2020) Chin J Chem 38: 1635-1641

Released	2021-05-05
Method	X-RAY DIFFRACTION 2.39 Å
Organisms	Homo sapiens
Macromolecule	Ras-related protein Rap-1b (protein) SH3 and multiple ankyrin repeat domains protein 3 (protein)
Unique Ligands	CA, GTP, MG