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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Tong, L."

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Search Summary

This query matches 933 Structures.

Refinements

Structure Determination Methodology

experimental (933)

Scientific Name of Source Organism

	Homo sapiens (186)
	synthetic construct (47)
	Bacillus subtilis (41)
	Mus musculus (35)
	Saccharomyces cerevisiae (28)
	Escherichia coli (18)
	Escherichia coli K-12 (15)
	Lactococcus lactis (13)
	Pseudomonas aeruginosa (13)
	Bacillus cereus ATCC 14579 (11)

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Taxonomy

	Bacteria (521)
	Eukaryota (289)
	Archaea (54)
	other sequences (47)
	Duplodnaviria (17)
	Riboviria (7)
	Monodnaviria (2)
	Eukaryota (eukaryotes) (1)

Experimental Method

	X-RAY DIFFRACTION (908)
	ELECTRON MICROSCOPY (24)
	SOLUTION NMR (1)

Polymer Entity Type

	Protein (933)
	RNA (15)

Refinement Resolution (Å)

	1.0 - 1.5 (18)
	1.5 - 2.0 (211)
	2.0 - 2.5 (365)
	2.5 - 3.0 (260)
	3.0 - 3.5 (72)
	3.5 - 4.0 (6)

Release Date

	1990 - 1994 (3)
	1995 - 1999 (20)
	2000 - 2004 (109)
	2005 - 2009 (404)
	2010 - 2014 (260)
	2015 - 2019 (95)
	2020 - 2024 (42)

Enzyme Classification Name

	Hydrolases (166)
	Transferases (127)
	Ligases (63)
	Oxidoreductases (53)
	Lyases (27)
	Isomerases (15)
	Translocases (1)

Membrane Protein Annotation

	OPM (3)
	mpstruc (3)

Symmetry Type

	Asymmetric (485)
	Cyclic (410)
	Dihedral (140)
	Helical (2)
	Octahedral (2)

SCOP Classification

	Alpha and beta proteins (a/b) (174)
	Artifacts (145)
	Alpha and beta proteins (a+b) (115)
	All beta proteins (91)
	All alpha proteins (60)
	Coiled coil proteins (2)
	Multi-domain proteins (alpha and beta) (6)
	Small proteins (2)
	Peptides (1)

AllSelected

1 to 25 of 933 Structures

Page 1 of 38

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1AFV \| pdb_00001afv	Download File View File

HIV-1 CAPSID PROTEIN (P24) COMPLEX WITH FAB25.3

Momany, C., Kovari, L.C., Prongay, A.J., Keller, W., Gitti, R.K., Lee, B.M., Gorbalenya, A.E., Tong, L., Mcclure, J., Ehrlich, L.S., Summers, M.F., Carter, C., Rossmann, M.G.

(1996) Nat Struct Biol 3: 763-770

Released	1997-08-20
Method	X-RAY DIFFRACTION 3.7 Å
Organisms	Human immunodeficiency virus 1 Mus musculus
Macromolecule	ANTIBODY FAB25.3 FRAGMENT (HEAVY CHAIN) (protein) ANTIBODY FAB25.3 FRAGMENT (LIGHT CHAIN) (protein) HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 CAPSID PROTEIN (protein)
Unique Ligands	PB

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1BHF \| pdb_00001bhf	Download File View File

P56LCK SH2 DOMAIN INHIBITOR COMPLEX

Tong, L., Warren, T.C., Lukas, S., Schembri-King, J., Betageri, R., Proudfoot, J.R., Jakes, S.

(1998) J Biological Chem 273: 20238-20242

Released	1998-10-21
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	INHIBITOR ACE-IPA-GLU-GLU-ILE (protein) T-LYMPHOCYTE-SPECIFIC PROTEIN TYROSINE KINASE P56LCK (protein)

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1BHH \| pdb_00001bhh	Download File View File

FREE P56LCK SH2 DOMAIN

Tong, L., Warren, T.C., Lukas, S., Schembri-King, J., Betageri, R., Proudfoot, J.R., Jakes, S.

(1998) J Biological Chem 273: 20238-20242

Released	1998-10-21
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	P56 LCK TYROSINE KINASE SH2 DOMAIN (protein) T-LYMPHOCYTE-SPECIFIC PROTEIN TYROSINE KINASE P56LCK (protein)

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1BI7 \| pdb_00001bi7	Download File View File

MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURE OF THE CDK6-P16INK4A TUMOR SUPPRESSOR COMPLEX

Russo, A.A., Tong, L., Lee, J.O., Jeffrey, P.D., Pavletich, N.P.

(1998) Nature 395: 237-243

Released	1999-01-13
Method	X-RAY DIFFRACTION 3.4 Å
Organisms	Homo sapiens
Macromolecule	CYCLIN-DEPENDENT KINASE 6 (protein) MULTIPLE TUMOR SUPPRESSOR (protein)

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1BI8 \| pdb_00001bi8	Download File View File

MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEX

Russo, A.A., Tong, L., Lee, J.O., Jeffrey, P.D., Pavletich, N.P.

(1998) Nature 395: 237-243

Released	1999-01-13
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	CYCLIN-DEPENDENT KINASE 6 (protein) CYCLIN-DEPENDENT KINASE INHIBITOR (protein)

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1BIL \| pdb_00001bil	Download File View File

CRYSTALLOGRAPHIC STUDIES ON THE BINDING MODES OF P2-P3 BUTANEDIAMIDE RENIN INHIBITORS

Tong, L.

(1995) J Biological Chem 270: 29520-29524

Released	1996-01-29
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	Renin (protein)
Unique Ligands	0IU

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1BIM \| pdb_00001bim	Download File View File

CRYSTALLOGRAPHIC STUDIES ON THE BINDING MODES OF P2-P3 BUTANEDIAMIDE RENIN INHIBITORS

Tong, L.

(1995) J Biological Chem 270: 29520-29524

Released	1996-01-29
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	Renin (protein)
Unique Ligands	0QB

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1CA4 \| pdb_00001ca4	Download File View File

STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 (TRAF2)

Park, Y.C., Burkitt, V., Villa, A.R., Tong, L., Wu, H.

(1999) Nature 398: 533-538

Released	1999-04-12
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	PROTEIN (TNF RECEPTOR ASSOCIATED FACTOR 2) (protein)

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1CA9 \| pdb_00001ca9	Download File View File

STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A PEPTIDE FROM TNF-R2

Park, Y.C., Burkitt, V., Villa, A.R., Tong, L., Wu, H.

(1999) Nature 398: 533-538

Released	1999-04-12
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	PROTEIN (TNF RECEPTOR ASSOCIATED FACTOR 2) (protein) PROTEIN (TNF-R2) (protein)

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1DO8 \| pdb_00001do8	Download File View File

CRYSTAL STRUCTURE OF A CLOSED FORM OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME

Yang, Z., Floyd, D.L., Loeber, G., Tong, L.

(2000) Nat Struct Biol 7: 251-257

Released	2000-03-06
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	MALIC ENZYME (protein)
Unique Ligands	MN, NAD, OXL

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1EFK \| pdb_00001efk	Download File View File

STRUCTURE OF HUMAN MALIC ENZYME IN COMPLEX WITH KETOMALONATE

Yang, Z., Floyd, D.L., Loeber, G., Tong, L.

(2000) Nat Struct Biol 7: 251-257

Released	2000-03-08
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	MALIC ENZYME (protein)
Unique Ligands	MAK, MG, NAD

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1EFL \| pdb_00001efl	Download File View File

HUMAN MALIC ENZYME IN A QUATERNARY COMPLEX WITH NAD, MG, AND TARTRONATE

Yang, Z., Floyd, D.L., Loeber, G., Tong, L.

(2000) Nat Struct Biol 7: 251-257

Released	2000-03-08
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	MALIC ENZYME (protein)
Unique Ligands	MG, NAD, TTN

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1FYV \| pdb_00001fyv	Download File View File

CRYSTAL STRUCTURE OF THE TIR DOMAIN OF HUMAN TLR1

Xu, Y., Tao, X., Shen, B., Horng, T., Medzhitov, R., Manley, J.L., Tong, L.

(2000) Nature 408: 111-115

Released	2000-11-22
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	TOLL-LIKE RECEPTOR 1 (protein)

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1FYW \| pdb_00001fyw	Download File View File

CRYSTAL STRUCTURE OF THE TIR DOMAIN OF HUMAN TLR2

Xu, Y., Tao, X., Shen, B., Horng, T., Medzhitov, R., Manley, J.L., Tong, L., Northeast Structural Genomics Consortium (NESG)

(2000) Nature 408: 111-115

Released	2000-11-22
Method	X-RAY DIFFRACTION 3 Å
Organisms	Homo sapiens
Macromolecule	TOLL-LIKE RECEPTOR 2 (protein)

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1FYX \| pdb_00001fyx	Download File View File

CRYSTAL STRUCTURE OF P681H MUTANT OF TIR DOMAIN OF HUMAN TLR2

Xu, Y., Tao, X., Shen, B., Horng, T., Medzhitov, R., Manley, J.L., Tong, L.

(2000) Nature 408: 111-115

Released	2000-11-22
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	TOLL-LIKE RECEPTOR 2 (protein)

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1G3N \| pdb_00001g3n	Download File View File

STRUCTURE OF A P18(INK4C)-CDK6-K-CYCLIN TERNARY COMPLEX

Jeffrey, P.D., Tong, L., Pavletich, N.P.

(2000) Genes Dev 14: 3115-3125

Released	2001-01-10
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens Human gammaherpesvirus 8
Macromolecule	CYCLIN-DEPENDENT KINASE 6 (protein) CYCLIN-DEPENDENT KINASE 6 INHIBITOR (protein) V-CYCLIN (protein)

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1GIC \| pdb_00001gic	Download File View File

CONCANAVALIN A COMPLEXED WITH METHYL ALPHA-D-GLUCOPYRANOSIDE

Bradbrook, G.M., Gleichmann, T., Harrop, S.J., Helliwell, J.R., Habash, J., Kalb(Gilboa), A.J., Tong, L., Wan, T.C.M., Yariv, J.

(1996) Acta Crystallogr D Biol Crystallogr 52: 143-155

Released	1997-08-20
Method	X-RAY DIFFRACTION 2 Å
Organisms	Canavalia ensiformis
Macromolecule	CONCANAVALIN A (protein)
Unique Ligands	CA, GYP, MN

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1GTD \| pdb_00001gtd	Download File View File

NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG ID TT50) STRUCTURE OF MTH169, THE PURS SUBUNIT OF FGAM SYNTHETASE

Batra, R., Christendat, D., Saxild, H.H., Arrowsmith, C., Tong, L.

(2002) Proteins 49: 285

Released	2002-12-12
Method	X-RAY DIFFRACTION 2.56 Å
Organisms	Methanothermobacter thermautotrophicus
Macromolecule	MTH169 (protein)

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1GZ3 \| pdb_00001gz3	Download File View File

Molecular mechanism for the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate

Yang, Z., Lanks, C.W., Tong, L.

(2002) Structure 10: 951-960

Released	2003-05-22
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	NAD-dependent malic enzyme, mitochondrial (protein)
Unique Ligands	ATP, FUM, MN, OXL

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1GZ4 \| pdb_00001gz4	Download File View File

molecular mechanism of the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate

Yang, Z., Lanks, C.W., Tong, L.

(2002) Structure 10: 951

Released	2002-07-25
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	NAD-DEPENDENT MALIC ENZYME (protein)
Unique Ligands	ATP, FUM, MN, TTN

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1H2H \| pdb_00001h2h	Download File View File

Crystal structure of TM1643

Yang, Z., Savchenko, A., Edwards, A., Arrowsmith, C., Tong, L., Northeast Structural Genomics Consortium (NESG)

(2003) J Biological Chem 278: 8804-8808

Released	2002-08-15
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Thermotoga maritima
Macromolecule	HYPOTHETICAL PROTEIN TM1643 (protein)
Unique Ligands	NAD

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1HRN \| pdb_00001hrn	Download File View File

HIGH RESOLUTION CRYSTAL STRUCTURES OF RECOMBINANT HUMAN RENIN IN COMPLEX WITH POLYHYDROXYMONOAMIDE INHIBITORS

Tong, L., Anderson, P.C.

(1995) J Mol Biology 250: 211-222

Released	1995-06-03
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	RENIN (protein)
Unique Ligands	03D, NAG

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1I45 \| pdb_00001i45	Download File View File

YEAST TRIOSEPHOSPHATE ISOMERASE (MUTANT)

Rozovsky, S., Jogl, G., Tong, L., McDermott, A.E.

(2001) J Mol Biology 310: 271-280

Released	2001-06-30
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	TRIOSEPHOSPHATE ISOMERASE (protein)

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1IAN \| pdb_00001ian	Download File View File

HUMAN P38 MAP KINASE INHIBITOR COMPLEX

Tong, L.

(1997) Nat Struct Biol 4: 311-316

Released	1998-05-06
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	P38 MAP KINASE (protein)
Unique Ligands	D13

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1ID4 \| pdb_00001id4	Download File View File

CRYSTAL STRUCTURE OF THE CATALYTIC SITE MUTANT (H157Q) OF THE HUMAN CYTOMEGALOVIRUS PROTEASE

Khayat, R., Batra, R., Massariol, M.J., Lagace, L., Tong, L.

(2001) Biochemistry 40: 6344-6351

Released	2001-06-06
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Human herpesvirus 5 strain AD169
Macromolecule	CAPSID PROTEIN P40: ASSEMBLIN PROTEASE (protein)

1 to 25 of 933 Structures

Page 1 of 38

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1AFV | pdb_00001afv

1BHF | pdb_00001bhf

1BHH | pdb_00001bhh

1BI7 | pdb_00001bi7

1BI8 | pdb_00001bi8

1BIL | pdb_00001bil

1BIM | pdb_00001bim

1CA4 | pdb_00001ca4

1CA9 | pdb_00001ca9

1DO8 | pdb_00001do8

1EFK | pdb_00001efk

1EFL | pdb_00001efl

1FYV | pdb_00001fyv

1FYW | pdb_00001fyw

1FYX | pdb_00001fyx

1G3N | pdb_00001g3n

1GIC | pdb_00001gic

1GTD | pdb_00001gtd

1GZ3 | pdb_00001gz3

1GZ4 | pdb_00001gz4

1H2H | pdb_00001h2h

1HRN | pdb_00001hrn

1I45 | pdb_00001i45

1IAN | pdb_00001ian

1ID4 | pdb_00001id4