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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Economou, A."

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Search Summary

This query matches 36 Structures.

Refinements

Structure Determination Methodology

experimental (36)

Scientific Name of Source Organism

	Escherichia coli (6)
	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 (6)
	Klebsiella pneumoniae (4)
	Thermus thermophilus (4)
	Escherichia coli str. K-12 substr. MC4100 (3)
	Pseudomonas aeruginosa (3)
	Trypanosoma brucei gambiense (3)
	Discosoma sp. (2)
	Salmonella enterica subsp. enterica serovar Typhi (2)
	Salmonella enterica subsp. enterica serovar Typhimurium (2)

More...

Taxonomy

	Bacteria (30)
	Eukaryota (6)

Experimental Method

	X-RAY DIFFRACTION (24)
	SOLUTION NMR (11)
	ELECTRON MICROSCOPY (1)

Polymer Entity Type

Protein (36)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (6)
	2.0 - 2.5 (15)
	2.5 - 3.0 (2)
	3.0 - 3.5 (1)

Release Date

	2005 - 2009 (5)
	2010 - 2014 (5)
	2015 - 2019 (15)
	2020 - 2024 (11)

Enzyme Classification Name

	Ligases (14)
	Translocases (6)
	Isomerases (3)
	Hydrolases (2)

Symmetry Type

	Cyclic (20)
	Asymmetric (16)

SCOP Classification

	Alpha and beta proteins (a+b) (3)
	All alpha proteins (3)

AllSelected

1 to 25 of 36 Structures

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2FSF \| pdb_00002fsf	Download File View File

Escherichia coli SecA, the preprotein translocase dimeric ATPase

Papanikolau, Y., Petratos, K., Economou, A.

(2007) J Mol Biology 366: 1545-1557

Released	2007-01-16
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli
Macromolecule	Preprotein translocase secA subunit (protein)

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2FSG \| pdb_00002fsg	Download File View File

Complex SecA:ATP from Escherichia coli

Papanikolau, Y., Petratos, K., Economou, A.

(2007) J Mol Biology 366: 1545-1557

Released	2007-01-16
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Escherichia coli
Macromolecule	Preprotein translocase secA subunit (protein)
Unique Ligands	ATP

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2FSH \| pdb_00002fsh	Download File View File

Complex SecA:AMP-PNP from Escherichia coli

Papanikolau, Y., Petratos, K., Economou, A.

(2007) J Mol Biology 366: 1545-1557

Released	2007-01-16
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli
Macromolecule	Preprotein translocase secA subunit (protein)
Unique Ligands	ANP

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2FSI \| pdb_00002fsi	Download File View File

Complex SecA:ADP from Escherichia coli

Papanikolau, Y., Petratos, K., Economou, A.

(2007) J Mol Biology 366: 1545-1557

Released	2007-01-16
Method	X-RAY DIFFRACTION 2.11 Å
Organisms	Escherichia coli
Macromolecule	Preprotein translocase secA subunit (protein)
Unique Ligands	ADP

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2LHK \| pdb_00002lhk	Download File View File

Structural analysis of a chaperone in type III secretion system

Chen, L., Economou, A., Kalodimos, C.G.

(2011) Mol Cell 44: 734-744

Released	2011-12-28
Method	SOLUTION NMR
Organisms	Escherichia coli
Macromolecule	L0052 (protein)

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2M1N \| pdb_00002m1n	Download File View File

Solution structure of a chaperone in type III secretion system

Chen, L., Economou, A., Kalodimos, C.

(2013) Cell Rep 3: 709-715

Released	2013-04-10
Method	SOLUTION NMR
Organisms	Escherichia coli 3003
Macromolecule	Type III secretion system filament chaperone CesA (protein)

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2MLX \| pdb_00002mlx	Download File View File

NMR structure of E. coli Trigger Factor in complex with unfolded PhoA220-310

Saio, T., Guan, X., Rossi, P., Economou, A., Kalodimos, C.G.

(2014) Science 344: 1250494-1250494

Released	2014-05-21
Method	SOLUTION NMR
Organisms	Escherichia coli str. K-12 substr. MC4100
Macromolecule	Alkaline phosphatase (protein) Trigger factor (protein)

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2MLY \| pdb_00002mly	Download File View File

NMR structure of E. coli Trigger Factor in complex with unfolded PhoA1-150

Saio, T., Guan, X., Rossi, P., Economou, A., Kalodimos, C.G.

(2014) Science 344: 1250494-1250494

Released	2014-05-21
Method	SOLUTION NMR
Organisms	Escherichia coli str. K-12 substr. MC4100
Macromolecule	Alkaline phosphatase (protein) Trigger factor (protein)

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2MLZ \| pdb_00002mlz	Download File View File

NMR structure of E. coli Trigger Factor in complex with unfolded PhoA365-471

Saio, T., Guan, X., Rossi, P., Economou, A., Kalodimos, C.G.

(2014) Science 344: 1250494-1250494

Released	2014-05-21
Method	SOLUTION NMR
Organisms	Escherichia coli K-12 Escherichia coli str. K-12 substr. MC4100
Macromolecule	Alkaline phosphatase (protein) Trigger factor (protein)

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2VDA \| pdb_00002vda	Download File View File

Solution structure of the SecA-signal peptide complex

Gelis, I., Bonvin, A.M.J.J., Keramisanou, D., Koukaki, M., Gouridis, G., Karamanou, S., Economou, A., Kalodimos, C.G.

(2007) Cell 131: 756

Released	2007-11-27
Method	SOLUTION NMR
Organisms	Escherichia coli
Macromolecule	MALTOPORIN (protein) TRANSLOCASE SUBUNIT SECA (protein)

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5KP0 \| pdb_00005kp0	Download File View File

Recognition and targeting mechanisms by chaperones in flagella assembly and operation

Khanra, N.K., Rossi, P., Economou, A., Kalodimos, C.G.

(2016) Proc Natl Acad Sci U S A 113: 9798-9803

Released	2016-08-17
Method	SOLUTION NMR
Organisms	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Macromolecule	Flagellar protein FliT,Flagellum-specific ATP synthase (protein)

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5KRW \| pdb_00005krw	Download File View File

Recognition and targeting mechanisms by chaperones in flagella assembly and operation

Khanra, N.K., Rossi, P., Economou, A., Kalodimos, C.G.

(2016) Proc Natl Acad Sci U S A 113: 9798-9803

Released	2016-08-17
Method	SOLUTION NMR
Organisms	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Macromolecule	Flagellar protein FliT,Flagellar hook-associated protein 2 fusion (protein)

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5KS6 \| pdb_00005ks6	Download File View File

Recognition and targeting mechanisms by chaperones in flagella assembly and operation

Khanra, N.K., Rossi, P., Economou, A., Kalodimos, C.G.

(2016) Proc Natl Acad Sci U S A 113: 9798-9803

Released	2016-08-17
Method	SOLUTION NMR
Organisms	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Macromolecule	Flagellar protein FliT (protein)

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6CH1 \| pdb_00006ch1	Download File View File

Crystal structure of the cytoplasmic domain of FlhA in monomeric form

Xing, Q., Shi, K., Kalodimos, C.G.

(2018) Nat Commun 9: 1773-1773

Released	2018-05-16
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Macromolecule	Flagellar biosynthesis protein FlhA (protein)
Unique Ligands	EDO

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6CH2 \| pdb_00006ch2	Download File View File

Crystal structure of the cytoplasmic domain of FlhA and FliT-FliD complex

Xing, Q., Shi, K., Kalodimos, C.G.

(2018) Nat Commun 9: 1773-1773

Released	2018-05-16
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Salmonella enterica subsp. enterica serovar Typhi Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Macromolecule	Flagellar biosynthesis protein FlhA (protein) Flagellar hook-associated protein 2,Flagellar protein FliT (protein)
Unique Ligands	GOL

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6CH3 \| pdb_00006ch3	Download File View File

Crystal structure of the cytoplasmic domain of FlhA and FliS-FliC complex

Xing, Q., Shi, K., Kalodimos, C.G.

(2018) Nat Commun 9: 1773-1773

Released	2018-05-16
Method	X-RAY DIFFRACTION 2.68 Å
Organisms	Salmonella enterica subsp. enterica serovar Typhi Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Macromolecule	Flagellar biosynthesis protein FlhA (protein) Flagellar secretion chaperone FliS,Flagellin (protein)

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6HDZ \| pdb_00006hdz	Download File View File

Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-Sulfamoyl)uridine

Pang, L., De Graef, S., Strelkov, S.V., Weeks, S.D.

(2020) ACS Chem Biol 15: 407-415

Released	2019-12-04
Method	X-RAY DIFFRACTION 2.06 Å
Organisms	Pseudomonas aeruginosa
Macromolecule	Serine--tRNA ligase (protein)
Unique Ligands	EDO, FZK, NA

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6HE1 \| pdb_00006he1	Download File View File

Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine

Pang, L., De Graef, S., Strelkov, S.V., Weeks, S.D.

(2020) ACS Chem Biol 15: 407-415

Released	2019-12-04
Method	X-RAY DIFFRACTION 2.22 Å
Organisms	Pseudomonas aeruginosa
Macromolecule	Serine--tRNA ligase (protein)
Unique Ligands	EDO, FZT, NA

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6HE3 \| pdb_00006he3	Download File View File

Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)cytidine

Pang, L., De Graef, S., Strelkov, S.V., Weeks, S.D.

(2020) ACS Chem Biol 15: 407-415

Released	2019-12-04
Method	X-RAY DIFFRACTION 2.16 Å
Organisms	Pseudomonas aeruginosa
Macromolecule	Serine--tRNA ligase (protein)
Unique Ligands	EDO, FZQ, NA

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6HHV \| pdb_00006hhv	Download File View File

Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)N3-methyluridine

De Graef, S., Pang, L., Strelkov, S.V., Weeks, S.D.

(2020) ACS Chem Biol 15: 407-415

Released	2019-12-18
Method	X-RAY DIFFRACTION 2.18 Å
Organisms	Thermus thermophilus
Macromolecule	Aspartate--tRNA(Asp) ligase (protein)
Unique Ligands	G5Q

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6HHW \| pdb_00006hhw	Download File View File

Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)uridine

De Graef, S., Pang, L., Strelkov, S.V., Weeks, S.D.

(2020) ACS Chem Biol 15: 407-415

Released	2019-12-18
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Thermus thermophilus
Macromolecule	Aspartate--tRNA(Asp) ligase (protein)
Unique Ligands	G5H

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6HHX \| pdb_00006hhx	Download File View File

Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)cytidine

De Graef, S., Pang, L., Strelkov, S.V., Weeks, S.D.

(2020) ACS Chem Biol 15: 407-415

Released	2019-12-18
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Thermus thermophilus
Macromolecule	Aspartate--tRNA(Asp) ligase (protein)
Unique Ligands	G5N

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6HHY \| pdb_00006hhy	Download File View File

Klebsiella pneumoniae Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine

Pang, L., De Graef, S., Weeks, S.D., Strelkov, S.V.

(2020) ACS Chem Biol 15: 407-415

Released	2019-12-18
Method	X-RAY DIFFRACTION 2.27 Å
Organisms	Klebsiella pneumoniae
Macromolecule	Serine--tRNA ligase (protein)
Unique Ligands	CA, EDO, FZT

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6HHZ \| pdb_00006hhz	Download File View File

Klebsiella pneumoniae Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)cytidine

Pang, L., De Graef, S., Weeks, S.D., Strelkov, S.V.

(2020) ACS Chem Biol 15: 407-415

Released	2019-12-18
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Klebsiella pneumoniae
Macromolecule	Serine--tRNA ligase (protein)
Unique Ligands	1PE, CA, CL, EDO, FZQ