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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Zhang, T."

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Search Summary

This query matches 462 Structures.

Refinements

Structure Determination Methodology

experimental (462)

Scientific Name of Source Organism

	Homo sapiens (222)
	Mus musculus (42)
	synthetic construct (22)
	Severe acute respiratory syndrome coronavirus 2 (18)
	Escherichia coli (16)
	Penaeus japonicus (16)
	Drosophila melanogaster (13)
	Rhodopseudomonas palustris HaA2 (8)
	Saccharomyces cerevisiae (8)
	Saccharomyces cerevisiae S288C (8)

More...

Taxonomy

	Eukaryota (344)
	Bacteria (105)
	Riboviria (33)
	other sequences (24)
	Eukaryota (eukaryotes) (5)
	Duplodnaviria (4)
	environmental samples (2)
	Varidnaviria (1)
	Viruses incertae sedis (1)
	unclassified bacterial viruses (1)

Experimental Method

	X-RAY DIFFRACTION (344)
	ELECTRON MICROSCOPY (114)
	SOLUTION NMR (4)
	SOLUTION SCATTERING (1)

Polymer Entity Type

	Protein (462)
	DNA (12)
	RNA (9)

Refinement Resolution (Å)

	1.0 - 1.5 (21)
	1.5 - 2.0 (73)
	2.0 - 2.5 (143)
	2.5 - 3.0 (108)
	3.0 - 3.5 (59)
	3.5 - 4.0 (39)
	4.0 - 4.5 (8)
	> 4.5 (7)

Release Date

	1995 - 1999 (8)
	2000 - 2004 (10)
	2005 - 2009 (3)
	2010 - 2014 (35)
	2015 - 2019 (107)
	2020 - 2024 (270)
	2025 - 2029 (29)

Enzyme Classification Name

	Hydrolases (107)
	Transferases (92)
	Oxidoreductases (85)
	Translocases (8)
	Ligases (6)
	Lyases (5)
	Isomerases (4)

Membrane Protein Annotation

	PDBTM (47)
	MemProtMD (31)
	OPM (20)
	mpstruc (19)

Symmetry Type

	Asymmetric (270)
	Cyclic (125)
	Octahedral (37)
	Dihedral (32)
	Icosahedral (1)

SCOP Classification

	Alpha and beta proteins (a/b) (28)
	Alpha and beta proteins (a+b) (43)
	All alpha proteins (33)
	Artifacts (34)
	All beta proteins (29)
	Coiled coil proteins (17)
	Small proteins (6)
	Designed proteins (1)
	Multi-domain proteins (alpha and beta) (1)

AllSelected

1 to 25 of 462 Structures

Page 1 of 19

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1C94 \| pdb_00001c94	Download File View File

REVERSING THE SEQUENCE OF THE GCN4 LEUCINE ZIPPER DOES NOT AFFECT ITS FOLD.

Mittl, P.R.E., Deillon, C.A., Sargent, D., Liu, N., Klauser, S., Thomas, R.M., Gutte, B., Gruetter, M.G.

(2000) Proc Natl Acad Sci U S A 97: 2562-2566

Released	2000-03-22
Method	X-RAY DIFFRACTION 2.08 Å
Macromolecule	RETRO-GCN4 LEUCINE ZIPPER (protein)

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1GCL \| pdb_00001gcl	Download File View File

GCN4 LEUCINE ZIPPER CORE MUTANT P-LI

Harbury, P.B., Zhang, T., Kim, P.S., Alber, T.

(1993) Science 262: 1401-1407

Released	1995-06-03
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	GCN4 (protein)

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1GCM \| pdb_00001gcm	Download File View File

GCN4 LEUCINE ZIPPER CORE MUTANT P-LI

Harbury, P.B., Kim, P.S., Alber, T.

(1994) Nature 371: 80-83

Released	1996-01-29
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	GCN4P-II (protein)

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1IJ1 \| pdb_00001ij1	Download File View File

GCN4-pVLT Coiled-coil Trimer with Threonine at the d(12) Position

Akey, D.L., Malashkevich, V.N., Kim, P.S.

(2001) Biochemistry 40: 6352-6360

Released	2001-08-08
Method	X-RAY DIFFRACTION 1.86 Å
Organisms	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Macromolecule	GENERAL CONTROL PROTEIN GCN4 (protein)
Unique Ligands	ZN

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1OP0 \| pdb_00001op0	Download File View File

Crystal Structure of AaV-SP-I, a Glycosylated Snake Venom Serine Proteinase from Agkistrodon acutus

Zhu, Z., Teng, M., Niu, L.

(2005) J Biological Chem 280: 10524-10529

Released	2004-05-25
Method	X-RAY DIFFRACTION 2 Å
Organisms	Deinagkistrodon acutus
Macromolecule	Venom serine proteinase (protein)
Unique Ligands	SO4
Unique branched monosaccharides	FUC, NAG

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1OP2 \| pdb_00001op2	Download File View File

Crystal Structure of AaV-SP-II, a Glycosylated Snake Venom Serine Proteinase from Agkistrodon acutus

Zhu, Z., Teng, M., Niu, L.

(2005) J Biological Chem 280: 10524-10529

Released	2004-05-25
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Deinagkistrodon acutus
Macromolecule	Venom serine proteinase (protein)
Unique Ligands	NAG, SO4

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1PYN \| pdb_00001pyn	Download File View File

DUAL-SITE POTENT, SELECTIVE PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR USING A LINKED FRAGMENT STRATEGY AND A MALONATE HEAD ON THE FIRST SITE

Szczepankiewicz, B.G., Liu, G., Hajduk, P.J., Abad-Zapatero, C., Zhonghua, P., Lubben, T., Trevillyan, J.M., Stashko, M., Ballaron, S.J., Liang, H.

(2003) Bioorg Med Chem Lett 13: 3129-3132

Released	2003-09-16
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	Protein-tyrosine phosphatase, non-receptor type 1 (protein)
Unique Ligands	941

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1Q1M \| pdb_00001q1m	Download File View File

A Highly Efficient Approach to a Selective and Cell Active PTP1B inhibitors

Liu, G., Xin, Z., Pei, Z., Hajduk, P.J., Abad-Zapatero, C., Hutchins, C.W., Zhao, H., Lubben, T.H., Ballaron, S.J., Haasch, D.L., Kaszubska, W., Rondinone, C.M., Trevillyan, J.M., Jirousek, M.R.

(2003) J Med Chem 46: 4232-4235

Released	2003-09-16
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Protein-tyrosine phosphatase, non-receptor type 1 (protein)
Unique Ligands	234

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1QXK \| pdb_00001qxk	Download File View File

Monoacid-Based, Cell Permeable, Selective Inhibitors of Protein Tyrosine Phosphatase 1B

Xin, Z., Liu, G., Abad-Zapatero, C., Pei, Z., Szczepankiewick, B.G., Li, X., Zhang, T., Hutchins, C.W., Hajduk, P.J., Ballaron, S.J., Stashko, M.A., Lubben, T.H., Trevillyan, J.M., Jirousek, M.R.

(2003) Bioorg Med Chem Lett 13: 3947-3950

Released	2003-10-28
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Protein-tyrosine phosphatase, non-receptor type 1 (protein)
Unique Ligands	429

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1RB4 \| pdb_00001rb4	Download File View File

ANTIPARALLEL TRIMER OF GCN4-LEUCINE ZIPPER CORE MUTANT AS N16A TETRAGONAL AUTOMATIC SOLUTION

Holton, J., Alber, T.

(2004) Proc Natl Acad Sci U S A 101: 1537-1542

Released	2004-01-13
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Macromolecule	General control protein GCN4 (protein)

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1RB5 \| pdb_00001rb5	Download File View File

ANTIPARALLEL TRIMER OF GCN4-LEUCINE ZIPPER CORE MUTANT AS N16A TRIGONAL FORM

Holton, J., Alber, T.

(2004) Proc Natl Acad Sci U S A 101: 1537-1542

Released	2004-01-13
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Macromolecule	General control protein GCN4 (protein)

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1RB6 \| pdb_00001rb6	Download File View File

ANTIPARALLEL TRIMER OF GCN4-LEUCINE ZIPPER CORE MUTANT AS N16A TETRAGONAL FORM

Holton, J., Alber, T.

(2004) Proc Natl Acad Sci U S A 101: 1537-1542

Released	2004-01-13
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Macromolecule	General control protein GCN4 (protein)
Unique Ligands	CL, K

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1SWI \| pdb_00001swi	Download File View File

GCN4-LEUCINE ZIPPER CORE MUTANT AS N16A COMPLEXED WITH BENZENE

Gonzalez, L., Plecs, J., Alber, T.

(1996) Nat Struct Biol 3: 510-515

Released	1996-11-08
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	GCN4P1 (protein)
Unique Ligands	BNZ

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1ZII \| pdb_00001zii	Download File View File

GCN4-LEUCINE ZIPPER CORE MUTANT ASN16ABA IN THE DIMERIC STATE

Gonzalez Junior, L., Brown, R.A., Richardson, D., Alber, T.

(1996) Nat Struct Biol 3: 1002-1010

Released	1997-07-07
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	GENERAL CONTROL PROTEIN GCN4 (protein)

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1ZIJ \| pdb_00001zij	Download File View File

GCN4-LEUCINE ZIPPER CORE MUTANT ASN16ABA IN THE TRIMERIC STATE

Gonzalez Junior, L., Brown, R.A., Richardson, D., Alber, T.

(1996) Nat Struct Biol 3: 1002-1010

Released	1997-07-07
Method	X-RAY DIFFRACTION 2 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	GENERAL CONTROL PROTEIN GCN4 (protein)

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1ZIK \| pdb_00001zik	Download File View File

GCN4-LEUCINE ZIPPER CORE MUTANT ASN16LYS IN THE DIMERIC STATE

Gonzalez Junior, L., Woolfson, D.N., Alber, T.

(1996) Nat Struct Biol 3: 1011-1018

Released	1997-07-07
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	GENERAL CONTROL PROTEIN GCN4 (protein)

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1ZIL \| pdb_00001zil	Download File View File

GCN4-LEUCINE ZIPPER CORE MUTANT ASN16GLN IN THE DIMERIC STATE

Gonzalez Junior, L., Woolfson, D.N., Alber, T.

(1996) Nat Struct Biol 3: 1011-1018

Released	1997-07-07
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	GENERAL CONTROL PROTEIN GCN4 (protein)

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1ZIM \| pdb_00001zim	Download File View File

GCN4-LEUCINE ZIPPER CORE MUTANT ASN16GLN IN THE TRIMERIC STATE

Gonzalez Junior, L., Woolfson, D.N., Alber, T.

(1996) Nat Struct Biol 3: 1011-1018

Released	1997-07-07
Method	X-RAY DIFFRACTION 2 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	GENERAL CONTROL PROTEIN GCN4 (protein)

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2MLB \| pdb_00002mlb	Download File View File

NMR solution structure of a computational designed protein based on template of human erythrocytic ubiquitin

Xiong, P., Wang, M., Zhang, J., Chen, Q., Liu, H.

(2014) Nat Commun 5: 5330-5330

Released	2014-10-29
Method	SOLUTION NMR
Organisms	synthetic construct
Macromolecule	redesigned ubiquitin (protein)

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2MN4 \| pdb_00002mn4	Download File View File

NMR solution structure of a computational designed protein based on structure template 1cy5

Xiong, P., Wang, M., Zhang, J., Chen, Q., Liu, H.

(2014) Nat Commun 5: 5330-5330

Released	2014-10-29
Method	SOLUTION NMR
Organisms	synthetic construct
Macromolecule	Computational designed protein based on structure template 1cy5 (protein)

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3DOE \| pdb_00003doe	Download File View File

Complex of ARL2 and BART, Crystal Form 1

Zhang, T., Li, S., Ding, J.

(2009) Structure 17: 602-610

Released	2009-03-03
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Homo sapiens
Macromolecule	ADP-ribosylation factor-like protein 2 (protein) ADP-ribosylation factor-like protein 2-binding protein (protein)
Unique Ligands	GTP, MG

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3DOF \| pdb_00003dof	Download File View File

Complex of ARL2 and BART, Crystal Form 2

Zhang, T., Li, S., Ding, J.

(2009) Structure 17: 602-610

Released	2009-03-03
Method	X-RAY DIFFRACTION 3.3 Å
Organisms	Homo sapiens
Macromolecule	ADP-ribosylation factor-like protein 2 (protein) ADP-ribosylation factor-like protein 2-binding protein (protein)
Unique Ligands	GTP, MG

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3K7Z \| pdb_00003k7z	Download File View File

GCN4-Leucine zipper core mutant as N16A trigonal automatic solution

Holton, J., Alber, T., TB Structural Genomics Consortium (TBSGC)

(2004) Proc Natl Acad Sci U S A 101: 1537

Released	2009-11-24
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Macromolecule	General control protein GCN4 (protein)

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3OV6 \| pdb_00003ov6	Download File View File

CD1c in complex with MPM (mannosyl-beta1-phosphomycoketide)

Scharf, L., Li, N.S., Hawk, A.J., Garzon, D., Zhang, T., Kazen, A.R., Shah, S., Haddadian, E.J., Saghatelian, A., Faraldo-Gomez, J.D., Meredith, S.C., Piccirilli, J.A., Adams, E.J.

(2010) Immunity 33: 853-862

Released	2011-01-19
Method	X-RAY DIFFRACTION 2.502 Å
Organisms	Homo sapiens
Macromolecule	Beta-2-microglobulin, T-cell surface glycoprotein CD1c, T-cell surface glycoprotein CD1b (protein)
Unique Ligands	D12, MK0, NAG

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3RIB \| pdb_00003rib	Download File View File

Human lysine methyltransferase Smyd2 in complex with AdoHcy

Xu, S., Zhang, T., Zhong, C., Ding, J.

(2011) J Mol Cell Biol 3: 293-300

Released	2011-07-20
Method	X-RAY DIFFRACTION 2.79 Å
Organisms	Homo sapiens
Macromolecule	N-lysine methyltransferase SMYD2 (protein)
Unique Ligands	SAH, SO4, ZN

1 to 25 of 462 Structures

Page 1 of 19

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1C94 | pdb_00001c94

1GCL | pdb_00001gcl

1GCM | pdb_00001gcm

1IJ1 | pdb_00001ij1

1OP0 | pdb_00001op0

1OP2 | pdb_00001op2

1PYN | pdb_00001pyn

1Q1M | pdb_00001q1m

1QXK | pdb_00001qxk

1RB4 | pdb_00001rb4

1RB5 | pdb_00001rb5

1RB6 | pdb_00001rb6

1SWI | pdb_00001swi

1ZII | pdb_00001zii

1ZIJ | pdb_00001zij

1ZIK | pdb_00001zik

1ZIL | pdb_00001zil

1ZIM | pdb_00001zim

2MLB | pdb_00002mlb

2MN4 | pdb_00002mn4

3DOE | pdb_00003doe

3DOF | pdb_00003dof

3K7Z | pdb_00003k7z

3OV6 | pdb_00003ov6

3RIB | pdb_00003rib