RCSB PDB: Search

Warning You are using a web browser that we do not support. Our website will not work properly. Please update to a newer version or download a new web browser, such as Chrome or Firefox.

Help

Help

RCSB PDB

Deposit
- PDBx/mmCIF file
- pdb_extract
- SF-Tool
- Ligand Expo
- MAXIT
- Validation Server
- Validation API
- Information for Journals
- Validation Task Forces
- wwPDB OneDep System
- PDB-IHM
Search
Visualize
Analyze
Download
Learn
- Training Courses
- Guide to PDB Data
- Molecule of the Month
- Educational Resources
- Curricula
- Browse
- News
- SciArt Galleries
- Irving Geis
- David Goodsell
About
Careers
COVID-19

233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

	Include CSM
Advanced Search \| Browse Annotations		Help

Search
Query History
Browse Annotations
MyPDB

QUERY: Citation Author = "Gu, W."

MyPDB Login

Search API

Advanced Search Query Builder

Help

Full Text

Structure Attributes

Help

NOT

Count

Add Subquery

Chemical Attributes

Sequence Similarity

Sequence Motif

Structure Similarity

Structure Motif

Chemical Similarity

Return

grouped by

Include Computed Structure Models (CSM)

Count

Clear

Search Summary

This query matches 100 Structures.

Refinements

Structure Determination Methodology

experimental (100)

Scientific Name of Source Organism

	Homo sapiens (59)
	Human immunodeficiency virus type 1 BH10 (18)
	Influenza A virus (A/Beijing/39/1975(H3N2)) (5)
	Mus musculus (5)
	synthetic construct (5)
	Drosophila melanogaster (4)
	Escherichia coli (3)
	Influenza A virus (A/Victoria/3/1975(H3N2)) (3)
	Methanothermococcus thermolithotrophicus DSM 2095 (3)
	Thermochaetoides thermophila DSM 1495 (3)

More...

Taxonomy

	Eukaryota (70)
	Riboviria (27)
	Bacteria (16)
	Archaea (5)
	other sequences (5)
	Varidnaviria (1)

Experimental Method

	X-RAY DIFFRACTION (86)
	ELECTRON MICROSCOPY (11)
	SOLUTION NMR (3)

Polymer Entity Type

	Protein (97)
	DNA (21)

Refinement Resolution (Å)

	1.0 - 1.5 (2)
	1.5 - 2.0 (27)
	2.0 - 2.5 (20)
	2.5 - 3.0 (24)
	3.0 - 3.5 (21)
	3.5 - 4.0 (2)
	> 4.5 (1)

Release Date

	2000 - 2004 (3)
	2005 - 2009 (5)
	2010 - 2014 (5)
	2015 - 2019 (13)
	2020 - 2024 (71)
	2025 - 2029 (3)

Enzyme Classification Name

	Hydrolases (65)
	Transferases (25)
	Oxidoreductases (7)
	Lyases (2)
	Isomerases (1)

Membrane Protein Annotation

	PDBTM (4)
	MemProtMD (2)
	OPM (1)

Symmetry Type

	Asymmetric (63)
	Cyclic (31)
	Helical (4)
	Dihedral (1)

SCOP Classification

	Alpha and beta proteins (a+b) (2)
	All beta proteins (2)
	All alpha proteins (1)

AllSelected

1 to 25 of 100 Structures

Page 1 of 4

Sort by

Explore in 3D

1NB8 \| pdb_00001nb8	Download File View File

Structure of the catalytic domain of USP7 (HAUSP)

Hu, M., Li, P., Li, M., Li, W., Yao, T., Wu, J.-W., Gu, W., Cohen, R.E., Shi, Y.

(2002) Cell 111: 1041-1054

Released	2003-01-07
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Ubiquitin carboxyl-terminal hydrolase 7 (protein)

Explore in 3D

1NBF \| pdb_00001nbf	Download File View File

Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde

Hu, M., Li, P., Li, M., Li, W., Yao, T., Wu, J.-W., Gu, W., Cohen, R.E., Shi, Y.

(2002) Cell 111: 1041-1054

Released	2003-01-07
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Ubiquitin aldehyde (protein) Ubiquitin carboxyl-terminal hydrolase 7 (protein)

Explore in 3D

1X81 \| pdb_00001x81	Download File View File

Farnesyl transferase structure of Jansen compound

Li, Q., Claiborne, A., Li, T., Hasvold, L., Stoll, V.S., Muchmore, S., Jakob, C.G., Gu, W., Cohen, J., Hutchins, C., Frost, D., Rosenberg, S.H., Sham, H.L.

(2004) Bioorg Med Chem Lett 14: 5367-5370

Released	2004-12-21
Method	X-RAY DIFFRACTION 3.5 Å
Organisms	Rattus norvegicus
Macromolecule	Protein farnesyltransferase beta subunit (protein) Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit (protein)
Unique Ligands	JAN, ZN

Explore in 3D

2F1W \| pdb_00002f1w	Download File View File

Crystal structure of the TRAF-like domain of HAUSP/USP7

Hu, M., Gu, L., Jeffrey, P.D., Shi, Y.

(2006) PLoS Biol 4: e27-e27

Released	2006-02-07
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Homo sapiens
Macromolecule	Ubiquitin carboxyl-terminal hydrolase 7 (protein)
Unique Ligands	CA

Explore in 3D

2F1X \| pdb_00002f1x	Download File View File

Crystal structure of the TRAF-like domain of HAUSP/USP7 bound to a p53 peptide

Hu, M., Gu, L., Jeffrey, P.D., Shi, Y.

(2006) PLoS Biol 4: e27-e27

Released	2006-02-07
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	HAUSP/USP7 (protein)

Explore in 3D

2F1Y \| pdb_00002f1y	Download File View File

Crystal structure of the TRAF-like domain of HAUSP/USP7 bound to a MDM2 peptide

Hu, M., Gu, L., Jeffrey, P.D., Shi, Y.

(2006) PLoS Biol 4: e27-e27

Released	2006-02-07
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	HAUSP/USP7 (protein)

Explore in 3D

2F1Z \| pdb_00002f1z	Download File View File

Crystal structure of HAUSP

Hu, M., Gu, L., Jeffrey, P.D., Shi, Y.

(2006) PLoS Biol 4: e27-e27

Released	2006-02-07
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Homo sapiens
Macromolecule	Ubiquitin carboxyl-terminal hydrolase 7 (protein)

Explore in 3D

2OSE \| pdb_00002ose	Download File View File

Crystal Structure of the Mimivirus Cyclophilin

Eisenmesser, E.Z., Thai, V., Renesto, P., Raoult, D.

(2008) J Mol Biology 378: 71-86

Released	2007-12-18
Method	X-RAY DIFFRACTION 2.04 Å
Organisms	Mimivirus
Macromolecule	Probable peptidyl-prolyl cis-trans isomerase (protein)
Unique Ligands	CL

Explore in 3D

3NX1 \| pdb_00003nx1	Download File View File

Crystal structure of Enterobacter sp. Px6-4 Ferulic Acid Decarboxylase

Gu, W., Yang, J.K., Lou, Z.Y., Meng, Z.H., Zhang, K.-Q.

(2011) PLoS One 6: e16262-e16262

Released	2011-02-16
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Enterobacter sp. Px6-4
Macromolecule	Ferulic acid decarboxylase (protein)

Explore in 3D

3NX2 \| pdb_00003nx2	Download File View File

Enterobacter sp. Px6-4 Ferulic Acid Decarboxylase in complex with substrate analogues

Gu, W., Yang, J.K., Lou, Z.Y., Meng, Z.H., Zhang, K.-Q.

(2011) PLoS One 6: e16262-e16262

Released	2011-02-16
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Enterobacter sp. Px6-4
Macromolecule	Ferulic acid decarboxylase (protein)
Unique Ligands	FER

Explore in 3D

4NCE \| pdb_00004nce	Download File View File

Influenza polymerase basic protein 2 (PB2) bound to 7-methyl-GTP

Jacobs, M.D.

(2014) J Med Chem 57: 6668-6678

Released	2014-07-30
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Influenza A virus (A/Victoria/3/1975(H3N2))
Macromolecule	Polymerase basic protein 2 (protein)
Unique Ligands	11H, MGT

Explore in 3D

4NCM \| pdb_00004ncm	Download File View File

Influenza polymerase basic protein 2 (PB2) bound to a small-molecule inhibitor

Jacobs, M.D.

(2014) J Med Chem 57: 6668-6678

Released	2014-07-30
Method	X-RAY DIFFRACTION 2.82 Å
Organisms	Influenza A virus (A/Victoria/3/1975(H3N2))
Macromolecule	Polymerase basic protein 2 (protein)
Unique Ligands	704

Explore in 3D

4P1U \| pdb_00004p1u	Download File View File

Influenza A (flu) virus polymerase basic protein 2 (PB2) bound to VX787, an azaindole inhibitor

Jacobs, M.D.

(2014) J Med Chem 57: 6668-6678

Released	2014-07-30
Method	X-RAY DIFFRACTION 2.52 Å
Organisms	Influenza A virus (A/Victoria/3/1975(H3N2))
Macromolecule	Polymerase basic protein 2 (protein)
Unique Ligands	21G

Explore in 3D

4YD0 \| pdb_00004yd0	Download File View File

Influenza polymerase basic protein 2 (PB2) bound to an azaindole-tetrazole inhibitor

Jacobs, M.D.

(2015) Bioorg Med Chem Lett 25: 1990-1994

Released	2015-04-15
Method	X-RAY DIFFRACTION 2.62 Å
Organisms	Influenza A virus (A/Beijing/39/1975(H3N2))
Macromolecule	Polymerase basic protein 2 (protein)
Unique Ligands	4EW

Explore in 3D

5BUH \| pdb_00005buh	Download File View File

Influenza PB2 bound to a hydroxymethyl azaindole inhibitor

Jacobs, M.D.

(2017) ACS Med Chem Lett 8: 261-265

Released	2016-06-08
Method	X-RAY DIFFRACTION 2.55 Å
Organisms	Influenza A virus (A/Beijing/39/1975(H3N2))
Macromolecule	Polymerase basic protein 2 (protein)
Unique Ligands	4V7

Explore in 3D

5F79 \| pdb_00005f79	Download File View File

Influenza PB2 bound to an azaindole inhibitor

Jacobs, M.D.

(2017) ACS Med Chem Lett 8: 261-265

Released	2016-12-07
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Influenza A virus (A/Beijing/39/1975(H3N2))
Macromolecule	Polymerase basic protein 2 (protein)
Unique Ligands	4V7

Explore in 3D

5JUN \| pdb_00005jun	Download File View File

PB2 bound to an azaindole inhibitor

Jacobs, M.D.

(2017) ACS Med Chem Lett 8: 256-260

Released	2017-05-17
Method	X-RAY DIFFRACTION 2.69 Å
Organisms	Influenza A virus (A/Beijing/39/1975(H3N2))
Macromolecule	Polymerase basic protein 2 (protein)
Unique Ligands	6NU

Explore in 3D

5JUR \| pdb_00005jur	Download File View File

PB2 bound to an azaindole inhibitor

Jacobs, M.D.

(2017) ACS Med Chem Lett 8: 256-260

Released	2017-03-01
Method	X-RAY DIFFRACTION 2.93 Å
Organisms	Influenza A virus (A/Beijing/39/1975(H3N2))
Macromolecule	Polymerase basic protein 2 (protein)
Unique Ligands	6NS

Explore in 3D

6O0Q \| pdb_00006o0q	Download File View File

Crystal structure of the TIR domain from human SARM1 in complex with ribose

Horsefield, S., Burdett, H., Zhang, X., Manik, M.K., Shi, Y., Chen, J., Tiancong, Q., Gilley, J., Lai, J., Gu, W., Rank, M., Deerain, N., Casey, L., Ericsson, D.J., Foley, G., Hughes, R.O., Bosanac, T., von Itzstein, M., Rathjen, J.P., Nanson, J.D., Boden, M., Dry, I.B., Williams, S.J., Staskawicz, B.J., Coleman, M.P., Ve, T., Dodds, P.N., Kobe, B.

(2019) Science 365: 793-799

Released	2019-09-04
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Sterile alpha and TIR motif-containing protein 1 (protein)
Unique Ligands	BDR, CL

Explore in 3D

6O0R \| pdb_00006o0r	Download File View File

Crystal structure of the TIR domain from human SARM1 in complex with glycerol

(2019) Science 365: 793-799

Released	2019-09-04
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Sterile alpha and TIR motif-containing protein 1 (protein)
Unique Ligands	GOL

Explore in 3D

6O0S \| pdb_00006o0s	Download File View File

Crystal structure of the tandem SAM domains from human SARM1

(2019) Science 365: 793-799

Released	2019-09-04
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	Sterile alpha and TIR motif-containing protein 1 (protein)

Explore in 3D

6O0T \| pdb_00006o0t	Download File View File

Crystal structure of selenomethionine labelled tandem SAM domains (L446M:L505M:L523M mutant) from human SARM1

(2019) Science 365: 793-799

Released	2019-09-04
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	Sterile alpha and TIR motif-containing protein 1 (protein)

Explore in 3D

6O0U \| pdb_00006o0u	Download File View File

Crystal structure of the TIR domain H685A mutant from human SARM1

Horsefield, S., Burdett, H., Zhang, X., Manik, M.K., Shi, Y., Chen, J., Tiancong, Q., Gilley, J., Lai, J., Gu, W., Rank, M., Casey, L., Ericsson, D.J., Foley, G., Hughes, R.O., Bosanac, T., von Itzstein, M., Rathjen, J.P., Nanson, J.D., Boden, M., Dry, I.B., Williams, S.J., Staskawicz, B.J., Coleman, M.P., Ve, T., Dodds, P.N., Kobe, B.

(2019) Science 365: 793-799

Released	2019-09-04
Method	X-RAY DIFFRACTION 3.03 Å
Organisms	Homo sapiens
Macromolecule	Sterile alpha and TIR motif-containing protein 1 (protein)

Explore in 3D

6O0V \| pdb_00006o0v	Download File View File

Crystal structure of the TIR domain G601P mutant from human SARM1, crystal form 2

(2019) Science 365: 793-799

Released	2019-09-04
Method	X-RAY DIFFRACTION 2.07 Å
Organisms	Homo sapiens
Macromolecule	Sterile alpha and TIR motif-containing protein 1 (protein)
Unique Ligands	CL, MES

Explore in 3D

6O0W \| pdb_00006o0w	Download File View File

Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1 in complex with NADP+ and Bis-Tris

(2019) Science 365: 793-799

Released	2019-09-04
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Vitis rotundifolia
Macromolecule	TIR-NB-LRR type resistance protein RUN1 (protein)
Unique Ligands	A2P, BTB

1 to 25 of 100 Structures

Page 1 of 4

Sort by

About
About Us
Citing Us
Publications
Team
Careers
Usage & Privacy

Support
Contact Us
Help
Website FAQ
Glossary
Service Status

RCSB PDB is hosted by

RCSB PDB is a member of the

RCSB Partners
Nucleic Acid Knowledgebase

wwPDB Partners
RCSB PDB
PDBe
PDBj
BMRB
EMDB

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

Prepare Data

Validate Data

Deposit Data

Help and Resources

Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1NB8 | pdb_00001nb8

1NBF | pdb_00001nbf

1X81 | pdb_00001x81

2F1W | pdb_00002f1w

2F1X | pdb_00002f1x

2F1Y | pdb_00002f1y

2F1Z | pdb_00002f1z

2OSE | pdb_00002ose

3NX1 | pdb_00003nx1

3NX2 | pdb_00003nx2

4NCE | pdb_00004nce

4NCM | pdb_00004ncm

4P1U | pdb_00004p1u

4YD0 | pdb_00004yd0

5BUH | pdb_00005buh

5F79 | pdb_00005f79

5JUN | pdb_00005jun

5JUR | pdb_00005jur

6O0Q | pdb_00006o0q

6O0R | pdb_00006o0r

6O0S | pdb_00006o0s

6O0T | pdb_00006o0t

6O0U | pdb_00006o0u

6O0V | pdb_00006o0v

6O0W | pdb_00006o0w