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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Laeremans, T."

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Search Summary

This query matches 30 Structures.

Refinements

Structure Determination Methodology

experimental (30)

Scientific Name of Source Organism

	Homo sapiens (22)
	Lama glama (16)
	Mus musculus (6)
	Escherichia coli (2)
	Escherichia coli BL21 (2)
	synthetic construct (2)
	Camelus dromedarius (1)

Taxonomy

	Eukaryota (27)
	Bacteria (4)
	other sequences (2)

Experimental Method

	X-RAY DIFFRACTION (26)
	ELECTRON MICROSCOPY (4)

Polymer Entity Type

Protein (30)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (7)
	2.0 - 2.5 (12)
	2.5 - 3.0 (5)
	3.0 - 3.5 (2)
	> 4.5 (3)

Release Date

	2000 - 2004 (1)
	2010 - 2014 (14)
	2015 - 2019 (11)
	2020 - 2024 (4)

Enzyme Classification Name

	Hydrolases (16)
	Isomerases (6)

Membrane Protein Annotation

	MemProtMD (3)
	PDBTM (3)
	mpstruc (2)
	OPM (1)

Symmetry Type

	Asymmetric (25)
	Cyclic (4)
	Dihedral (1)

SCOP Classification

	All beta proteins (20)
	Artifacts (16)
	Alpha and beta proteins (a/b) (5)
	Alpha and beta proteins (a+b) (4)
	Membrane and cell surface proteins and peptides (1)

AllSelected

1 to 25 of 30 Structures

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1MVF \| pdb_00001mvf	Download File View File

MazE addiction antidote

Loris, R., Marianovsky, I., Lah, J., Laeremans, T., Engelberg-Kulka, H., Glaser, G., Muyldermans, S., Wyns, L.

(2003) J Biological Chem 278: 28252-28257

Released	2003-06-10
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Camelus dromedarius Escherichia coli
Macromolecule	PemI-like protein 1 (protein) immunoglobulin heavy chain variable region (protein)

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2YPW \| pdb_00002ypw	Download File View File

Atomic model for the N-terminus of TraO fitted in the full-length structure of the bacterial pKM101 type IV secretion system core complex

Rivera-Calzada, A., Fronzes, R., Savva, C.G., Chandran, V., Lian, P.W., Laeremans, T., Pardon, E., Steyaert, J., Remaut, H., Waksman, G., Orlova, E.V.

(2013) EMBO J 32: 1195

Released	2013-04-03
Method	ELECTRON MICROSCOPY 12.4 Å
Organisms	Escherichia coli
Macromolecule	TRAO (protein)

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3ZBI \| pdb_00003zbi	Download File View File

Fitting result in the O-layer of the subnanometer structure of the bacterial pKM101 type IV secretion system core complex digested with elastase

Rivera-Calzada, A., Fronzes, R., Savva, C.G., Chandran, V., Lian, P.W., Laeremans, T., Pardon, E., Steyaert, J., Remaut, H., Waksman, G., Orlova, E.V.

(2013) EMBO J 32: 1195

Released	2013-04-03
Method	ELECTRON MICROSCOPY 8.5 Å
Organisms	Escherichia coli BL21
Macromolecule	TRAF PROTEIN (protein) TRAN PROTEIN (protein) TRAO PROTEIN (protein)

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3ZBJ \| pdb_00003zbj	Download File View File

Fitting results in the I-layer of the subnanometer structure of the bacterial pKM101 type IV secretion system core complex digested with elastase

Rivera-Calzada, A., Fronzes, R., Savva, C.G., Chandran, V., Lian, P.W., Laeremans, T., Pardon, E., Steyaert, J., Remaut, H., Waksman, G., Orlova, E.V.

(2013) EMBO J 32: 1195

Released	2013-04-03
Method	ELECTRON MICROSCOPY 8.5 Å
Organisms	Escherichia coli BL21
Macromolecule	TRAO PROTEIN (protein)

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3ZKG \| pdb_00003zkg	Download File View File

BACE2 MUTANT APO STRUCTURE

Banner, D.W., Kuglstatter, A., Benz, J., Stihle, M., Ruf, A.

(2013) Acta Crystallogr D Biol Crystallogr 69: 1124

Released	2013-05-29
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	BETA-SECRETASE 2 (protein)
Unique Ligands	B3P

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3ZKI \| pdb_00003zki	Download File View File

BACE2 MUTANT STRUCTURE WITH LIGAND

Banner, D.W., Kuglstatter, A., Benz, J., Stihle, M., Ruf, A.

(2013) Acta Crystallogr D Biol Crystallogr 69: 1124

Released	2013-05-29
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	BETA-SECRETASE 2 (protein)
Unique Ligands	WZV

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3ZKM \| pdb_00003zkm	Download File View File

BACE2 FAB COMPLEX

Banner, D.W., Kuglstatter, A., Benz, J., Stihle, M., Ruf, A.

(2013) Acta Crystallogr D Biol Crystallogr 69: 1124

Released	2013-05-29
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	BETA-SECRETASE 2 (protein) FAB HEAVY CHAIN (protein) FAB LIGHT CHAIN (protein)
Unique Ligands	DMS, GOL, SO4

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3ZKN \| pdb_00003zkn	Download File View File

BACE2 FAB INHIBITOR COMPLEX

Banner, D.W., Kuglstatter, A., Benz, J., Stihle, M., Ruf, A.

(2013) Acta Crystallogr D Biol Crystallogr 69: 1124

Released	2013-05-29
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	BETA-SECRETASE 2 (protein) FAB HEAVY CHAIN (protein) FAB LIGHT CHAIN (protein)
Unique Ligands	DMS, GOL, SO4, WZV

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3ZKQ \| pdb_00003zkq	Download File View File

BACE2 XAPERONE COMPLEX

Banner, D.W., Kuglstatter, A., Benz, J., Stihle, M., Ruf, A.

(2013) Acta Crystallogr D Biol Crystallogr 69: 1124

Released	2013-05-29
Method	X-RAY DIFFRACTION 1.51 Å
Organisms	Homo sapiens Lama glama
Macromolecule	BETA-SECRETASE 2 (protein) XA4813 (protein)
Unique Ligands	B3P, CL

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3ZKS \| pdb_00003zks	Download File View File

BACE2 XAPERONE COMPLEX WITH INHIBITOR

Banner, D.W., Kuglstatter, A., Benz, J., Stihle, M., Ruf, A.

(2013) Acta Crystallogr D Biol Crystallogr 69: 1124

Released	2013-05-29
Method	X-RAY DIFFRACTION 2.11 Å
Organisms	Homo sapiens Lama glama
Macromolecule	BETA-SECRETASE 2 (protein) XA4813 (protein)
Unique Ligands	WZV

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3ZKX \| pdb_00003zkx	Download File View File

TERNARY BACE2 XAPERONE COMPLEX

Kuglstatter, A., Banner, D.W., Benz, J., Bertschinger, J., Burger, D., Cuppuleri, S., Debulpaep, M., Gast, A., Grabulovski, D., Gsell, B., Hilpert, H., Huber, W., Kusznir, E., Laeremans, T., Matile, H., Rufer, A., Schlatter, D., Steyeart, J., Stihle, M., Thoma, R., Weber, M., Ruf, A.

(2013) Acta Crystallogr D Biol Crystallogr 69: 1124

Released	2013-05-29
Method	X-RAY DIFFRACTION 2.37 Å
Organisms	Homo sapiens Lama glama
Macromolecule	BETA-SECRETASE 2 (protein) XA4813 (protein) XA4815 (protein)
Unique Ligands	CL, DMS

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3ZL7 \| pdb_00003zl7	Download File View File

BACE2 FYNOMER COMPLEX

Banner, D.W., Kuglstatter, A., Benz, J., Stihle, M., Ruf, A.

(2013) Acta Crystallogr D Biol Crystallogr 69: 1124

Released	2013-05-29
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Homo sapiens synthetic construct
Macromolecule	BETA-SECRETASE 2 (protein) FYNOMER 2B-H11 (protein)

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3ZOV \| pdb_00003zov	Download File View File

CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH CHEMICAL LIGAND

Banner, D.W., Kuglstatter, A., Benz, J., Stihle, M., Ruf, A.

(2013) Acta Crystallogr D Biol Crystallogr 69: 1124

Released	2013-05-29
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	BETA-SECRETASE 1 (protein)
Unique Ligands	DMS, NA, WZV

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4BEL \| pdb_00004bel	Download File View File

BACE2 XAPERONE COMPLEX

Banner, D.W., Kuglstatter, A., Benz, J., Stihle, M., Ruf, A.

(2013) Acta Crystallogr D Biol Crystallogr 69: 1124

Released	2013-05-29
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens Lama glama
Macromolecule	BETA-SECRETASE 2 (protein) XA4813 (protein)
Unique Ligands	B3P, CL

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4BFB \| pdb_00004bfb	Download File View File

BACE2 XAPERONE COMPLEX

Banner, D.W., Kuglstatter, A., Benz, J., Stihle, M., Ruf, A.

(2013) Acta Crystallogr D Biol Crystallogr 69: 1124

Released	2013-05-29
Method	X-RAY DIFFRACTION 2.21 Å
Organisms	Homo sapiens Lama glama
Macromolecule	BETA-SECRETASE 2 (protein) XA4813 (protein)
Unique Ligands	B3P

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5C1M \| pdb_00005c1m	Download File View File

Crystal structure of active mu-opioid receptor bound to the agonist BU72

Huang, W.J., Manglik, A., Venkatakrishnan, A.J., Laeremans, T., Feinberg, E.N., Sanborn, A.L., Kato, H.E., Livingston, K.E., Thorsen, T.S., Kling, R., Granier, S., Gmeiner, P., Husbands, S.M., Traynor, J.R., Weis, W.I., Steyaert, J., Dror, R.O., Kobilka, B.K.

(2015) Nature 524: 315-321

Released	2015-08-05
Method	X-RAY DIFFRACTION 2.07 Å
Organisms	Lama glama Mus musculus
Macromolecule	Mu-type opioid receptor (protein) Nanobody 39 (protein)
Unique Ligands	CLR, OLC, P6G, PO4, VF1

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5IKC \| pdb_00005ikc	Download File View File

X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN in complex with FAB

Ruf, A., Stihle, M., Benz, J., Thoma, R., Rudolph, M.G.

(2016) J Biological Chem 291: 16292-16306

Released	2016-05-18
Method	X-RAY DIFFRACTION 2.06 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Ighg protein (protein) MAb 6H10 light chain (protein) Neuronal migration protein doublecortin (protein)
Unique Ligands	CL

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5IN7 \| pdb_00005in7	Download File View File

X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN

Ruf, A., Benz, J., Burger, D., D'Arcy, B., Debulpaep, M., Di Lello, P., Fry, D., Huber, W., Kremer, T., Laeremans, T., Matile, H., Ross, A., Rudolph, M.G., Rufer, A.C., Sharma, A., Steinmetz, M.O., Steyaert, J., Schoch, G., Stihle, M., Thoma, R.

(2016) J Biological Chem 291: 16292-16306

Released	2016-03-23
Method	X-RAY DIFFRACTION 2.48 Å
Organisms	Homo sapiens
Macromolecule	Neuronal migration protein doublecortin (protein)

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5IO9 \| pdb_00005io9	Download File View File

X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN

(2016) J Biological Chem 291: 16292-16306

Released	2016-03-23
Method	X-RAY DIFFRACTION 1.3 Å
Organisms	Homo sapiens
Macromolecule	Neuronal migration protein doublecortin (protein)

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5IOI \| pdb_00005ioi	Download File View File

X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN

(2016) J Biological Chem 291: 16292-16306

Released	2016-03-23
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	Neuronal migration protein doublecortin (protein)

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5IP4 \| pdb_00005ip4	Download File View File

X-RAY STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN

(2016) J Biological Chem 291: 16292-16306

Released	2016-05-18
Method	X-RAY DIFFRACTION 1.81 Å
Organisms	Homo sapiens Lama glama
Macromolecule	Neuronal migration protein doublecortin (protein) XA4551 NANOBODY AGAINST C-DCX (protein)

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6GJQ \| pdb_00006gjq	Download File View File

human NBD1 of CFTR in complex with nanobody T27

Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C.

(2019) Nat Commun 10: 2636-2636

Released	2019-06-19
Method	X-RAY DIFFRACTION 2.49 Å
Organisms	Homo sapiens Lama glama
Macromolecule	Cystic fibrosis transmembrane conductance regulator (protein) Nanobody T27 (protein)
Unique Ligands	ATP

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6GJS \| pdb_00006gjs	Download File View File

Human NBD1 of CFTR in complex with nanobodies D12 and T4

Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C.

(2019) Nat Commun 10: 2636-2636

Released	2019-06-26
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens Lama glama
Macromolecule	Cystic fibrosis transmembrane conductance regulator (protein) Nanobody D12 (protein) Nanobody T4 (protein)
Unique Ligands	ATP, MG

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6GJU \| pdb_00006gju	Download File View File

human NBD1 of CFTR in complex with nanobodies T2a and T4

Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C.

(2019) Nat Commun 10: 2636-2636

Released	2019-06-26
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens Lama glama
Macromolecule	Cystic fibrosis transmembrane conductance regulator (protein) Nanobody T2a (protein) Nanobody T4 (protein)
Unique Ligands	GOL, PEG

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6GK4 \| pdb_00006gk4	Download File View File

Human NBD1 of CFTR in complex with nanobodies D12 and T8

Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C.

(2019) Nat Commun 10: 2636-2636

Released	2019-06-19
Method	X-RAY DIFFRACTION 2.91 Å
Organisms	Homo sapiens Lama glama
Macromolecule	Cystic fibrosis transmembrane conductance regulator (protein) Nanobody D12 (protein) Nanobody T8 (protein)
Unique Ligands	ATP, GOL, MG

1 to 25 of 30 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1MVF | pdb_00001mvf

2YPW | pdb_00002ypw

3ZBI | pdb_00003zbi

3ZBJ | pdb_00003zbj

3ZKG | pdb_00003zkg

3ZKI | pdb_00003zki

3ZKM | pdb_00003zkm

3ZKN | pdb_00003zkn

3ZKQ | pdb_00003zkq

3ZKS | pdb_00003zks

3ZKX | pdb_00003zkx

3ZL7 | pdb_00003zl7

3ZOV | pdb_00003zov

4BEL | pdb_00004bel

4BFB | pdb_00004bfb

5C1M | pdb_00005c1m

5IKC | pdb_00005ikc

5IN7 | pdb_00005in7

5IO9 | pdb_00005io9

5IOI | pdb_00005ioi

5IP4 | pdb_00005ip4

6GJQ | pdb_00006gjq

6GJS | pdb_00006gjs

6GJU | pdb_00006gju

6GK4 | pdb_00006gk4