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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Milligan, R.A."

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Search Summary

This query matches 13 Structures.

Refinements

Structure Determination Methodology

experimental (13)

Scientific Name of Source Organism

	Homo sapiens (11)
	Sus scrofa (3)
	Caenorhabditis elegans (1)
	Mus musculus (1)
	Thermus thermophilus HB27 (1)

Taxonomy

	Eukaryota (13)
	Bacteria (1)

Experimental Method

	ELECTRON MICROSCOPY (6)
	X-RAY DIFFRACTION (6)
	SOLUTION NMR (1)

Polymer Entity Type

Protein (13)

Refinement Resolution (Å)

	1.5 - 2.0 (1)
	2.0 - 2.5 (3)
	2.5 - 3.0 (3)
	3.0 - 3.5 (1)
	3.5 - 4.0 (1)
	4.0 - 4.5 (2)
	> 4.5 (1)

Release Date

	2005 - 2009 (1)
	2010 - 2014 (5)
	2015 - 2019 (4)
	2020 - 2024 (3)

Enzyme Classification Name

	Hydrolases (5)
	Ligases (3)
	Oxidoreductases (2)

Symmetry Type

	Asymmetric (9)
	Cyclic (2)
	Dihedral (2)

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1 to 13 of 13 Structures

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2LYC \| pdb_00002lyc	Download File View File

Structure of C-terminal domain of Ska1

Boeszoermenyi, A., Schmidt, J.C., Markus, M., Oberer, M., Cheeseman, I.M., Wagner, G., Arthanari, H.

(2012) Dev Cell 23: 968-980

Released	2012-10-24
Method	SOLUTION NMR
Organisms	Caenorhabditis elegans
Macromolecule	Spindle and kinetochore-associated protein 1 homolog (protein)

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3ERR \| pdb_00003err	Download File View File

Microtubule binding domain from mouse cytoplasmic dynein as a fusion with seryl-tRNA synthetase

Carter, A.P.

(2008) Science 322: 1691-1695

Released	2008-11-25
Method	X-RAY DIFFRACTION 2.27 Å
Organisms	Mus musculus Thermus thermophilus HB27
Macromolecule	fusion protein of microtubule binding domain from mouse cytoplasmic dynein and seryl-tRNA synthetase from Thermus thermophilus (protein)
Unique Ligands	AMP

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3NRX \| pdb_00003nrx	Download File View File

Insights into anti-parallel microtubule crosslinking by PRC1, a conserved non-motor microtubule binding protein

Kapoor, T.M., Subramanian, R., Wilson-Kubalek, E.M., Arthur, C.P., Bick, M.J., Campbell, E.A., Darst, S.A., Milligan, R.A.

(2010) Cell 142: 433-443

Released	2010-08-18
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Homo sapiens
Macromolecule	Protein regulator of cytokinesis 1 (protein)

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3NRY \| pdb_00003nry	Download File View File

Insights into anti-parallel microtubule crosslinking by PRC1, a conserved microtubule binding protein

Kapoor, T.M., Subramanian, R., Wilson-Kubalek, E.M., Arthur, C.P., Bick, M.J., Campbell, E.A., Darst, S.A., Milligan, R.A.

(2010) Cell 142: 433-443

Released	2010-08-25
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	Protein regulator of cytokinesis 1 (protein)

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3ZYC \| pdb_00003zyc	Download File View File

DYNAMIN 1 GTPASE GED FUSION DIMER COMPLEXED WITH GMPPCP

Chappie, J.S., Mears, J.A., Fang, S., Leonard, M., Schmid, S.L., Milligan, R.A., Hinshaw, J.E., Dyda, F.

(2011) Cell 147: 209

Released	2011-10-12
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	DYNAMIN-1 (protein)
Unique Ligands	GCP, MG

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3ZYS \| pdb_00003zys	Download File View File

Human dynamin 1 deltaPRD polymer stabilized with GMPPCP

Chappie, J.S., Mears, J.A., Fang, S., Leonard, M., Schmid, S.L., Milligan, R.A., Hinshaw, J.E., Dyda, F.

(2011) Cell 147: 209

Released	2011-10-12
Method	ELECTRON MICROSCOPY 12.2 Å
Organisms	Homo sapiens
Macromolecule	DYNAMIN-1 (protein) INTERFERON-INDUCED GTP-BINDING PROTEIN MX1 (protein)

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4YLR \| pdb_00004ylr	Download File View File

Tubulin Glutamylase

Garnham, C.P., Vemu, A., Wilson-Kubalek, E.M., Yu, I., Szyk, A., Lander, G.C., Milligan, R.A., Roll-Mecak, A.

(2015) Cell 161: 1112-1123

Released	2015-06-17
Method	X-RAY DIFFRACTION 2.55 Å
Organisms	Homo sapiens
Macromolecule	Tubulin polyglutamylase TTLL7 (protein)
Unique Ligands	ADP

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4YLS \| pdb_00004yls	Download File View File

Tubulin Glutamylase

Garnham, C.P., Vemu, A., Wilson-Kubalek, E.M., Yu, I., Szyk, A., Lander, G.C., Milligan, R.A., Roll-Mecak, A.

(2015) Cell 161: 1112-1123

Released	2015-06-17
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Tubulin polyglutamylase TTLL7 (protein)
Unique Ligands	ANP

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6MLQ \| pdb_00006mlq	Download File View File

Cryo-EM structure of microtubule-bound Kif7 in the ADP state

Mani, N., Jiang, S., Wilson-Kubalek, E.M., Ku, P., Milligan, R.A., Subramanian, R.

(2019) Dev Cell 49: 711-730.e8

Released	2019-05-01
Method	ELECTRON MICROSCOPY 4.2 Å
Organisms	Homo sapiens Sus scrofa
Macromolecule	Kinesin-like protein KIF7 (protein) Tubulin alpha-1A chain (protein) Tubulin beta chain (protein)
Unique Ligands	ADP, GDP, GTP, MG, TA1

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6MLR \| pdb_00006mlr	Download File View File

Cryo-EM structure of microtubule-bound Kif7 in the AMPPNP state

Mani, N., Jiang, S., Wilson-Kubalek, E.M., Ku, P., Milligan, R.A., Subramanian, R.

(2019) Dev Cell 49: 711-730.e8

Released	2019-05-01
Method	ELECTRON MICROSCOPY 4.2 Å
Organisms	Homo sapiens Sus scrofa
Macromolecule	Kinesin-like protein KIF7 (protein) Tubulin alpha-1A chain (protein) Tubulin beta chain (protein)
Unique Ligands	ANP, GDP, GTP, TA1

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7RX0 \| pdb_00007rx0	Download File View File

Complex of AMPPNP-Kif7 and Gli2 Zinc-Finger domain bound to microtubules

Mani, N., Wilson-Kubalek, E.M., Haque, F., Freniere, C., Milligan, R.A., Subramanian, R.

(2022) Nat Cell Biol 24: 1088-1098

Released	2022-06-15
Method	ELECTRON MICROSCOPY 3.89 Å
Organisms	Homo sapiens Sus scrofa
Macromolecule	Kinesin-like protein KIF7 (protein) Tubulin alpha-1A chain (protein) Tubulin beta chain (protein) Zinc finger protein GLI2 (protein)
Unique Ligands	ANP, G2P, GTP, MG

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8G8F \| pdb_00008g8f	Download File View File

Human IMPDH2 mutant - L245P, treated with ATP, IMP, and NAD+; extended filament segment reconstruction

O'Neill, A.G., Kollman, J.M.

(2023) J Biological Chem 299: 105012-105012

Released	2023-04-19
Method	ELECTRON MICROSCOPY 2.6 Å
Organisms	Homo sapiens
Macromolecule	Inosine-5'-monophosphate dehydrogenase 2 (protein)
Unique Ligands	ATP, IMP, NAD

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8G9B \| pdb_00008g9b	Download File View File

Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; compressed filament segment reconstruction

O'Neill, A.G., Kollman, J.M.

(2023) J Biological Chem 299: 105012-105012

Released	2023-04-19
Method	ELECTRON MICROSCOPY 3 Å
Organisms	Homo sapiens
Macromolecule	Inosine-5'-monophosphate dehydrogenase 2 (protein)
Unique Ligands	ATP, GTP, IMP, NAD

1 to 13 of 13 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

2LYC | pdb_00002lyc

Structure of C-terminal domain of Ska1

3ERR | pdb_00003err

Microtubule binding domain from mouse cytoplasmic dynein as a fusion with seryl-tRNA synthetase

3NRX | pdb_00003nrx

Insights into anti-parallel microtubule crosslinking by PRC1, a conserved non-motor microtubule binding protein

3NRY | pdb_00003nry

Insights into anti-parallel microtubule crosslinking by PRC1, a conserved microtubule binding protein

3ZYC | pdb_00003zyc

DYNAMIN 1 GTPASE GED FUSION DIMER COMPLEXED WITH GMPPCP

3ZYS | pdb_00003zys

Human dynamin 1 deltaPRD polymer stabilized with GMPPCP

4YLR | pdb_00004ylr

Tubulin Glutamylase

4YLS | pdb_00004yls

Tubulin Glutamylase

6MLQ | pdb_00006mlq

Cryo-EM structure of microtubule-bound Kif7 in the ADP state

6MLR | pdb_00006mlr

Cryo-EM structure of microtubule-bound Kif7 in the AMPPNP state

7RX0 | pdb_00007rx0

Complex of AMPPNP-Kif7 and Gli2 Zinc-Finger domain bound to microtubules

8G8F | pdb_00008g8f

Human IMPDH2 mutant - L245P, treated with ATP, IMP, and NAD+; extended filament segment reconstruction

8G9B | pdb_00008g9b

Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; compressed filament segment reconstruction

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

2LYC | pdb_00002lyc

3ERR | pdb_00003err

3NRX | pdb_00003nrx

3NRY | pdb_00003nry

3ZYC | pdb_00003zyc

3ZYS | pdb_00003zys

4YLR | pdb_00004ylr

4YLS | pdb_00004yls

6MLQ | pdb_00006mlq

6MLR | pdb_00006mlr

7RX0 | pdb_00007rx0

8G8F | pdb_00008g8f

8G9B | pdb_00008g9b