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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Ghirlando, R."

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Search Summary

This query matches 123 Structures.

Refinements

Structure Determination Methodology

experimental (123)

Scientific Name of Source Organism

	Homo sapiens (42)
	Severe acute respiratory syndrome coronavirus 2 (16)
	Escherichia coli (13)
	Mus musculus (10)
	Saccharomyces cerevisiae (9)
	Human immunodeficiency virus 1 (8)
	Drosophila melanogaster (6)
	synthetic construct (6)
	Escherichia coli K-12 (5)
	Neisseria gonorrhoeae (4)

More...

Taxonomy

	Eukaryota (63)
	Bacteria (38)
	Riboviria (27)
	other sequences (6)
	Eukaryota (eukaryotes) (2)
	Archaea (1)

Experimental Method

	X-RAY DIFFRACTION (81)
	SOLUTION NMR (29)
	ELECTRON MICROSCOPY (12)
	SOLUTION SCATTERING (6)
	SOLID-STATE NMR (1)

Polymer Entity Type

	Protein (123)
	DNA (27)
	RNA (6)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (16)
	2.0 - 2.5 (31)
	2.5 - 3.0 (24)
	3.0 - 3.5 (8)
	3.5 - 4.0 (11)
	> 4.5 (2)

Release Date

	1995 - 1999 (4)
	2000 - 2004 (9)
	2005 - 2009 (33)
	2010 - 2014 (19)
	2015 - 2019 (17)
	2020 - 2024 (40)
	2025 - 2029 (1)

Enzyme Classification Name

	Transferases (18)
	Hydrolases (27)
	Ligases (1)

Membrane Protein Annotation

	OPM (5)
	MemProtMD (3)
	PDBTM (3)
	mpstruc (2)

Symmetry Type

	Asymmetric (68)
	Cyclic (57)
	Dihedral (8)
	Helical (1)

SCOP Classification

	All alpha proteins (27)
	Alpha and beta proteins (a/b) (7)
	Alpha and beta proteins (a+b) (15)
	All beta proteins (16)
	Artifacts (11)
	Coiled coil proteins (1)

AllSelected

1 to 25 of 123 Structures

Page 1 of 5

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1FU1 \| pdb_00001fu1	Download File View File

CRYSTAL STRUCTURE OF HUMAN XRCC4

Junop, M., Modesti, M., Guarne, A., Gellert, M., Yang, W.

(2000) EMBO J 19: 5962-5970

Released	2000-12-11
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	DNA REPAIR PROTEIN XRCC4 (protein)
Unique Ligands	ACY

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1GJJ \| pdb_00001gjj	Download File View File

N-TERMINAL CONSTANT REGION OF THE NUCLEAR ENVELOPE PROTEIN LAP2

Clore, G.M., Cai, M.

(2001) EMBO J 20: 4399-4407

Released	2003-06-24
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	LAP2 (protein)

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1IB1 \| pdb_00001ib1	Download File View File

CRYSTAL STRUCTURE OF THE 14-3-3 ZETA:SEROTONIN N-ACETYLTRANSFERASE COMPLEX

Obsil, T., Ghirlando, R., Klein, D.C., Ganguly, S., Dyda, F.

(2001) Cell 105: 257-267

Released	2001-05-02
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens Ovis aries
Macromolecule	14-3-3 ZETA ISOFORM (protein) SEROTONIN N-ACETYLTRANSFERASE (protein)
Unique Ligands	COT

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1MN3 \| pdb_00001mn3	Download File View File

Cue domain of yeast Vps9p

Prag, G., Misra, S., Jones, E., Ghirlando, R., Davies, B.A., Horazdovsky, B.F., Hurley, J.H.

(2003) Cell 113: 609-620

Released	2003-06-10
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Vacuolar protein sorting-associated protein VPS9 (protein)

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1NRV \| pdb_00001nrv	Download File View File

Crystal structure of the SH2 domain of Grb10

Stein, E.G., Hubbard, S.R.

(2003) J Biological Chem 278: 13257-13264

Released	2003-04-15
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Homo sapiens
Macromolecule	Growth factor receptor-bound protein 10 (protein)

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1P3Q \| pdb_00001p3q	Download File View File

Mechanism of Ubiquitin Recognition by the CUE Domain of VPS9

Prag, G., Misra, S., Jones, E.A., Ghirlando, R., Davies, B.A., Horazdovsky, B.F., Hurley, J.H.

(2003) Cell 113: 609-620

Released	2003-06-24
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Bos taurus Saccharomyces cerevisiae
Macromolecule	Ubiquitin (protein) Vacuolar protein sorting-associated protein VPS9 (protein)

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1QCK \| pdb_00001qck	Download File View File

SOLUTION STRUCTURE OF HUMAN BARRIER-TO-AUTOINTEGRATION FACTOR BAF, NMR, REGULARIZED MEAN STRUCTURE PLUS 20 INDIVIDUAL SIMULATED ANNEALING STRUCTURES

Clore, G.M.

(1999) J Am Chem Soc 121: 2337-2338

Released	1999-06-23
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	PROTEIN (BARRIER-TO-AUTOINTEGRATION FACTOR) (protein)

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1RPY \| pdb_00001rpy	Download File View File

CRYSTAL STRUCTURE OF THE DIMERIC SH2 DOMAIN OF APS

Hu, J., Liu, J., Ghirlando, R., Saltiel, A.R., Hubbard, S.R.

(2003) Mol Cell 12: 1379-1389

Released	2003-12-23
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Rattus norvegicus
Macromolecule	adaptor protein APS (protein)
Unique Ligands	SO4

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1RQQ \| pdb_00001rqq	Download File View File

Crystal Structure of the Insulin Receptor Kinase in Complex with the SH2 Domain of APS

Hu, J., Liu, J., Ghirlando, R., Saltiel, A.R., Hubbard, S.R.

(2003) Mol Cell 12: 1379-1389

Released	2003-12-30
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens Rattus norvegicus
Macromolecule	BISUBSTRATE INHIBITOR (protein) Insulin receptor (protein) adaptor protein APS (protein)
Unique Ligands	112, MN

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1WCR \| pdb_00001wcr	Download File View File

Trimeric Structure of the Enzyme IIA from Escherichia coli Phosphotransferase System Specific for N,N'-Diacetylchitobiose

Tang, C., Clore, G.M.

(2005) J Biological Chem 280: 11770

Released	2005-01-19
Method	SOLUTION NMR
Organisms	Escherichia coli
Macromolecule	PTS SYSTEM, N, N'-DIACETYLCHITOBIOSE-SPECIFIC IIA COMPONENT (protein)

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1X9Z \| pdb_00001x9z	Download File View File

Crystal structure of the MutL C-terminal domain

Guarne, A., Ramon-Maiques, S., Wolff, E.M., Ghirlando, R., Hu, X., Miller, J.H., Yang, W.

(2004) EMBO J 23: 4134-4145

Released	2004-10-26
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Escherichia coli
Macromolecule	DNA mismatch repair protein mutL (protein)
Unique Ligands	CL, GOL, IPA, NA

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1XRX \| pdb_00001xrx	Download File View File

Crystal structure of a DNA-binding protein

Guarne, A., Brendler, T., Zhao, Q., Ghirlando, R., Austin, S., Yang, W.

(2005) EMBO J 24: 1502-1511

Released	2005-05-10
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Escherichia coli
Macromolecule	SeqA protein (protein)
Unique Ligands	CA

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1YM7 \| pdb_00001ym7	Download File View File

G Protein-Coupled Receptor Kinase 2 (GRK2)

Lodowski, D.T., Barnhill, J.F., Pyskadlo, R.M., Ghirlando, R., Sterne-Marr, R., Tesmer, J.J.G.

(2005) Biochemistry 44: 6958-6970

Released	2005-07-05
Method	X-RAY DIFFRACTION 4.5 Å
Organisms	Bos taurus
Macromolecule	Beta-adrenergic receptor kinase 1 (protein)

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2A6M \| pdb_00002a6m	Download File View File

Crystal Structure of the ISHp608 Transposase

Ronning, D.R., Guynet, C., Ton-Hoang, B., Perez, Z.N., Ghirlando, R., Chandler, M., Dyda, F.

(2005) Mol Cell 20: 143-154

Released	2005-10-25
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Helicobacter pylori
Macromolecule	ISHp608 transposase (protein)

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2A6O \| pdb_00002a6o	Download File View File

Crystal Structure of the ISHp608 Transposase in Complex with Stem-loop DNA

Ronning, D.R., Guynet, C., Ton-Hoang, B., Perez, Z.N., Ghirlando, R., Chandler, M., Dyda, F.

(2005) Mol Cell 20: 143-154

Released	2005-10-25
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Helicobacter pylori
Macromolecule	ISHp608 Transposase (protein) 5'-D(CPCPCPCPTPAPGPCPTPTPTPAPGPCPTPAPTPGPGPGPGPA)-3' (nucleic acid)

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2AOQ \| pdb_00002aoq	Download File View File

Crystal structure of MutH-unmethylated DNA complex

Lee, J.Y., Chang, J., Joseph, N., Ghirlando, R., Rao, D.N., Yang, W.

(2005) Mol Cell 20: 155-166

Released	2005-10-11
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Haemophilus influenzae
Macromolecule	DNA mismatch repair protein mutH (protein) 5'-D(GPCPAPTPGPAPTPCPAPTPGPC)-3' (nucleic acid)
Unique Ligands	CA

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2AOR \| pdb_00002aor	Download File View File

Crystal structure of MutH-hemimethylated DNA complex

Lee, J.Y., Chang, J., Joseph, N., Ghirlando, R., Rao, D.N., Yang, W.

(2005) Mol Cell 20: 155-166

Released	2005-10-11
Method	X-RAY DIFFRACTION 2 Å
Organisms	Haemophilus influenzae
Macromolecule	DNA mismatch repair protein mutH (protein) 5'-D(CPAPGPGP(6MA)PTPCPCPAPAPGPCPTPTPGPGPAPTPCPCPTPG)-3' (nucleic acid)
Unique Ligands	CA

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2BW3 \| pdb_00002bw3	Download File View File

Three-dimensional structure of the Hermes DNA transposase

Hickman, A.B., Perez, Z.N., Zhou, L., Musingarimi, P., Ghirlando, R., Hinshaw, J.E., Craig, N.L., Dyda, F.

(2005) Nat Struct Mol Biol 12: 715

Released	2005-07-28
Method	X-RAY DIFFRACTION 2 Å
Organisms	Musca domestica
Macromolecule	TRANSPOSASE (protein)

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2BZF \| pdb_00002bzf	Download File View File

Structural basis for DNA bridging by barrier-to-autointegration factor (BAF)

Bradley, C.M., Ronning, D.R., Ghirlando, R., Craigie, R., Dyda, F.

(2005) Nat Struct Mol Biol 12: 935

Released	2005-09-15
Method	X-RAY DIFFRACTION 2.87 Å
Organisms	Homo sapiens
Macromolecule	BARRIER-TO-AUTOINTEGRATION FACTOR (protein) 5'-D(CPCPTPCPCPAPCP)-3' (nucleic acid) 5'-D(GPTPGPGPAPGPGP)-3' (nucleic acid)

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2EZX \| pdb_00002ezx	Download File View File

SOLUTION STRUCTURE OF HUMAN BARRIER-TO-AUTOINTEGRATION FACTOR BAF, NMR, REGULARIZED MEAN STRUCTURE

Clore, G.M., Cai, M., Gronenborn, A.M.

(1998) Nat Struct Biol 5: 903-909

Released	1999-01-13
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	BARRIER-TO-AUTOINTEGRATION FACTOR (protein)

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2EZY \| pdb_00002ezy	Download File View File

SOLUTION STRUCTURE OF HUMAN BARRIER-TO-AUTOINTEGRATION FACTOR BAF, NMR, ENSEMBLE OF 20 SIMULATED ANNEALING STRUCTURES

Clore, G.M., Cai, M., Gronenborn, A.M.

(1998) Nat Struct Biol 5: 903-909

Released	1999-01-13
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	BARRIER-TO-AUTOINTEGRATION FACTOR (protein)

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2EZZ \| pdb_00002ezz	Download File View File

SOLUTION STRUCTURE OF HUMAN BARRIER-TO-AUTOINTEGRATION FACTOR BAF NMR, ENSEMBLE OF 20 SIMULATED ANNEALING STRUCTURES

Clore, G.M., Cai, M., Gronenborn, A.M.

(1998) Nat Struct Biol 5: 903-909

Released	1999-01-13
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	BARRIER-TO-AUTOINTEGRATION FACTOR (protein)

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2F66 \| pdb_00002f66	Download File View File

Structure of the ESCRT-I endosomal trafficking complex

Kostelansky, M.S., Lee, S., Kim, J., Hurley, J.H.

(2006) Cell 125: 113-126

Released	2006-04-18
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Protein SRN2 (protein) Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease (protein) Vacuolar protein sorting-associated protein VPS28 (protein)
Unique Ligands	SO4

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2F6M \| pdb_00002f6m	Download File View File

Structure of a Vps23-C:Vps28-N subcomplex

Kostelansky, M.S., Lee, S., Kim, J., Hurley, J.H.

(2006) Cell 125: 113-126

Released	2006-04-18
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease (protein) Vacuolar protein sorting-associated protein VPS28 (protein)
Unique Ligands	DDQ, MG