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232,829 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Kreienkamp, H.J."

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Search Summary

This query matches 31 Structures.

Refinements

Structure Determination Methodology

experimental (31)

Scientific Name of Source Organism

	Homo sapiens (25)
	Gallus gallus (5)
	Mus musculus (5)
	Amanita phalloides (1)

Taxonomy

Eukaryota (31)

Experimental Method

	X-RAY DIFFRACTION (26)
	SOLUTION NMR (4)
	ELECTRON MICROSCOPY (1)

Polymer Entity Type

Protein (31)

Refinement Resolution (Å)

	1.0 - 1.5 (3)
	1.5 - 2.0 (8)
	2.0 - 2.5 (8)
	2.5 - 3.0 (7)
	3.5 - 4.0 (1)

Release Date

	2000 - 2004 (4)
	2005 - 2009 (6)
	2010 - 2014 (14)
	2015 - 2019 (2)
	2020 - 2024 (5)

Enzyme Classification Name

	Transferases (10)
	Hydrolases (2)

Symmetry Type

	Asymmetric (30)
	Cyclic (1)

SCOP Classification

	All beta proteins (7)
	All alpha proteins (4)
	Alpha and beta proteins (a+b) (5)
	Artifacts (2)
	Alpha and beta proteins (a/b) (1)
	Peptides (1)

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1 to 25 of 31 Structures

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1MIX	Download File View File

Crystal structure of a FERM domain of Talin

Garcia-Alvarez, B., de Pereda, J.M., Calderwood, D.A., Ulmer, T.S., Critchley, D., Campbell, I.D., Ginsberg, M.H., Liddington, R.C.

(2003) Mol Cell 11: 49-58

Released	2003-01-28
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Gallus gallus
Macromolecule	Talin (protein)

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1MIZ	Download File View File

Crystal structure of an integrin beta3-talin chimera

Garcia-Alvarez, B., de Pereda, J.M., Calderwood, D.A., Ulmer, T.S., Critchley, D., Campbell, I.D., Ginsberg, M.H., Liddington, R.C.

(2003) Mol Cell 11: 49-58

Released	2003-01-28
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Gallus gallus Homo sapiens
Macromolecule	TALIN (protein) integrin beta3 (protein)

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1MK7	Download File View File

CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA

Garcia-Alvarez, B., De Pereda, J.M., Calderwood, D.A., Ulmer, T.S., Critchley, D., Campbell, I.D., Ginsberg, M.H., Liddington, R.C.

(2003) Mol Cell 11: 49-58

Released	2003-01-28
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Gallus gallus Homo sapiens
Macromolecule	Integrin Beta3 (protein) TALIN (protein)

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1MK9	Download File View File

CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA

Garcia-Alvarez, B., De Pereda, J.M., Calderwood, D.A., Ulmer, T.S., Critchley, D., Campbell, I.D., Ginsberg, M.H., Liddington, R.C.

(2003) Mol Cell 11: 49-58

Released	2003-01-28
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Gallus gallus Homo sapiens
Macromolecule	Integrin Beta3 (protein) TALIN (protein)

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2BRQ	Download File View File

Crystal structure of the filamin A repeat 21 complexed with the integrin beta7 cytoplasmic tail peptide

Kiema, T.-R., Ylanne, J.

(2006) Mol Cell 21: 337

Released	2006-02-07
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	FILAMIN A (protein) INTEGRIN BETA-7 SUBUNIT (protein)
Unique Ligands	GOL, GSH

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2J3S	Download File View File

Crystal structure of the human filamin A Ig domains 19 to 21

Kiema, T.-R., Ylanne, J.

(2007) EMBO J 26: 3993

Released	2007-10-16
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	FILAMIN-A (protein)
Unique Ligands	BR, DIO, GOL

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2KC1	Download File View File

NMR structure of the F0 domain (residues 0-85) of the talin ferm domain

Goult, B.T., Elliott, P.R., Roberts, G.C.K., Critchley, D.R., Barsukov, I.L.

(2010) EMBO J 29: 1069-1080

Released	2010-01-19
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	MKIAA1027 protein (protein)

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2KC2	Download File View File

NMR structure of the F1 domain (residues 86-202) of the talin

Goult, B.T., Elliott, P.R., Roberts, G.C.K., Critchely, D.R., Barsukov, I.L.

(2010) EMBO J 29: 1069-1080

Released	2010-01-19
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	Talin-1 (protein)

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2KMA	Download File View File

NMR structure of the F0F1 double domain (residues 1-202) of the talin ferm domain

Goult, B.T., Elliott, P.R., Bate, N., Roberts, G.C., Critchley, D.R., Barsukov, I.L.

(2010) EMBO J

Released	2010-03-02
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	Talin 1 (protein)

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2KMC	Download File View File

Solution Structure of the N-terminal domain of kindlin-1

Goult, B.T., Bate, N., Roberts, G.C., Barsukov, I.L., Critchley, D.R.

(2009) J Mol Biology 394: 944-956

Released	2009-10-06
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	Fermitin family homolog 1 (protein)

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2W0P	Download File View File

Crystal structure of the filamin A repeat 21 complexed with the migfilin peptide

Ruskamo, S., Ylanne, J.

(2008) J Biological Chem 283: 35154

Released	2008-09-30
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	FILAMIN-A (protein) FILAMIN-BINDING LIM PROTEIN 1 (protein)
Unique Ligands	SO4

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3F6Q	Download File View File

Crystal structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain

Chiswell, B.P., Calderwood, D.A., Boggon, T.J.

(2008) Proc Natl Acad Sci U S A 105: 20677-20682

Released	2008-12-02
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Homo sapiens
Macromolecule	Integrin-linked protein kinase (protein) LIM and senescent cell antigen-like-containing domain protein 1 (protein)
Unique Ligands	IOD, PO4, ZN

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3IXE	Download File View File

Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase

Chiswell, B.P., Stiegler, A.L., Boggon, T.J., Calderwood, D.A.

(2010) J Struct Biol 170: 157-163

Released	2009-12-15
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Integrin-linked protein kinase (protein) LIM and senescent cell antigen-like-containing domain protein 2 (protein)
Unique Ligands	ZN

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4BBK	Download File View File

Structural and functional characterisation of the kindlin-1 pleckstrin homology domain

Yates, L.A., Lumb, C.N., Brahme, N.N., Zalyte, R., Bird, L.E., De Colibus, L., Owens, R.J., Calderwood, D.A., Sansom, M.S.P., Gilbert, R.J.C.

(2012) J Biological Chem 287: 43246

Released	2012-11-14
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Mus musculus
Macromolecule	FERMITIN FAMILY HOMOLOG 1 (protein)
Unique Ligands	GOL

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4DX8	Download File View File

ICAP1 in complex with KRIT1 N-terminus

Liu, W., Draheim, K., Zhang, R., Calderwood, D.A., Boggon, T.J.

(2013) Mol Cell 49: 719-729

Released	2013-01-09
Method	X-RAY DIFFRACTION 2.54 Å
Organisms	Homo sapiens
Macromolecule	Integrin beta-1-binding protein 1 (protein) Krev interaction trapped protein 1 (protein)
Unique Ligands	BR

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4DX9	Download File View File

ICAP1 in complex with integrin beta 1 cytoplasmic tail

Liu, W., Draheim, K., Zhang, R., Calderwood, D.A., Boggon, T.J.

(2013) Mol Cell 49: 719-729

Released	2013-01-09
Method	X-RAY DIFFRACTION 2.99 Å
Organisms	Homo sapiens
Macromolecule	Integrin beta-1 (protein) Integrin beta-1-binding protein 1 (protein)

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4DXA	Download File View File

Co-crystal structure of Rap1 in complex with KRIT1

Li, X., Zhang, R., Boggon, T.J.

(2012) J Biological Chem 287: 22317-22327

Released	2012-05-16
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens
Macromolecule	Krev interaction trapped protein 1 (protein) Ras-related protein Rap-1b (protein)
Unique Ligands	GSP, MG

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4EDL	Download File View File

Crystal structure of beta-parvin CH2 domain

Stiegler, A.L., Draheim, K.M., Li, X., Chayen, N.E., Calderwood, D.A., Boggon, T.J.

(2012) J Biological Chem 287: 32566-32577

Released	2012-08-08
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Beta-parvin (protein)
Unique Ligands	EDO

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4EDM	Download File View File

Crystal structure of beta-parvin CH2 domain

Stiegler, A.L., Draheim, K.M., Li, X., Chayen, N.E., Calderwood, D.A., Boggon, T.J.

(2012) J Biological Chem 287: 32566-32577

Released	2012-08-08
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	Beta-parvin (protein)
Unique Ligands	EDO

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4EDN	Download File View File

Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif

Stiegler, A.L., Draheim, K.M., Li, X., Chayen, N.E., Calderwood, D.A., Boggon, T.J.

(2012) J Biological Chem 287: 32566-32577

Released	2012-08-08
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	Beta-parvin (protein) Paxillin (protein)
Unique Ligands	SO4

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4HI8	Download File View File

Structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at high energy, wavelength 0.32800

Stiegler, A.L., Jakoncic, J., Stojanoff, V., Chiswell, B.P., Calderwood, D.A., Boggon, T.J.

To be published

Released	2013-12-11
Method	X-RAY DIFFRACTION 1.203 Å
Organisms	Homo sapiens
Macromolecule	Integrin-linked protein kinase (protein) LIM and senescent cell antigen-like-containing domain protein 1 (protein)
Unique Ligands	PO4, ZN

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4HI9	Download File View File

1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at wavelength 0.91974

Stiegler, A.L., Jakoncic, J., Stojanoff, V., Chiswell, B.P., Calderwood, D.A., Boggon, T.J.

To be published

Released	2013-12-11
Method	X-RAY DIFFRACTION 1.203 Å
Organisms	Homo sapiens
Macromolecule	Integrin-linked protein kinase (protein) LIM and senescent cell antigen-like-containing domain protein 1 (protein)
Unique Ligands	IOD, PO4, ZN

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4KS7	Download File View File

PAK6 kinase domain in complex with PF-3758309

Gao, J., Boggon, T.J.

(2013) PLoS One 8: e77818-e77818

Released	2013-09-11
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase PAK 6 (protein)
Unique Ligands	7KC, IPA

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4KS8	Download File View File

PAK6 kinase domain in complex with sunitinib

Gao, J., Boggon, T.J.

(2013) PLoS One 8: e77818-e77818

Released	2013-09-11
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase PAK 6 (protein)
Unique Ligands	B49

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4TVQ	Download File View File

CCM3 in complex with CCM2 LD-like motif

Li, X., Zhang, R., Fisher, O.S., Boggon, T.J.

(2015) J Cell Biol 208: 987-1001

Released	2015-03-25
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	Cerebral cavernous malformations 2 protein (protein) Cerebral cavernous malformations 3 protein (protein)