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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Chemical ID(s) = COM

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Search Summary

This query matches 48 Structures.

Refinements

Structure Determination Methodology

experimental (48)

Scientific Name of Source Organism

	Methanothermobacter marburgensis str. Marburg (11)
	Homo sapiens (6)
	Xanthobacter autotrophicus Py2 (5)
	Methanothermobacter marburgensis (4)
	Methanothermococcus thermolithotrophicus DSM 2095 (4)
	Methanococcus maripaludis (3)
	Candidatus Ethanoperedens thermophilum (2)
	Methanothermobacter thermautotrophicus (2)
	Methanothermobacter wolfeii (2)
	Methanotorris formicicus Mc-S-70 (2)

More...

Taxonomy

	Archaea (36)
	Bacteria (6)
	Eukaryota (6)

Experimental Method

	X-RAY DIFFRACTION (43)
	ELECTRON MICROSCOPY (5)

Polymer Entity Type

Protein (48)

Refinement Resolution (Å)

	0.5 - 1.0 (1)
	1.0 - 1.5 (11)
	1.5 - 2.0 (13)
	2.0 - 2.5 (14)
	2.5 - 3.0 (8)
	3.0 - 3.5 (1)

Release Date

	1995 - 1999 (1)
	2000 - 2004 (5)
	2005 - 2009 (2)
	2010 - 2014 (13)
	2015 - 2019 (14)
	2020 - 2024 (10)
	2025 - 2029 (3)

Enzyme Classification Name

	Transferases (33)
	Oxidoreductases (10)
	Translocases (1)
	Hydrolases (1)

Symmetry Type

	Cyclic (39)
	Asymmetric (11)
	Dihedral (1)

SCOP Classification

	Alpha and beta proteins (a+b) (30)
	All alpha proteins (23)
	Alpha and beta proteins (a/b) (8)
	Artifacts (4)
	Multi-domain proteins (alpha and beta) (3)

AllSelected

1 to 25 of 48 Structures

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1E6V \| pdb_00001e6v	Download File View File

Methyl-coenzyme M reductase from Methanopyrus kandleri

Grabarse, W., Ermler, U.

(2000) J Mol Biology 303: 329

Released	2000-10-18
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Methanopyrus kandleri
Macromolecule	METHYL-COENZYME M REDUCTASE I ALPHA SUBUNIT (protein) METHYL-COENZYME M REDUCTASE I BETA SUBUNIT (protein) METHYL-COENZYME M REDUCTASE I GAMMA SUBUNIT (protein)
Unique Ligands	COM, F43, TP7

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1E6Y \| pdb_00001e6y	Download File View File

Methyl-coenzyme M reductase from Methanosarcina barkeri

Grabarse, W., Ermler, U.

(2000) J Mol Biology 303: 329

Released	2000-10-18
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Methanosarcina barkeri
Macromolecule	METHYL-COENZYME M REDUCTASE I BETA SUBUNIT (protein) METHYL-COENZYME M REDUCTASE SUBUNIT ALPHA (protein) METHYL-COENZYME M REDUCTASE SUBUNIT GAMMA (protein)
Unique Ligands	COM, F43, GOL, TP7

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1HBN \| pdb_00001hbn	Download File View File

METHYL-COENZYME M REDUCTASE

Ermler, U., Grabarse, W.

(2001) J Mol Biology 309: 315

Released	2001-08-16
Method	X-RAY DIFFRACTION 1.16 Å
Organisms	Methanothermobacter thermautotrophicus
Macromolecule	METHYL-COENZYME M REDUCTASE I ALPHA SUBUNIT (protein) METHYL-COENZYME M REDUCTASE I BETA SUBUNIT (protein) METHYL-COENZYME M REDUCTASE I GAMMA SUBUNIT (protein)
Unique Ligands	CL, COM, F43, GOL, MG, NA, TP7, ZN

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1HBO \| pdb_00001hbo	Download File View File

METHYL-COENZYME M REDUCTASE MCR-RED1-SILENT

Grabarse, W.

(2001) J Mol Biology 309: 315

Released	2001-08-16
Method	X-RAY DIFFRACTION 1.78 Å
Organisms	Methanothermobacter thermautotrophicus
Macromolecule	METHYL-COENZYME M REDUCTASE I ALPHA SUBUNIT (protein) METHYL-COENZYME M REDUCTASE I BETA SUBUNIT (protein) METHYL-COENZYME M REDUCTASE I GAMMA SUBUNIT (protein)
Unique Ligands	CL, COM, F43, GOL, MG, NA, TP7, ZN

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1HBU \| pdb_00001hbu	Download File View File

METHYL-COENZYME M REDUCTASE IN THE MCR-RED1-SILENT STATE IN COMPLEX with COENZYME M

Ermler, U., Grabarse, W.

(2001) J Mol Biology 309: 315

Released	2001-08-16
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Methanothermobacter marburgensis str. Marburg
Macromolecule	METHYL-COENZYME M REDUCTASE I ALPHA SUBUNIT (protein) METHYL-COENZYME M REDUCTASE I BETA SUBUNIT (protein) METHYL-COENZYME M REDUCTASE I GAMMA SUBUNIT (protein)
Unique Ligands	CL, COM, F43, GOL, MG, NA, TP7, ZN

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1MRO \| pdb_00001mro	Download File View File

METHYL-COENZYME M REDUCTASE

Ermler, U., Grabarse, W.

(1997) Science 278: 1457-1462

Released	1998-11-11
Method	X-RAY DIFFRACTION 1.16 Å
Organisms	Methanothermobacter marburgensis str. Marburg
Macromolecule	METHYL-COENZYME M REDUCTASE (protein)
Unique Ligands	COM, F43, GOL, NA, TP7, ZN

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2C3C \| pdb_00002c3c	Download File View File

2.01 Angstrom X-ray crystal structure of a mixed disulfide between coenzyme M and NADPH-dependent oxidoreductase 2-ketopropyl coenzyme M carboxylase

Pandey, A.S., Nocek, B., Clark, D.D., Ensign, S.A., Peters, J.W.

(2006) Biochemistry 45: 113

Released	2005-12-12
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Xanthobacter autotrophicus Py2
Macromolecule	2-OXOPROPYL-COM REDUCTASE (protein)
Unique Ligands	ACN, COM, FAD, NAP

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2C3D \| pdb_00002c3d	Download File View File

2.15 Angstrom crystal structure of 2-ketopropyl coenzyme M oxidoreductase carboxylase with a coenzyme M disulfide bound at the active site

Pandey, A.S., Nocek, B., Clark, D.D., Ensign, S.A., Peters, J.W.

(2006) Biochemistry 45: 113

Released	2005-11-07
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Xanthobacter autotrophicus Py2
Macromolecule	2-OXOPROPYL-COM REDUCTASE (protein)
Unique Ligands	COM, FAD

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3M1V \| pdb_00003m1v	Download File View File

Structural Insight into Methyl-Coenzyme M Reductase Chemistry using Coenzyme B Analogues

Cedervall, P.E., Dey, M., Ragsdale, S.W., Wilmot, C.M.

(2010) Biochemistry 49: 7683-7693

Released	2010-09-15
Method	X-RAY DIFFRACTION 1.45 Å
Organisms	Methanothermobacter marburgensis str. Marburg
Macromolecule	Methyl-coenzyme M reductase I subunit alpha (protein) Methyl-coenzyme M reductase I subunit beta (protein) Methyl-coenzyme M reductase I subunit gamma (protein)
Unique Ligands	ACT, COM, EDO, F43, MG, PEG, TP7, ZN

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3M2R \| pdb_00003m2r	Download File View File

Structural Insight into Methyl-Coenzyme M Reductase Chemistry using Coenzyme B Analogues

Cedervall, P.E., Dey, M., Ragsdale, S.W., Wilmot, C.M.

(2010) Biochemistry 49: 7683-7693

Released	2010-09-15
Method	X-RAY DIFFRACTION 1.3 Å
Organisms	Methanothermobacter marburgensis str. Marburg
Macromolecule	Methyl-coenzyme M reductase I subunit alpha (protein) Methyl-coenzyme M reductase I subunit beta (protein) Methyl-coenzyme M reductase I subunit gamma (protein)
Unique Ligands	COM, EDO, F43, MG, PEG, TP7, TPZ, ZN

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3M2U \| pdb_00003m2u	Download File View File

Structural Insight into Methyl-Coenzyme M Reductase Chemistry using Coenzyme B Analogues

Cedervall, P.E., Dey, M., Ragsdale, S.W., Wilmot, C.M.

(2010) Biochemistry 49: 7683-7693

Released	2010-09-15
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Methanothermobacter marburgensis str. Marburg
Macromolecule	Methyl-coenzyme M reductase I subunit alpha (protein) Methyl-coenzyme M reductase I subunit beta (protein) Methyl-coenzyme M reductase I subunit gamma (protein)
Unique Ligands	ACT, COM, EDO, F43, MG, PEG, TP7, TXZ, ZN

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3M2V \| pdb_00003m2v	Download File View File

Structural Insight into Methyl-Coenzyme M Reductase Chemistry using Coenzyme B Analogues

Cedervall, P.E., Dey, M., Ragsdale, S.W., Wilmot, C.M.

(2010) Biochemistry 49: 7683-7693

Released	2010-09-15
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Methanothermobacter marburgensis str. Marburg
Macromolecule	Methyl-coenzyme M reductase I subunit alpha (protein) Methyl-coenzyme M reductase I subunit beta (protein) Methyl-coenzyme M reductase I subunit gamma (protein)
Unique Ligands	ACT, COM, EDO, F43, MG, TP7, XP8, ZN

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3M30 \| pdb_00003m30	Download File View File

Structural Insight into Methyl-Coenzyme M Reductase Chemistry using Coenzyme B Analogues

Cedervall, P.E., Dey, M., Ragsdale, S.W., Wilmot, C.M.

(2010) Biochemistry 49: 7683-7693

Released	2010-09-15
Method	X-RAY DIFFRACTION 1.45 Å
Organisms	Methanothermobacter marburgensis str. Marburg
Macromolecule	Methyl-coenzyme M reductase I subunit alpha (protein) Methyl-coenzyme M reductase I subunit beta (protein) Methyl-coenzyme M reductase I subunit gamma (protein)
Unique Ligands	ACT, COM, EDO, F43, MG, PEG, TP7, XP9, ZN

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3M32 \| pdb_00003m32	Download File View File

Structural Insight into Methyl-Coenzyme M Reductase Chemistry using Coenzyme B Analogues

Cedervall, P.E., Dey, M., Ragsdale, S.W., Wilmot, C.M.

(2010) Biochemistry 49: 7683-7693

Released	2010-09-15
Method	X-RAY DIFFRACTION 1.35 Å
Organisms	Methanothermobacter marburgensis str. Marburg
Macromolecule	Methyl-coenzyme M reductase I subunit alpha (protein) Methyl-coenzyme M reductase I subunit beta (protein) Methyl-coenzyme M reductase I subunit gamma (protein)
Unique Ligands	ACT, COM, EDO, F43, MG, PEG, SHT, TP7, ZN

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3POT \| pdb_00003pot	Download File View File

Structural analysis of a Ni(III)-methyl species in methyl-coenzyme M reductase from Methanothermobacter marburgensis

Cedervall, P.E., Wilmot, C.M.

(2011) J Am Chem Soc 133: 5626-5628

Released	2011-04-13
Method	X-RAY DIFFRACTION 1.2 Å
Organisms	Methanothermobacter marburgensis
Macromolecule	Methyl-coenzyme M reductase I subunit alpha (protein) Methyl-coenzyme M reductase I subunit beta (protein) Methyl-coenzyme M reductase I subunit gamma (protein)
Unique Ligands	06C, COM, EDO, F43, K, MG, TP7, TXZ

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3Q6J \| pdb_00003q6j	Download File View File

Structural basis for carbon dioxide binding by 2-ketopropyl coenzyme M Oxidoreductase/Carboxylase

Pandey, A.S., Mulder, D.W., Ensign, S.A., Peters, J.W.

(2011) FEBS Lett 585: 459-464

Released	2011-02-16
Method	X-RAY DIFFRACTION 1.92 Å
Organisms	Xanthobacter autotrophicus Py2
Macromolecule	2-oxopropyl-CoM reductase, carboxylating (protein)
Unique Ligands	ACN, BCT, CO2, COM, FAD, KPC, MG, NAP

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3SQG \| pdb_00003sqg	Download File View File

Crystal structure of a methyl-coenzyme M reductase purified from Black Sea mats

Shima, S., Krueger, M., Weinert, T., Demmer, U., Thauer, R.K., Ermler, U.

(2011) Nature 481: 98-101

Released	2011-11-30
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	uncultured archaeon
Macromolecule	Methyl coenzyme M reductase, alpha subunit (protein) Methyl-coenzyme M reductase, beta subunit (protein) Methyl-coenzyme M reductase, gamma subunit (protein)
Unique Ligands	1PE, CA, CL, COM, GOL, M43, P6G, PGE, SO4, TP7

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4AY8 \| pdb_00004ay8	Download File View File

SeMet-derivative of a methyltransferase from M. mazei

Hoeppner, A., Thomas, F., Rueppel, A., Hensel, R., Blankenfeldt, W., Bayer, P., Faust, A.

(2012) Acta Crystallogr D Biol Crystallogr 68: 1549

Released	2012-10-31
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Methanosarcina mazei
Macromolecule	METHYLCOBALAMIN\: COENZYME M METHYLTRANSFERASE (protein)
Unique Ligands	COM, GOL, MRD, ZN

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4POK \| pdb_00004pok	Download File View File

Crystal structures of thioredoxin with mesna at 2.5A resolution

Sridhar, V., Chie-Leon, B., Badger, J., Nienaber, V.L., Hausheer, F.H.

(2014) J Pharmacol Clin Toxicol 2: 1026

Released	2014-10-29
Method	X-RAY DIFFRACTION 2.52 Å
Organisms	Homo sapiens
Macromolecule	Thioredoxin (protein)
Unique Ligands	COM

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4POL \| pdb_00004pol	Download File View File

Crystal structures of thioredoxin with mesna at 2.8A resolution

Sridhar, V., Chie-Leon, B., Badger, J., Nienaber, V.L., Hausheer, F.H.

(2014) J Pharmacol Clin Toxicol 2: 1026

Released	2014-10-29
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	Thioredoxin (protein)
Unique Ligands	COM

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4POM \| pdb_00004pom	Download File View File

Crystal structures of thioredoxin with mesna at 1.85A resolution

Sridhar, V., Chie-Leon, B., Badger, J., Nienaber, V.L., Hausheer, F.H.

(2014) J Pharmacol Clin Toxicol 2: 1026

Released	2014-10-29
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens
Macromolecule	Thioredoxin (protein)
Unique Ligands	COM

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4RQR \| pdb_00004rqr	Download File View File

Crystal Structure of Human Glutaredoxin with MESNA

Badger, J., Sridhar, V., Logan, C., Hausheer, F.H., Nienaber, V.L.

(2015) Molecules 20: 4928-4950

Released	2015-04-01
Method	X-RAY DIFFRACTION 1.08 Å
Organisms	Homo sapiens
Macromolecule	Glutaredoxin-1 (protein)
Unique Ligands	COM

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4RQX \| pdb_00004rqx	Download File View File

Crystal structure of human peroxiredoxin 4(THIOREDOXIN PEROXIDASE) with MESNA

Badger, J., Sridhar, V., Logan, C., Hausheer, F.H., Nienaber, V.L.

(2015) Molecules 20: 4928-4950

Released	2015-04-01
Method	X-RAY DIFFRACTION 2.256 Å
Organisms	Homo sapiens
Macromolecule	Peroxiredoxin-4 (protein)
Unique Ligands	COM

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4TT7 \| pdb_00004tt7	Download File View File

Crystal structure of human ALK with a covalent modification

Badger, J., Sridhar, V., Chie-Leon, B., Nienaber, V.L., Hausheer, F.H.

(2015) Onco Targets Ther 8: 375-383

Released	2015-02-11
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	ALK tyrosine kinase receptor (protein)
Unique Ligands	COM, EDO

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5A0Y \| pdb_00005a0y	Download File View File

METHYL-COENZYME M REDUCTASE FROM METHANOTHERMOBACTER MARBURGENSIS AT 1.1 A RESOLUTION

Wagner, T., Ermler, U.

(2016) Angew Chem Int Ed Engl 55: 10630

Released	2016-05-11
Method	X-RAY DIFFRACTION 1.1 Å
Organisms	Methanothermobacter marburgensis
Macromolecule	METHYL-COENZYME M REDUCTASE I SUBUNIT ALPHA (protein) METHYL-COENZYME M REDUCTASE I SUBUNIT BETA (protein) METHYL-COENZYME M REDUCTASE I SUBUNIT GAMMA (protein)
Unique Ligands	CL, COM, F43, K, MG, NA, TP7

1 to 25 of 48 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1E6V | pdb_00001e6v

1E6Y | pdb_00001e6y

1HBN | pdb_00001hbn

1HBO | pdb_00001hbo

1HBU | pdb_00001hbu

1MRO | pdb_00001mro

2C3C | pdb_00002c3c

2C3D | pdb_00002c3d

3M1V | pdb_00003m1v

3M2R | pdb_00003m2r

3M2U | pdb_00003m2u

3M2V | pdb_00003m2v

3M30 | pdb_00003m30

3M32 | pdb_00003m32

3POT | pdb_00003pot

3Q6J | pdb_00003q6j

3SQG | pdb_00003sqg

4AY8 | pdb_00004ay8

4POK | pdb_00004pok

4POL | pdb_00004pol

4POM | pdb_00004pom

4RQR | pdb_00004rqr

4RQX | pdb_00004rqx

4TT7 | pdb_00004tt7

5A0Y | pdb_00005a0y