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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Pluckthun, A."

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Search Summary

This query matches 75 Structures.

Refinements

Structure Determination Methodology

experimental (75)

Scientific Name of Source Organism

	synthetic construct (43)
	Homo sapiens (16)
	Mus musculus (13)
	Rattus norvegicus (6)
	Bifidobacterium longum (4)
	Pyrococcus abyssi GE5 (4)
	Clavularia sp. (2)
	Lambdavirus lambda (2)
	Staphylococcus phage 2638A (2)
	Xenopus laevis (2)

More...

Taxonomy

	other sequences (43)
	Eukaryota (32)
	Bacteria (8)
	Duplodnaviria (6)
	Archaea (4)
	Monodnaviria (1)
	Riboviria (1)

Experimental Method

	X-RAY DIFFRACTION (67)
	ELECTRON MICROSCOPY (7)
	SOLUTION NMR (1)

Polymer Entity Type

Protein (75)

Refinement Resolution (Å)

	1.0 - 1.5 (5)
	1.5 - 2.0 (18)
	2.0 - 2.5 (30)
	2.5 - 3.0 (11)
	3.0 - 3.5 (5)
	4.0 - 4.5 (3)
	> 4.5 (2)

Release Date

	1995 - 1999 (2)
	2000 - 2004 (11)
	2005 - 2009 (7)
	2010 - 2014 (11)
	2015 - 2019 (24)
	2020 - 2024 (20)

Enzyme Classification Name

	Hydrolases (10)
	Transferases (6)

Membrane Protein Annotation

	PDBTM (11)
	OPM (10)
	mpstruc (10)
	MemProtMD (9)

Symmetry Type

	Asymmetric (68)
	Cyclic (7)

SCOP Classification

	All beta proteins (14)
	Alpha and beta proteins (a+b) (7)
	Artifacts (4)

AllSelected

1 to 25 of 75 Structures

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1C12 \| pdb_00001c12	Download File View File

INSIGHT IN ODORANT PERCEPTION: THE CRYSTAL STRUCTURE AND BINDING CHARACTERISTICS OF ANTIBODY FRAGMENTS DIRECTED AGAINST THE MUSK ODORANT TRASEOLIDE

Langedijk, A.C., Spinelli, S., Anguille, C., Hermans, P., Nederlof, J., Butenandt, J., Honegger, A., Cambillau, C., Pluckthun, A.

(1999) J Mol Biology 292: 855-869

Released	1999-08-14
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Mus musculus
Macromolecule	PROTEIN (ANTIBODY FRAGMENT FAB) (protein)
Unique Ligands	TRZ

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1C5E \| pdb_00001c5e	Download File View File

BACTERIOPHAGE LAMBDA HEAD PROTEIN D

Yang, F., Forrer, P., Dauter, Z., Pluckthun, A., Wlodawer, A.

(2000) Nat Struct Biol 7: 230-237

Released	2000-03-08
Method	X-RAY DIFFRACTION 1.1 Å
Organisms	Lambdavirus lambda
Macromolecule	HEAD DECORATION PROTEIN (protein)
Unique Ligands	GOL

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1G3P \| pdb_00001g3p	Download File View File

CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAINS OF BACTERIOPHAGE MINOR COAT PROTEIN G3P

Lubkowski, J., Hennecke, F., Pluckthun, A., Wlodawer, A.

(1998) Nat Struct Biol 5: 140-147

Released	1998-01-28
Method	X-RAY DIFFRACTION 1.46 Å
Organisms	Inovirus M13
Macromolecule	MINOR COAT PROTEIN (protein)
Unique Ligands	SO4

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1H8N \| pdb_00001h8n	Download File View File

Three-dimensional structure of anti-ampicillin single chain Fv fragment from phage-displayed murine antibody libraries

Jung, S., Spinelli, S., Schimmele, B., Honegger, A., Pugliese, L., Cambillau, C., Pluckthun, A.

(2001) J Mol Biology 309: 701

Released	2001-08-02
Method	X-RAY DIFFRACTION 1.87 Å
Organisms	Mus musculus
Macromolecule	MUTANT AL2 6E7S9G (protein)
Unique Ligands	GOL, SO4

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1H8O \| pdb_00001h8o	Download File View File

Three-dimensional structure of anti-ampicillin single chain Fv fragment.

Burmester, J., Spinelli, S., Pugliese, L., Krebber, A., Honegger, A., Jung, S., Schimmele, B., Cambillau, C., Pluckthun, A.

(2001) J Mol Biology 309: 671

Released	2001-08-02
Method	X-RAY DIFFRACTION 2.75 Å
Organisms	Mus musculus
Macromolecule	MUTANT AL2 6E7P9G (protein)
Unique Ligands	SO4

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1H8S \| pdb_00001h8s	Download File View File

Three-dimensional structure of anti-ampicillin single chain Fv fragment complexed with the hapten.

Burmester, J., Spinelli, S., Pugliese, L., Krebber, A., Honegger, A., Jung, S., Schimmele, B., Cambillau, C., Pluckthun, A.

(2001) J Mol Biology 309: 671

Released	2001-08-02
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Mus musculus
Macromolecule	MUTANT AL2 6E7P9G (protein)
Unique Ligands	AIC, SO4

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1I3G \| pdb_00001i3g	Download File View File

CRYSTAL STRUCTURE OF AN AMPICILLIN SINGLE CHAIN FV, FORM 1, FREE

Jung, S., Spinelli, S., Schimmele, B., Honegger, A., Pugliese, L., Cambillau, C., Pluckthun, A.

(2001) J Mol Biology 309: 671-685

Released	2001-10-17
Method	X-RAY DIFFRACTION 2.44 Å
Organisms	Mus musculus
Macromolecule	ANTIBODY FV FRAGMENT (protein)
Unique Ligands	MPD

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1IHR \| pdb_00001ihr	Download File View File

Crystal structure of the dimeric C-terminal domain of TonB

Chang, C., Mooser, A., Pluckthun, A., Wlodawer, A.

(2001) J Biological Chem 276: 27535-27540

Released	2001-08-01
Method	X-RAY DIFFRACTION 1.55 Å
Organisms	Escherichia coli
Macromolecule	TonB protein (protein)
Unique Ligands	BR

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1JPF \| pdb_00001jpf	Download File View File

Crystal Structure Of The LCMV Peptidic Epitope Gp276 In Complex With The Murine Class I Mhc Molecule H-2Db

Ciatto, C., Tissot, A.C., Tschopp, M., Capitani, G., Pecorari, F., Pluckthun, A., Grutter, M.G.

(2001) J Mol Biology 312: 1059-1071

Released	2001-10-24
Method	X-RAY DIFFRACTION 2.18 Å
Organisms	Mus musculus
Macromolecule	BETA-2-MICROGLOBULIN (protein) H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN (protein) LCMV peptidic epitope gp276 (protein)

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1JPG \| pdb_00001jpg	Download File View File

Crystal Structure Of The LCMV Peptidic Epitope Np396 In Complex With The Murine Class I Mhc Molecule H-2Db

Ciatto, C., Tissot, A.C., Tschopp, M., Capitani, G., Pecorari, F., Pluckthun, A., Grutter, M.G.

(2001) J Mol Biology 312: 1059-1071

Released	2001-10-24
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Mus musculus
Macromolecule	BETA-2-MICROGLOBULIN (protein) H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN (protein) LCMV peptidic epitope np396 (protein)

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1N3N \| pdb_00001n3n	Download File View File

Crystal structure of a mycobacterial hsp60 epitope with the murine class I MHC molecule H-2Db

Ciatto, C., Capitani, G., Tissot, A.C., Pecorari, F., Pluckthun, A., Grutter, M.G.

(2003) FEBS Lett 543: 11-15

Released	2003-05-27
Method	X-RAY DIFFRACTION 3 Å
Organisms	Mus musculus
Macromolecule	BETA-2-MICROGLOBULIN (protein) H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN (protein) mycobacterial hsp60 decameric epitope (protein)
Unique Ligands	SO4

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1P4B \| pdb_00001p4b	Download File View File

Three-Dimensional Structure Of a Single Chain Fv Fragment Complexed With The peptide GCN4(7P-14P).

Zahnd, C., Spinelli, S., Luginbuhl, B., Jermutus, L., Amstutz, P., Cambillau, C., Pluckthun, A.

(2004) J Biological Chem 279: 18870-18877

Released	2004-05-04
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Mus musculus
Macromolecule	Antibody Variable heavy chain (protein) Antibody Variable light chain (protein) GCN4(7P-14P) peptide (protein)

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1P4I \| pdb_00001p4i	Download File View File

Crystal Structure of scFv against peptide GCN4

Zahnd, C., Spinelli, S., Luginbuhl, B., Jermutus, L., Amstutz, P., Cambillau, C., Pluckthun, A.

(2004) J Biological Chem 279: 18870-18877

Released	2004-05-04
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Mus musculus
Macromolecule	ANTIBODY VARIABLE LIGHT CHAIN (protein) antibody variable heavy chain (protein)

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1VD0 \| pdb_00001vd0	Download File View File

Capsid stabilizing protein GPD, NMR, 20 Structures

Iwai, H., Forrer, P., Pluckthun, A., Guntert, P., RIKEN Structural Genomics/Proteomics Initiative (RSGI)

(2005) J Biomol NMR 31: 351-356

Released	2005-03-29
Method	SOLUTION NMR
Organisms	Lambdavirus lambda
Macromolecule	Head decoration protein (protein)

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2A9M \| pdb_00002a9m	Download File View File

Structural Analysis of a Tight-binding Fluorescein-scFv; apo form

Cambillau, C., Spinelli, S., Honegger, A., Pluckthun, A.

(2005) Protein Sci 14: 2537-2549

Released	2005-10-25
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	fluorescein-scfv (protein)

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2A9N \| pdb_00002a9n	Download File View File

A Mutation Designed to Alter Crystal Packing Permits Structural Analysis of a Tight-binding Fluorescein-scFv complex

Cambillau, C., Spinelli, S., Honegger, A., Pluckthun, A.

(2005) Protein Sci 14: 2537-2549

Released	2005-10-25
Method	X-RAY DIFFRACTION 3 Å
Organisms	Homo sapiens
Macromolecule	fluorescein-scfv (protein)
Unique Ligands	ORE

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2BKG \| pdb_00002bkg	Download File View File

Crystal structure of E3_19 a designed ankyrin repeat protein

Binz, H.K., Kohl, A., Pluckthun, A., Grutter, M.G.

(2006) Proteins 65: 280

Released	2006-06-21
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	synthetic construct
Macromolecule	SYNTHETIC CONSTRUCT ANKYRIN REPEAT PROTEIN E3_19 (protein)

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2BKK \| pdb_00002bkk	Download File View File

Crystal structure of Aminoglycoside Phosphotransferase APH(3')-IIIa in complex with the inhibitor AR_3a

Kohl, A., Amstutz, P., Parizek, P., Binz, H.K., Briand, C., Capitani, G., Forrer, P., Pluckthun, A., Grutter, M.G.

(2005) Structure 13: 1131

Released	2005-08-09
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Enterococcus faecalis synthetic construct
Macromolecule	AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE (protein) DESIGNED ANKYRIN REPEAT INHIBITOR AR_3A (protein)
Unique Ligands	ADP, MG

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2JAB \| pdb_00002jab	Download File View File

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

Zahnd, C., Wyler, E., Schwenk, J.M., Steiner, D., Lawrence, M.C., McKern, N.M., Pecorari, F., Ward, C.W., Joos, T.O., Pluckthun, A.

(2007) J Mol Biology 369: 1015

Released	2007-05-08
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	synthetic construct
Macromolecule	H10-2-G3 (protein)

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2XEE \| pdb_00002xee	Download File View File

Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module.

Kramer, M., Wetzel, S.K., Pluckthun, A., Mittl, P., Grutter, M.

(2010) J Mol Biology 404: 381

Released	2010-08-18
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	synthetic construct
Macromolecule	NI3C DARPIN MUTANT5 (protein)

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2XEH \| pdb_00002xeh	Download File View File

Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module.

Kramer, M., Wetzel, S.K., Pluckthun, A., Mittl, P., Grutter, M.

(2010) J Mol Biology 404: 381

Released	2010-08-18
Method	X-RAY DIFFRACTION 1.81 Å
Organisms	synthetic construct
Macromolecule	NI3C MUT6 (protein)
Unique Ligands	SO4

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2XEN \| pdb_00002xen	Download File View File

Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module.

Kramer, M., Wetzel, S.K., Pluckthun, A., Mittl, P., Grutter, M.

(2010) J Mol Biology 404: 381

Released	2010-08-18
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	synthetic construct
Macromolecule	NI1C MUT4 (protein)
Unique Ligands	EDO, MOH, SO4

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3HG0 \| pdb_00003hg0	Download File View File

Crystal structure of a DARPin in complex with ORF49 from Lactococcal phage TP901-1

Veesler, D., Dreier, B., Blangy, S., Lichiere, J., Tremblay, D., Moineau, S., Spinelli, S., Tegoni, M., Pluckthun, A., Campanacci, V., Cambillau, C.

(2009) J Biological Chem 284: 30718-30726

Released	2009-09-08
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Lactococcus phage TP901-1 synthetic construct
Macromolecule	Baseplate protein (protein) Designed Ankyrin Repeat Protein (DARPin) 20 (protein)

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3ZU7 \| pdb_00003zu7	Download File View File

Crystal structure of a designed selected Ankyrin Repeat protein in complex with the MAP kinase ERK2

Kummer, L., Mittl, P.R., Pluckthun, A.

(2012) Proc Natl Acad Sci U S A 109: E2248

Released	2012-06-27
Method	X-RAY DIFFRACTION 1.97 Å
Organisms	Rattus norvegicus synthetic construct
Macromolecule	DESIGNED ANKYRIN REPEAT PROTEIN (protein) MITOGEN-ACTIVATED PROTEIN KINASE 1 (protein)

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3ZUV \| pdb_00003zuv	Download File View File

Crystal structure of a designed selected Ankyrin Repeat protein in complex with the phosphorylated MAP kinase ERK2

Kummer, L., Mittl, P.R., Pluckthun, A.

(2012) Proc Natl Acad Sci U S A 109: E2248

Released	2012-06-27
Method	X-RAY DIFFRACTION 2.72 Å
Organisms	Rattus norvegicus synthetic construct
Macromolecule	DESIGNED ANKYRIN REPEAT PROTEIN (protein) MITOGEN-ACTIVATED PROTEIN KINASE 1 (protein)
Unique Ligands	SO4

1 to 25 of 75 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1C12 | pdb_00001c12

1C5E | pdb_00001c5e

1G3P | pdb_00001g3p

1H8N | pdb_00001h8n

1H8O | pdb_00001h8o

1H8S | pdb_00001h8s

1I3G | pdb_00001i3g

1IHR | pdb_00001ihr

1JPF | pdb_00001jpf

1JPG | pdb_00001jpg

1N3N | pdb_00001n3n

1P4B | pdb_00001p4b

1P4I | pdb_00001p4i

1VD0 | pdb_00001vd0

2A9M | pdb_00002a9m

2A9N | pdb_00002a9n

2BKG | pdb_00002bkg

2BKK | pdb_00002bkk

2JAB | pdb_00002jab

2XEE | pdb_00002xee

2XEH | pdb_00002xeh

2XEN | pdb_00002xen

3HG0 | pdb_00003hg0

3ZU7 | pdb_00003zu7

3ZUV | pdb_00003zuv