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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Gene Name = "ELAVL1"

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Search Summary

This query matches 10 Structures.

Refinements

Structure Determination Methodology

experimental (10)

Scientific Name of Source Organism

	Homo sapiens (10)
	synthetic construct (3)
	Escherichia coli K-12 (1)

Taxonomy

	Eukaryota (10)
	other sequences (3)
	Bacteria (1)

Experimental Method

	X-RAY DIFFRACTION (9)
	SOLUTION NMR (1)

Polymer Entity Type

	Protein (10)
	RNA (5)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (3)
	2.0 - 2.5 (4)
	2.5 - 3.0 (1)

Release Date

	2010 - 2014 (4)
	2015 - 2019 (6)

Symmetry Type

	Asymmetric (9)
	Cyclic (2)

SCOP Classification

	Alpha and beta proteins (a+b) (5)
	Artifacts (2)

AllSelected

1 to 10 of 10 Structures

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3HI9 \| pdb_00003hi9	Download File View File

The x-ray crystal structure of the first RNA recognition motif (RRM1) of the AU-rich element (ARE) binding protein HuR at 2.0 angstrom resolution

Benoit, R.M., Kallen, J.

(2010) J Mol Biology 397: 1231-1244

Released	2010-03-31
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	ELAV-like protein 1 (protein)

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4ED5 \| pdb_00004ed5	Download File View File

Crystal structure of the two N-terminal RRM domains of HuR complexed with RNA

Wang, H., Zeng, F., Liu, Q., Niu, L., Teng, M., Li, X.

(2013) Acta Crystallogr D Biol Crystallogr 69: 373-380

Released	2012-05-23
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	ELAV-like protein 1 (protein) 5'-R(AUPUPUPUPUPAPUPUPUP*U)-3' (nucleic acid)
Unique Ligands	EDO, GOL, M2M

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4EGL \| pdb_00004egl	Download File View File

Crystal structure of two tandem RNA recognition motifs of Human antigen R

Wang, H., Zeng, F., Liu, H., Teng, M., Li, X.

To be published

Released	2012-05-30
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	ELAV-like protein 1 (protein)
Unique Ligands	GOL, SO4

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4FXV \| pdb_00004fxv	Download File View File

Crystal structure of an ELAV-like protein 1 (ELAVL1) from Homo sapiens at 1.90 A resolution

Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology, Partnership for T-Cell Biology (TCELL)

To be published

Released	2012-10-03
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	ELAV-like protein 1 (protein)

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5SZW \| pdb_00005szw	Download File View File

NMR solution structure of the RRM1 domain of the post-transcriptional regulator HuR

Lixa, C., Mujo, A., Jendiroba, K.A., Almeida, F.C.L., Lima, L.M.T.R., Pinheiro, A.S.

(2018) J Biomol NMR 72: 179-192

Released	2017-09-06
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	ELAV-like protein 1 (protein)

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6G2K \| pdb_00006g2k	Download File View File

Structure of HuR RRM3 in complex with RNA (UUUUUU)

Pabis, M., Sattler, M.

(2019) Nucleic Acids Res 47: 1011-1029

Released	2018-10-31
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Homo sapiens synthetic construct
Macromolecule	ELAV-like protein 1 (protein) RNA (5'-R(PUPUPUPUPUPU)-3') (nucleic acid)
Unique Ligands	SO4

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6GC5 \| pdb_00006gc5	Download File View File

Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM

Ripin, N., Allain, F.H.

(2019) Proc Natl Acad Sci U S A 116: 2935-2944

Released	2019-01-30
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	ELAV-like protein 1 (protein) AU-rich RNA (nucleic acid)

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6GD1 \| pdb_00006gd1	Download File View File

Structure of HuR RRM3

Pabis, M., Sattler, M.

(2019) Nucleic Acids Res 47: 1011-1029

Released	2018-10-31
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Escherichia coli K-12 Homo sapiens
Macromolecule	Thioredoxin 1,ELAV-like protein 1 (protein)
Unique Ligands	NA

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6GD2 \| pdb_00006gd2	Download File View File

Structure of HuR RRM3 in complex with RNA

Pabis, M., Sattler, M.

(2019) Nucleic Acids Res 47: 1011-1029

Released	2018-10-31
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens synthetic construct
Macromolecule	ELAV-like protein 1 (protein) RNA (5'-R(PUPUPUPAPUPUP*U)-3') (nucleic acid)

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6GD3 \| pdb_00006gd3	Download File View File

Structure of HuR RRM3 in complex with RNA (UAUUUA)

Pabis, M., Sattler, M.

(2019) Nucleic Acids Res 47: 1011-1029

Released	2018-10-31
Method	X-RAY DIFFRACTION 1.35 Å
Organisms	Homo sapiens synthetic construct
Macromolecule	ELAV-like protein 1 (protein) RNA (5'-R(PUPAPUPUPUPA)-3') (nucleic acid)
Unique Ligands	NA

1 to 10 of 10 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

3HI9 | pdb_00003hi9

The x-ray crystal structure of the first RNA recognition motif (RRM1) of the AU-rich element (ARE) binding protein HuR at 2.0 angstrom resolution

4ED5 | pdb_00004ed5

Crystal structure of the two N-terminal RRM domains of HuR complexed with RNA

4EGL | pdb_00004egl

Crystal structure of two tandem RNA recognition motifs of Human antigen R

4FXV | pdb_00004fxv

Crystal structure of an ELAV-like protein 1 (ELAVL1) from Homo sapiens at 1.90 A resolution

5SZW | pdb_00005szw

NMR solution structure of the RRM1 domain of the post-transcriptional regulator HuR

6G2K | pdb_00006g2k

Structure of HuR RRM3 in complex with RNA (UUUUUU)

6GC5 | pdb_00006gc5

Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM

6GD1 | pdb_00006gd1

Structure of HuR RRM3

6GD2 | pdb_00006gd2

Structure of HuR RRM3 in complex with RNA

6GD3 | pdb_00006gd3

Structure of HuR RRM3 in complex with RNA (UAUUUA)

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Symmetry Type

SCOP Classification

3HI9 | pdb_00003hi9

4ED5 | pdb_00004ed5

4EGL | pdb_00004egl

4FXV | pdb_00004fxv

5SZW | pdb_00005szw

6G2K | pdb_00006g2k

6GC5 | pdb_00006gc5

6GD1 | pdb_00006gd1

6GD2 | pdb_00006gd2

6GD3 | pdb_00006gd3