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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Cheng, J."

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Search Summary

This query matches 345 Structures.

Refinements

Structure Determination Methodology

experimental (345)

Scientific Name of Source Organism

	Homo sapiens (151)
	Saccharomyces cerevisiae (38)
	Saccharomyces cerevisiae S288C (33)
	synthetic construct (33)
	Thermochaetoides thermophila DSM 1495 (28)
	Mus musculus (23)
	Chelicerata (12)
	Staphylococcus aureus subsp. aureus str. Newman (11)
	Escherichia coli (10)
	Severe acute respiratory syndrome coronavirus 2 (10)

More...

Taxonomy

	Eukaryota (296)
	Bacteria (60)
	other sequences (33)
	Riboviria (25)
	Duplodnaviria (2)
	unclassified bacterial viruses (1)

Experimental Method

	ELECTRON MICROSCOPY (246)
	X-RAY DIFFRACTION (95)
	SOLUTION NMR (4)
	SOLUTION SCATTERING (1)

Polymer Entity Type

	Protein (345)
	RNA (163)
	DNA (12)
	NA-hybrid (2)

Refinement Resolution (Å)

	1.0 - 1.5 (8)
	1.5 - 2.0 (27)
	2.0 - 2.5 (33)
	2.5 - 3.0 (68)
	3.0 - 3.5 (117)
	3.5 - 4.0 (52)
	4.0 - 4.5 (16)
	> 4.5 (20)

Release Date

	2000 - 2004 (7)
	2005 - 2009 (4)
	2010 - 2014 (16)
	2015 - 2019 (72)
	2020 - 2024 (238)
	2025 - 2029 (8)

Enzyme Classification Name

	Hydrolases (154)
	Transferases (87)
	Lyases (50)
	Oxidoreductases (9)
	Isomerases (3)
	Ligases (2)

Membrane Protein Annotation

	mpstruc (47)
	PDBTM (61)
	OPM (34)
	MemProtMD (26)

Symmetry Type

	Asymmetric (310)
	Cyclic (34)
	Dihedral (1)

SCOP Classification

	Alpha and beta proteins (a/b) (7)
	Alpha and beta proteins (a+b) (9)
	All beta proteins (7)
	Membrane and cell surface proteins and peptides (2)
	Artifacts (4)
	All alpha proteins (2)

AllSelected

1 to 25 of 345 Structures

Page 1 of 14

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1F29 \| pdb_00001f29	Download File View File

CRYSTAL STRUCTURE ANALYSIS OF CRUZAIN BOUND TO A VINYL SULFONE DERIVED INHIBITOR (I)

Brinen, L.S., Hansell, E., Roush, W.R., McKerrow, J.H., Fletterick, R.J.

(2000) Structure 8: 831-840

Released	2000-07-26
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Trypanosoma cruzi
Macromolecule	CRUZAIN (protein)
Unique Ligands	VS1

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1F2A \| pdb_00001f2a	Download File View File

CRYSTAL STRUCTURE ANALYSIS OF CRUZAIN BOUND TO A VINYL SULFONE DERIVED INHIBITOR (II)

Brinen, L.S., Hansell, E., Roush, W.R., McKerrow, J.H., Fletterick, R.J.

(2000) Structure 8: 831-840

Released	2000-07-26
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Trypanosoma cruzi
Macromolecule	CRUZAIN (protein)
Unique Ligands	VS2

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1F2B \| pdb_00001f2b	Download File View File

CRYSTAL STRUCTURE ANALYSIS OF CRUZAIN BOUND TO VINYL SULFONE DERIVED INHIBITOR (III)

Brinen, L.S., Hansell, E., Roush, W.R., McKerrow, J.H., Fletterick, R.J.

(2000) Structure 8: 831-840

Released	2000-07-26
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Trypanosoma cruzi
Macromolecule	CRUZAIN (protein)
Unique Ligands	VS3

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1F2C \| pdb_00001f2c	Download File View File

CRYSTAL STRUCTURE ANALYSIS OF CRYZAIN BOUND TO VINYL SULFONE DERIVED INHIBITOR (IV)

Brinen, L.S., Hansell, E., Roush, W.R., McKerrow, J.H., Fletterick, R.J.

(2000) Structure 8: 831-840

Released	2000-07-26
Method	X-RAY DIFFRACTION 2 Å
Organisms	Trypanosoma cruzi
Macromolecule	CRUZAIN (protein)
Unique Ligands	VS4

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1ME3 \| pdb_00001me3	Download File View File

High Resolution Crystal Structure Analysis Of Cruzain non-covalently Bound To A Hydroxymethyl Ketone Inhibitor (II)

Brinen, L.S., Huang, L., Ellman, J.A.

(2003) Bioorg Med Chem 11: 21-29

Released	2002-12-18
Method	X-RAY DIFFRACTION 1.2 Å
Organisms	Trypanosoma cruzi
Macromolecule	Cruzipain (protein)
Unique Ligands	P10

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1ME4 \| pdb_00001me4	Download File View File

High Resolution Crystal Structure Analysis Of Cruzain non-covalently Bound To A Hydroxymethyl Ketone Inhibitor (I)

Brinen, L.S., Huang, L., Ellman, J.A.

(2003) Bioorg Med Chem 11: 21-29

Released	2002-12-18
Method	X-RAY DIFFRACTION 1.2 Å
Organisms	Trypanosoma cruzi
Macromolecule	CRUZIPAIN (protein)
Unique Ligands	T10

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1R6H \| pdb_00001r6h	Download File View File

Solution Structure of human PRL-3

Kozlov, G., Gehring, K., Ekiel, I.

(2004) J Biological Chem 279: 11882-11889

Released	2004-01-13
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	protein tyrosine phosphatase type IVA, member 3 isoform 1 (protein)

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2JIY \| pdb_00002jiy	Download File View File

PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ALA M149 REPLACED WITH TRP (CHAIN M, AM149W)

Fyfe, P.K., Potter, J.A., Cheng, J., Williams, C.M., Watson, A.J., Jones, M.R.

(2007) Biochemistry 46: 10461

Released	2007-09-04
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Cereibacter sphaeroides
Macromolecule	REACTION CENTER PROTEIN H CHAIN (protein) REACTION CENTER PROTEIN L CHAIN (protein) REACTION CENTER PROTEIN M CHAIN (protein)
Unique Ligands	BCL, BPH, CDL, CL, D12, FE, LDA, PO4, SPN, U10

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2JJ0 \| pdb_00002jj0	Download File View File

PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ALA M248 REPLACED WITH TRP (CHAIN M, AM248W)

Fyfe, P.K., Potter, J.A., Cheng, J., Williams, C.M., Watson, A.J., Jones, M.R.

(2007) Biochemistry 46: 10461

Released	2007-09-04
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Cereibacter sphaeroides
Macromolecule	REACTION CENTER PROTEIN H CHAIN (protein) REACTION CENTER PROTEIN L CHAIN (protein) REACTION CENTER PROTEIN M CHAIN (protein)
Unique Ligands	BCL, BPH, CDL, CL, FE, SPN, U10

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2KQX \| pdb_00002kqx	Download File View File

NMR structure of the J-domain (residues 2-72) in the Escherichia coli CbpA

Ekiel, I.

(2010) J Mol Biology 398: 111-121

Released	2010-04-21
Method	SOLUTION NMR
Organisms	Escherichia coli K-12
Macromolecule	Curved DNA-binding protein (protein)

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2PQ4 \| pdb_00002pq4	Download File View File

NMR solution structure of NapD in complex with NapA1-35 signal peptide

Minailiuc, O.M., Ekiel, I., Milad, M., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)

To be published

Released	2008-05-20
Method	SOLUTION NMR
Organisms	Escherichia coli
Macromolecule	Periplasmic nitrate reductase precursor (protein) Protein napD (protein)

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2ZR1 \| pdb_00002zr1	Download File View File

Agglutinin from Abrus Precatorius

Cheng, J., Lu, T.H., Liu, C.L., Lin, J.Y.

(2010) J Biomed Sci 17: 34-34

Released	2009-08-25
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Abrus precatorius
Macromolecule	Agglutinin-1 chain A (protein) Agglutinin-1 chain B (protein)
Unique Ligands	NAG

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3R7W \| pdb_00003r7w	Download File View File

Crystal Structure of Gtr1p-Gtr2p complex

Gong, R., Li, L., Liu, Y., Wang, P., Yang, H., Wang, L., Cheng, J., Guan, K.L., Xu, Y.

(2011) Genes Dev 25: 1668-1673

Released	2011-08-24
Method	X-RAY DIFFRACTION 2.773 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	GTP-binding protein GTR1 (protein) GTP-binding protein GTR2 (protein)
Unique Ligands	GNP, MG

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3V16 \| pdb_00003v16	Download File View File

An intramolecular pi-cation latch in phosphatidylinositol-specific phospholipase C from S.aureus controls substrate access to the active site

Goldstein, R.I., Cheng, J., Stec, B., Roberts, M.F.

(2012) Biochemistry 51: 2579-2587

Released	2012-04-04
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Staphylococcus aureus subsp. aureus str. Newman
Macromolecule	1-phosphatidylinositol phosphodiesterase (protein)
Unique Ligands	CL, INS

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3V18 \| pdb_00003v18	Download File View File

Structure of the Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus

Goldstein, R.I., Cheng, J., Stec, B., Roberts, M.F.

(2012) Biochemistry 51: 2579-2587

Released	2012-04-04
Method	X-RAY DIFFRACTION 2.34 Å
Organisms	Staphylococcus aureus subsp. aureus str. Newman
Macromolecule	1-phosphatidylinositol phosphodiesterase (protein)
Unique Ligands	IPA, SO4

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3V1H \| pdb_00003v1h	Download File View File

Structure of the H258Y mutant of Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus

Goldstein, R.I., Cheng, J., Stec, B., Roberts, M.F.

(2012) Biochemistry 51: 2579-2587

Released	2012-04-04
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Staphylococcus aureus subsp. aureus str. Newman
Macromolecule	1-phosphatidylinositol phosphodiesterase (protein)
Unique Ligands	ACT, INS

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4F2B \| pdb_00004f2b	Download File View File

Modulation of S.Aureus Phosphatidylinositol-Specific Phospholipase C Membrane Binding

Cheng, J., Goldstein, R., Stec, B., Gershenson, A., Roberts, M.F.

(2012) J Biological Chem 287: 40317-40327

Released	2012-12-12
Method	X-RAY DIFFRACTION 2.16 Å
Organisms	Staphylococcus aureus subsp. aureus str. Newman
Macromolecule	1-phosphatidylinositol phosphodiesterase (protein)
Unique Ligands	INS

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4F2T \| pdb_00004f2t	Download File View File

Modulation of S.aureus Phosphatidylinositol-Specific Phospholipase C Membrane Binding.

Cheng, J., Goldstein, R., Stec, B., Gershenson, A., Roberts, M.F.

(2012) J Biological Chem 287: 40317-40327

Released	2012-12-12
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Staphylococcus aureus subsp. aureus str. Newman
Macromolecule	1-phosphatidylinositol phosphodiesterase (protein)
Unique Ligands	ACT

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4F2U \| pdb_00004f2u	Download File View File

Structure of the N254Y/H258Y double mutant of the Phosphatidylinositol-Specific Phospholipase C from S.aureus

Cheng, J., Goldstein, R., Stec, B., Gershenson, A., Roberts, M.F.

(2012) J Biological Chem 287: 40317-40327

Released	2012-12-12
Method	X-RAY DIFFRACTION 2.19 Å
Organisms	Staphylococcus aureus subsp. aureus str. Newman
Macromolecule	1-phosphatidylinositol phosphodiesterase (protein)
Unique Ligands	EPE, SO4

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4GY5 \| pdb_00004gy5	Download File View File

Crystal structure of the tandem tudor domain and plant homeodomain of UHRF1 with Histone H3K9me3

Cheng, J., Yang, Y., Fang, J., Xiao, J., Zhu, T., Chen, F., Wang, P., Xu, Y.

(2013) J Biological Chem 288: 1329-1339

Released	2012-11-14
Method	X-RAY DIFFRACTION 2.956 Å
Organisms	Homo sapiens
Macromolecule	E3 ubiquitin-protein ligase UHRF1 (protein) Peptide from Histone H3.3 (protein)
Unique Ligands	ZN

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4HBK \| pdb_00004hbk	Download File View File

Structure of the Aldose Reductase from Schistosoma japonicum

Liu, J., Cheng, J., Zhang, X., Yang, Z., Hu, W., Xu, Y.

(2013) Parasit Vectors 6: 162-162

Released	2013-06-26
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Schistosoma japonicum
Macromolecule	Aldo-keto reductase family 1, member B4 (Aldose reductase) (protein)

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4I8Y \| pdb_00004i8y	Download File View File

Structure of the unliganded N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from S. aureus

Goldstein, R.I., Cheng, J., Stec, B., Gershenson, A., Roberts, M.F.

(2013) J Biological Chem 288: 14863-14873

Released	2013-04-10
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Staphylococcus aureus subsp. aureus str. Newman
Macromolecule	1-phosphatidylinositol phosphodiesterase (protein)
Unique Ligands	ACT, CL

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4I90 \| pdb_00004i90	Download File View File

Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from S. aureus bound to choline

Goldstein, R.I., Cheng, J., Stec, B., Gershenson, A., Roberts, M.F.

(2013) J Biological Chem 288: 14863-14873

Released	2013-04-10
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Staphylococcus aureus subsp. aureus str. Newman
Macromolecule	1-phosphatidylinositol phosphodiesterase (protein)
Unique Ligands	ACT, CHT, CL

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4I9J \| pdb_00004i9j	Download File View File

Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from S. aureus bound to diC4PC

Goldstein, R.I., Cheng, J., Stec, B., Gershenson, A., Roberts, M.F.

(2013) J Biological Chem 288: 14863-14873

Released	2013-04-10
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Staphylococcus aureus subsp. aureus str. Newman
Macromolecule	1-phosphatidylinositol phosphodiesterase (protein)
Unique Ligands	ACT, XP5

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4I9M \| pdb_00004i9m	Download File View File

Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus bound to HEPES

Goldstein, R.I., Cheng, J., Stec, B., Gershenson, A., Roberts, M.F.

(2013) J Biological Chem 288: 14863-14873

Released	2013-04-10
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Staphylococcus aureus subsp. aureus str. Newman
Macromolecule	1-phosphatidylinositol phosphodiesterase (protein)
Unique Ligands	EPE, SO4

1 to 25 of 345 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1F29 | pdb_00001f29

1F2A | pdb_00001f2a

1F2B | pdb_00001f2b

1F2C | pdb_00001f2c

1ME3 | pdb_00001me3

1ME4 | pdb_00001me4

1R6H | pdb_00001r6h

2JIY | pdb_00002jiy

2JJ0 | pdb_00002jj0

2KQX | pdb_00002kqx

2PQ4 | pdb_00002pq4

2ZR1 | pdb_00002zr1

3R7W | pdb_00003r7w

3V16 | pdb_00003v16

3V18 | pdb_00003v18

3V1H | pdb_00003v1h

4F2B | pdb_00004f2b

4F2T | pdb_00004f2t

4F2U | pdb_00004f2u

4GY5 | pdb_00004gy5

4HBK | pdb_00004hbk

4I8Y | pdb_00004i8y

4I90 | pdb_00004i90

4I9J | pdb_00004i9j

4I9M | pdb_00004i9m