RCSB PDB: Search

1YQB \| pdb_00001yqb	Download File View File

Human Ubiquilin 3

Walker, J.R., Xue, S., Avvakumov, G.V., Newman, E.M., Mackenzie, F., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

To be published

Released	2005-02-08
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	Ubiquilin 3 (protein)

Explore in 3D

1Z6U \| pdb_00001z6u	Download File View File

Np95-like ring finger protein isoform b [Homo sapiens]

Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Mackenzie, F., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

To be published

Released	2005-05-03
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Np95-like ring finger protein isoform b (protein)
Unique Ligands	ZN

Explore in 3D

1ZDN \| pdb_00001zdn	Download File View File

Ubiquitin-conjugating enzyme E2S

Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Mackenzie, F., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

(2012) Mol Cell Proteomics 11: 329-341

Released	2005-05-03
Method	X-RAY DIFFRACTION 1.93 Å
Organisms	Homo sapiens
Macromolecule	Ubiquitin-conjugating enzyme E2S (protein)
Unique Ligands	NA

Explore in 3D

1ZKH \| pdb_00001zkh	Download File View File

Solution structure of a human ubiquitin-like domain in SF3A1

Lukin, J.A., Dhe-Paganon, S., Guido, V., Lemak, A., Avvakumov, G.V., Xue, S., Newman, E.M., Mackenzie, F., Sundstrom, M., Edwards, A., Arrowsmith, C.H., Structural Genomics Consortium (SGC)

To be published

Released	2005-05-10
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Splicing factor 3 subunit 1 (protein)

Explore in 3D

2A4D \| pdb_00002a4d	Download File View File

Structure of the human ubiquitin-conjugating enzyme E2 variant 1 (UEV-1)

Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

(2012) Mol Cell Proteomics 11: 329-341

Released	2005-07-12
Method	X-RAY DIFFRACTION 1.69 Å
Organisms	Homo sapiens
Macromolecule	Ubiquitin-conjugating enzyme E2 variant 1 (protein)

Explore in 3D

2A7L \| pdb_00002a7l	Download File View File

Structure of the human hypothetical ubiquitin-conjugating enzyme, LOC55284

Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

(2012) Mol Cell Proteomics 11: 329-341

Released	2005-09-06
Method	X-RAY DIFFRACTION 1.82 Å
Organisms	Homo sapiens
Macromolecule	Hypothetical ubiquitin-conjugating enzyme LOC55284 (protein)
Unique Ligands	NA

Explore in 3D

2A9U \| pdb_00002a9u	Download File View File

Structure of the N-terminal domain of Human Ubiquitin carboxyl-terminal hydrolase 8 (USP8)

Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, E., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

(2006) J Biological Chem 281: 38061-38070

Released	2005-08-16
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Ubiquitin carboxyl-terminal hydrolase 8 (protein)

Explore in 3D

2AWF \| pdb_00002awf	Download File View File

Structure of human Ubiquitin-conjugating enzyme E2 G1

Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Finerty, P., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

(2012) Mol Cell Proteomics 11: 329-341

Released	2005-09-20
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Ubiquitin-conjugating enzyme E2 G1 (protein)

Explore in 3D

2F4W \| pdb_00002f4w	Download File View File

Human ubiquitin-conjugating enzyme E2 J2

Walker, J.R., Avvakumov, G.V., Xue, S., Finerty Jr., P.J., Newman, E.M., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

(2012) Mol Cell Proteomics 11: 329-341

Released	2005-12-27
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	ubiquitin-conjugating enzyme E2, J2 (protein)

Explore in 3D

2FZP \| pdb_00002fzp	Download File View File

Crystal structure of the USP8 interaction domain of human NRDP1

Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Butler-Cole, C., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

(2006) J Biological Chem 281: 38061-38070

Released	2006-03-28
Method	X-RAY DIFFRACTION 1.87 Å
Organisms	Homo sapiens
Macromolecule	ring finger protein 41 isoform 1 (protein)

Explore in 3D

2GFO \| pdb_00002gfo	Download File View File

Structure of the Catalytic Domain of Human Ubiquitin Carboxyl-terminal Hydrolase 8

Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Finerty Jr., P.J., Butler-Cole, C., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

(2006) J Biological Chem 281: 38061-38070

Released	2006-04-04
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	Ubiquitin carboxyl-terminal hydrolase 8 (protein)
Unique Ligands	ZN

Explore in 3D

2GJW \| pdb_00002gjw	Download File View File

RNA Recognition and Cleavage by an Splicing Endonuclease

Xue, S., Calvin, K., Li, H.

(2006) Science 312: 902-910

Released	2006-09-12
Method	X-RAY DIFFRACTION 2.85 Å
Organisms	Archaeoglobus fulgidus
Macromolecule	tRNA-splicing endonuclease (protein) 5'-R(APGPGPUPCPGPC)-3' (nucleic acid) 5'-R(GPCPGPAPCPCPGPAPCPCPAP(DU)PAPGPCPUPGPCPA)-3' (nucleic acid) 5'-R(UPGPCPAPGPCPGPGPUPCPAP(A23))-3' (nucleic acid)

Explore in 3D

2GWF \| pdb_00002gwf	Download File View File

Structure of a USP8-NRDP1 complex

Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Butler-Cole, C., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

(2006) J Biological Chem 281: 38061-38070

Released	2006-06-06
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	RING finger protein 41 (protein) Ubiquitin carboxyl-terminal hydrolase 8 (protein)

Explore in 3D

2I6T \| pdb_00002i6t	Download File View File

Orthorhombic Structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A

Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Finerty Jr., P.J., Butler-Cole, C., Tempel, W., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S.

To be published

Released	2006-10-24
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	UBIQUITIN-CONJUGATING ENZYME E2-LIKE ISOFORM A (protein)
Unique Ligands	GOL, SO4

Explore in 3D

2IBI \| pdb_00002ibi	Download File View File

Covalent Ubiquitin-USP2 Complex

Walker, J.R., Avvakumov, G.V., Bernstein, G., Xue, S., Finerty Jr., P.J., MacKenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

To be published

Released	2006-10-24
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	Ubiquitin (protein) Ubiquitin carboxyl-terminal hydrolase 2 (protein)
Unique Ligands	NEH, ZN

Explore in 3D

2KVR \| pdb_00002kvr	Download File View File

Solution NMR structure of human ubiquitin specific protease Usp7 UBL domain (residues 537-664). NESG target hr4395c/ SGC-Toronto

Bezsonova, I., Lemak, A., Avvakumov, G., Xue, S., Dhe-Paganon, S., Montelione, G.T., Arrowsmith, C., Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC)

To be published

Released	2010-04-21
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Ubiquitin carboxyl-terminal hydrolase 7 (protein)

Explore in 3D

2L3R \| pdb_00002l3r	Download File View File

NMR structure of UHRF1 Tandem Tudor Domains in a complex with Histone H3 peptide

Nady, N., Lemak, A., Fares, C., Gutmanas, A., Avvakumov, G., Xue, S., Arrowsmith, C., Structural Genomics Consortium (SGC)

(2011) J Biological Chem 286: 24300-24311

Released	2011-04-13
Method	SOLUTION NMR
Organisms	Homo sapiens synthetic construct
Macromolecule	E3 ubiquitin-protein ligase UHRF1 (protein) Histone H3 (protein)

Explore in 3D

2NQ3 \| pdb_00002nq3	Download File View File

Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase

Walker, J.R., Avvakumov, G.V., Xue, S., Butler-Cole, C., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

To be published

Released	2006-11-14
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Itchy homolog E3 ubiquitin protein ligase (protein)
Unique Ligands	CL

Explore in 3D

2NSQ \| pdb_00002nsq	Download File View File

Crystal structure of the C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein

Walker, J.R., Avvakumov, G.V., Xue, S., Butler-Cole, C., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

To be published

Released	2006-12-19
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens
Macromolecule	E3 ubiquitin-protein ligase NEDD4-like protein (protein)
Unique Ligands	EDO, GOL

Explore in 3D

2O25 \| pdb_00002o25	Download File View File

Ubiquitin-Conjugating Enzyme E2-25 kDa Complexed With SUMO-1-Conjugating Enzyme UBC9

Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

To be published

Released	2007-01-16
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	SUMO-1-conjugating enzyme UBC9 (protein) Ubiquitin-conjugating enzyme E2-25 kDa (protein)

Explore in 3D

2OB4 \| pdb_00002ob4	Download File View File

Human Ubiquitin-Conjugating Enzyme CDC34

Neculai, D., Avvakumov, G.V., Xue, S., Walker, J.R., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Sicheri, F., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

(2012) Mol Cell Proteomics 11: 329-341

Released	2006-12-26
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	Ubiquitin-conjugating enzyme E2-32 kDa complementing (protein)

Explore in 3D

2ONI \| pdb_00002oni	Download File View File

Catalytic Domain of the Human NEDD4-like E3 Ligase

Walker, J.R., Avvakumov, G.V., Xue, S., Butler-Cole, C., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

To be published

Released	2007-04-17
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	E3 ubiquitin-protein ligase NEDD4-like protein (protein)
Unique Ligands	NA

Explore in 3D

2QGX \| pdb_00002qgx	Download File View File

Ubiquitin-conjugating enzyme E2Q

Neculai, D., Avvakumov, G.V., Xue, S., Walker, J.R., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Sicheri, F., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

(2012) Mol Cell Proteomics 11: 329-341

Released	2008-03-18
Method	X-RAY DIFFRACTION 2.56 Å
Organisms	Homo sapiens
Macromolecule	Ubiquitin-conjugating enzyme E2 Q1 (protein)

Explore in 3D

2RFK \| pdb_00002rfk	Download File View File

Substrate RNA Positioning in the Archaeal H/ACA Ribonucleoprotein Complex

Liang, B., Xue, S., Terns, R.M., Terns, M.P., Li, H., Southeast Collaboratory for Structural Genomics (SECSG)

(2007) Nat Struct Mol Biol 14: 1189-1195

Released	2008-02-05
Method	X-RAY DIFFRACTION 2.87 Å
Organisms	Pyrococcus furiosus
Macromolecule	Unique protein chains: 3 Unique nucleic acid chains: 3
Unique Ligands	ZN

Explore in 3D

3BI7 \| pdb_00003bi7	Download File View File

Crystal structure of the SRA domain of E3 ubiquitin-protein ligase UHRF1

Walker, J.R., Avvakumov, G.V., Xue, S., Li, Y., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)

(2008) Nature 455: 822-826

Released	2007-12-18
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	E3 ubiquitin-protein ligase UHRF1 (protein)
Unique Ligands	EDO, SO4, UNL

Prepare Data

Validate Data

Deposit Data

Help and Resources

Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1YQB | pdb_00001yqb

1Z6U | pdb_00001z6u

1ZDN | pdb_00001zdn

1ZKH | pdb_00001zkh

2A4D | pdb_00002a4d

2A7L | pdb_00002a7l

2A9U | pdb_00002a9u

2AWF | pdb_00002awf

2F4W | pdb_00002f4w

2FZP | pdb_00002fzp

2GFO | pdb_00002gfo

2GJW | pdb_00002gjw

2GWF | pdb_00002gwf

2I6T | pdb_00002i6t

2IBI | pdb_00002ibi

2KVR | pdb_00002kvr

2L3R | pdb_00002l3r

2NQ3 | pdb_00002nq3

2NSQ | pdb_00002nsq

2O25 | pdb_00002o25

2OB4 | pdb_00002ob4

2ONI | pdb_00002oni

2QGX | pdb_00002qgx

2RFK | pdb_00002rfk

3BI7 | pdb_00003bi7