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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Patel, M."

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Search Summary

This query matches 64 Structures.

Refinements

Structure Determination Methodology

experimental (64)

Scientific Name of Source Organism

	Homo sapiens (24)
	Human immunodeficiency virus 1 (7)
	Rana boylii (7)
	Streptococcus mutans (5)
	Pseudomonas aeruginosa PAO1 (3)
	Escherichia coli (2)
	Haemophilus influenzae Rd KW20 (2)
	Rattus norvegicus (2)
	Staphylococcus aureus (2)
	Streptococcus intermedius (2)

More...

Taxonomy

	Eukaryota (33)
	Bacteria (18)
	Riboviria (7)

Experimental Method

	X-RAY DIFFRACTION (55)
	SOLUTION NMR (8)
	ELECTRON MICROSCOPY (1)

Polymer Entity Type

	Protein (57)
	DNA (10)

Refinement Resolution (Å)

	1.0 - 1.5 (4)
	1.5 - 2.0 (16)
	2.0 - 2.5 (23)
	2.5 - 3.0 (10)
	3.0 - 3.5 (2)
	4.0 - 4.5 (1)

Release Date

	2000 - 2004 (4)
	2005 - 2009 (9)
	2010 - 2014 (4)
	2015 - 2019 (15)
	2020 - 2024 (31)
	2025 - 2029 (1)

Enzyme Classification Name

	Transferases (18)
	Hydrolases (13)
	Lyases (4)

Symmetry Type

	Asymmetric (43)
	Cyclic (13)
	Dihedral (3)

SCOP Classification

	Alpha and beta proteins (a/b) (14)
	Alpha and beta proteins (a+b) (6)
	Artifacts (7)
	All alpha proteins (1)
	All beta proteins (2)
	Multi-domain proteins (alpha and beta) (3)

AllSelected

1 to 25 of 64 Structures

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1D9E \| pdb_00001d9e	Download File View File

STRUCTURE OF E. COLI KDO8P SYNTHASE

Radaev, S., Dastidar, P., Patel, M., Woodard, R.W., Gatti, D.L.

(2000) J Biological Chem 275: 9476-9484

Released	2000-05-10
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Escherichia coli
Macromolecule	3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (protein)
Unique Ligands	SO4

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1GG0 \| pdb_00001gg0	Download File View File

CRYSTAL STRUCTURE ANALYSIS OF KDOP SYNTHASE AT 3.0 A

Wagner, T., Kretsinger, R.H., Bauerle, R., Tolbert, W.D.

(2000) J Mol Biology 301: 233-238

Released	2000-10-04
Method	X-RAY DIFFRACTION 3 Å
Organisms	Escherichia coli
Macromolecule	3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (protein)
Unique Ligands	PO4

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1TVZ \| pdb_00001tvz	Download File View File

Crystal structure of 3-hydroxy-3-methylglutaryl-coenzyme A synthase from Staphylococcus aureus

Campobasso, N., Patel, M., Wilding, I.E., Kallender, H., Rosenberg, M., Gwynn, M.

(2004) J Biological Chem 279: 44883-44888

Released	2004-08-31
Method	X-RAY DIFFRACTION 2 Å
Organisms	Staphylococcus aureus
Macromolecule	3-hydroxy-3-methylglutaryl-CoA synthase (protein)
Unique Ligands	SO4

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1TXT \| pdb_00001txt	Download File View File

Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase

Campobasso, N., Patel, M., Wilding, I.E., Kallender, H., Rosenberg, M., Gwynn, M.

(2004) J Biological Chem 279: 44883-44888

Released	2004-08-31
Method	X-RAY DIFFRACTION 2.501 Å
Organisms	Staphylococcus aureus
Macromolecule	3-hydroxy-3-methylglutaryl-CoA synthase (protein)
Unique Ligands	CAA

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2N9C \| pdb_00002n9c	Download File View File

NRAS Isoform 5

Markowitz, J., Mal, T.K., Yuan, C., Courtney, N.B., Patel, M., Stiff, A.R., Blachly, J., Walker, C., Eisfeld, A., de la Chapelle, A., Carson III, W.E.

(2016) Protein Sci 25: 1069-1074

Released	2016-03-23
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	GTPase NRas (protein)

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2NNQ \| pdb_00002nnq	Download File View File

Crystal structure of human adipocyte fatty acid binding protein in complex with ((2'-(5-ethyl-3,4-diphenyl-1H-pyrazol-1-yl)-3-biphenylyl)oxy)acetic acid

Jacobson, B.L.

(2007) Bioorg Med Chem Lett 17: 3511-3515

Released	2007-06-12
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Fatty acid-binding protein, adipocyte (protein)
Unique Ligands	SO4, T4B

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2VSZ \| pdb_00002vsz	Download File View File

Crystal Structure of the ELMO1 PH domain

Komander, D., Patel, M., Barford, D., Cote, J.-F.

(2008) Mol Biol Cell 19: 4837

Released	2009-03-10
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	ENGULFMENT AND CELL MOTILITY PROTEIN 1 (protein)

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3AB3 \| pdb_00003ab3	Download File View File

Crystal structure of p115RhoGEF RGS domain in complex with G alpha 13

Kukimoto-Niino, M., Mishima, C., Shirouzu, M., Kozasa, T., Yokoyama, S.

(2011) J Biological Chem 286: 20625-20636

Released	2010-12-29
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Guanine nucleotide-binding protein G(k) subunit alpha, Guanine nucleotide-binding protein subunit alpha-13 (protein) Rho guanine nucleotide exchange factor 1 (protein)
Unique Ligands	ALF, GDP, MG

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3EM2 \| pdb_00003em2	Download File View File

A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6038

Campbell, N.H., Parkinson, G., Neidle, S.

(2009) Biochemistry 48: 1675-1680

Released	2008-10-14
Method	X-RAY DIFFRACTION 2.3 Å
Macromolecule	5'-D(DGPDGPDGPDGPDTPDTPDTPDTPDGPDGPDGPDG)-3' (nucleic acid)
Unique Ligands	K, NCE

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3EQW \| pdb_00003eqw	Download File View File

A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6042 in small unit cell

Campbell, N.H., Parkinson, G., Neidle, S.

(2009) Biochemistry 48: 1675-1680

Released	2008-10-14
Method	X-RAY DIFFRACTION 2.2 Å
Macromolecule	5'-D(DGPDGPDGPDGPDTPDTPDTPDTPDGPDGPDGPDG)-3' (nucleic acid)
Unique Ligands	K, NCI

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3ERU \| pdb_00003eru	Download File View File

A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6045

Campbell, N.H., Parkinson, G., Neidle, S.

(2009) Biochemistry 48: 1675-1680

Released	2008-10-14
Method	X-RAY DIFFRACTION 2 Å
Macromolecule	5'-D(DGPDGPDGPDGPDTPDTPDTPDTPDGPDGPDGPDG)-3' (nucleic acid)
Unique Ligands	K, NCJ

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3ES0 \| pdb_00003es0	Download File View File

A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6048

Campbell, N.H., Parkinson, G., Neidle, S.

(2009) Biochemistry 48: 1675-1680

Released	2008-10-14
Method	X-RAY DIFFRACTION 2.2 Å
Macromolecule	5'-D(DGPDGPDGPDGPDTPDTPDTPDTPDGPDGPDGPDG)-3' (nucleic acid)
Unique Ligands	K, NCK

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3ET8 \| pdb_00003et8	Download File View File

A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6054

Campbell, N.H., Parkinson, G., Neidle, S.

(2009) Biochemistry 48: 1675-1680

Released	2008-10-14
Method	X-RAY DIFFRACTION 2.45 Å
Macromolecule	5'-D(DGPDGPDGPDGPDTPDTPDTPDTPDGPDGPDGPDG)-3' (nucleic acid)
Unique Ligands	K, NCL

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3EUI \| pdb_00003eui	Download File View File

A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6042 in a large unit cell

Campbell, N.H., Parkinson, G., Neidle, S.

(2009) Biochemistry 48: 1675-1680

Released	2008-12-02
Method	X-RAY DIFFRACTION 2.2 Å
Macromolecule	5'-D(DGPDGPDGPDGPDTPDTPDTPDTPDGPDGPDGPDG)-3' (nucleic acid)
Unique Ligands	K, NC5, NCI, SPM

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3EUM \| pdb_00003eum	Download File View File

A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6066

Campbell, N.H., Parkinson, G., Neidle, S.

(2009) Biochemistry 48: 1675-1680

Released	2008-10-21
Method	X-RAY DIFFRACTION 1.78 Å
Macromolecule	5'-D(DGPDGPDGPDGPDTPDTPDTPDTPDGPDGPDGPDG)-3' (nucleic acid)
Unique Ligands	K, NCQ

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3L4C \| pdb_00003l4c	Download File View File

Structural basis of membrane-targeting by Dock180

Premkumar, L., Bobkov, A.A., Patel, M., Jaroszewski, L., Bankston, L.A., Stec, B., Vuori, K., Cote, J.-F., Liddington, R.C.

(2010) J Biological Chem 285: 13211-13222

Released	2010-02-23
Method	X-RAY DIFFRACTION 2.37 Å
Organisms	Homo sapiens
Macromolecule	Dedicator of cytokinesis protein 1 (protein)
Unique Ligands	BME

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3ZD1 \| pdb_00003zd1	Download File View File

STRUCTURE OF THE TWO C-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 2

Caesar, J.J.E., Goicoechea de Jorge, E., Pickering, M.C., Lea, S.M.

(2013) Proc Natl Acad Sci U S A 110: 4685

Released	2013-03-13
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	COMPLEMENT FACTOR H-RELATED PROTEIN 2 (protein)
Unique Ligands	EDO

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3ZD2 \| pdb_00003zd2	Download File View File

THE STRUCTURE OF THE TWO N-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 1 SHOWS FORMATION OF A NOVEL DIMERISATION INTERFACE

Caesar, J.J.E., Goicoechea de Jorge, E., Pickering, M.C., Lea, S.M.

(2013) Proc Natl Acad Sci U S A 110: 4685

Released	2013-03-13
Method	X-RAY DIFFRACTION 1.99 Å
Organisms	Homo sapiens
Macromolecule	COMPLEMENT FACTOR H-RELATED PROTEIN 1 (protein)
Unique Ligands	EDO

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6CPW \| pdb_00006cpw	Download File View File

Discovery of 3(S)-thiomethyl pyrrolidine ERK inhibitors for oncology

Hruza, A., Hruza, A.

(2018) Bioorg Med Chem Lett 28: 2029-2034

Released	2018-05-23
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Rattus norvegicus
Macromolecule	Mitogen-activated protein kinase 1 (protein)
Unique Ligands	F8V, SO4

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6DBP \| pdb_00006dbp	Download File View File

RNA-recognition motif 1 of human MSI2

Goldgur, Y., Kharas, M.G., Minuesa, G.

(2019) Nat Commun 10: 2691-2691

Released	2019-05-08
Method	X-RAY DIFFRACTION 1.603 Å
Organisms	Homo sapiens
Macromolecule	RNA-binding protein Musashi homolog 2 (protein)

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6DCG \| pdb_00006dcg	Download File View File

Discovery of MK-8353: An Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology

Boga, S.B., Deng, Y., Zhu, L., Nan, Y., Cooper, A., Shipps Jr., G.W., Doll, R., Shih, N., Zhu, H., Sun, R., Wang, T., Paliwal, S., Tsui, H., Gao, X., Yao, X., Desai, J., Wang, J., Alhassan, A.B., Kelly, J., Patel, M., Muppalla, K., Gudipati, S., Zhang, L., Buevich, A., Hesk, D., Carr, D., Dayananth, P., Mei, H., Cox, K., Sherborne, B., Hruza, A.W., Xiao, L., Jin, W., Long, B., Liu, G., Taylor, S.A., Kirschmeier, P., Windsor, W.T., Bishop, R., Samatar, A.A.

(2018) ACS Med Chem Lett 9: 761-767

Released	2018-08-08
Method	X-RAY DIFFRACTION 1.45 Å
Organisms	Rattus norvegicus
Macromolecule	Mitogen-activated protein kinase 1 (protein)
Unique Ligands	G67, SO4

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6DE7 \| pdb_00006de7	Download File View File

Crystal Structure at 4.3 A Resolution of Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env Trimer with Interdomain Stabilization 113C-429GCG in Complex with Broadly Neutralizing Antibodies PGT122 and 35O22

Gorman, J., Kwong, P.D.

(2018) Cell Host Microbe 23: 832-844.e6

Released	2018-06-06
Method	X-RAY DIFFRACTION 4.123 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	Unique protein chains: 6
Unique Ligands	NAG, SO4
Unique branched monosaccharides	BMA, MAN, NAG

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6E36 \| pdb_00006e36	Download File View File

The structure of the variable domain of Streptococcus intermedius antigen I/II (Pas)

Schormann, N., Deivanayagam, C.

(2021) J Bacteriol 203: e0017521-e0017521

Released	2019-07-17
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Streptococcus intermedius
Macromolecule	Probable cell-surface antigen I/II (protein)
Unique Ligands	MG

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6E3F \| pdb_00006e3f	Download File View File

The structure of the C-terminal domains (C123) of Streptococcus intermedius antigen I/II (Pas)

Schormann, N., Deivanayagam, C.

(2021) J Bacteriol 203: e0017521-e0017521

Released	2019-07-17
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Streptococcus intermedius
Macromolecule	Probable cell-surface antigen I/II (protein)
Unique Ligands	CA