RCSB PDB: Search

3JCX \| pdb_00003jcx	Download File View File

Canine Parvovirus complexed with Fab E

Organtini, L.J., Iketani, S., Huang, K., Ashley, R.E., Makhov, A.M., Conway, J.F., Parrish, C.R., Hafenstein, S.

(2016) J Virol 90: 9733-9742

Released	2016-07-20
Method	ELECTRON MICROSCOPY 4.1 Å
Organisms	Canine parvovirus Rattus norvegicus
Macromolecule	Capsid protein 2 (protein) Fab E heavy chain (protein) Fab E light chain (protein)

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6I3H \| pdb_00006i3h	Download File View File

Crystal structure of influenza A virus M1 N-terminal domain (G18A mutation)

Miyake, Y., Keusch, J.J., Decamps, L., Ho-Xuan, H., Iketani, S., Gut, H., Kutay, U., Helenius, A., Yamauchi, Y.

(2019) Nat Microbiol 4: 578-586

Released	2019-09-18
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Influenza A virus
Macromolecule	Matrix protein 1 (protein)
Unique Ligands	PO4

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7JST \| pdb_00007jst	Download File View File

Crystal structure of SARS-CoV-2 3CL in apo form

Iketani, S., Forouhar, F., Liu, H., Hong, S.J., Lin, F.-Y., Nair, M.S., Zask, A., Huang, Y., Xing, L., Stockwell, B.R., Chavez, A., Ho, D.D.

(2021) Nat Commun 12: 2016-2016

Released	2021-03-03
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	PO4

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7JSU \| pdb_00007jsu	Download File View File

Crystal structure of SARS-CoV-2 3CL protease in complex with GC376

Iketani, S., Forouhar, F., Liu, H., Hong, S.J., Lin, F.-Y., Nair, M.S., Zask, A., Xing, L., Stockwell, B.R., Chavez, A., Ho, D.D.

(2021) Nat Commun 12: 2016-2016

Released	2021-03-10
Method	X-RAY DIFFRACTION 1.83 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	PO4, UED

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7JT0 \| pdb_00007jt0	Download File View File

Crystal structure of SARS-CoV-2 3CL protease in complex with MAC5576

Iketani, S., Forouhar, F., Liu, H., Hong, S.J., Lin, F.-Y., Nair, M.S., Zask, A., Huang, Y., Xing, L., Stockwell, B.R., Chavez, A., Ho, D.D.

(2021) Nat Commun 12: 2016-2016

Released	2021-03-10
Method	X-RAY DIFFRACTION 1.73 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	LW1, PO4

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7JT7 \| pdb_00007jt7	Download File View File

Crystal structure of SARS-CoV-2 3CL protease in complex with compound 4

Iketani, S., Forouhar, F., Liu, H., Hong, S.J., Lin, F.-Y., Nair, M.S., Zask, A., Huang, Y., Xing, L., Stockwell, B.R., Chavez, A., Ho, D.D.

(2021) Nat Commun 12: 2016-2016

Released	2021-03-17
Method	X-RAY DIFFRACTION 1.94 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	TG3

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7JW8 \| pdb_00007jw8	Download File View File

Crystal structure of SARS-CoV-2 3CL protease in complex with compound 4 in space group P1

Iketani, S., Forouhar, F., Liu, H., Hong, S.J., Lin, F.-Y., Nair, M.S., Zask, A., Xing, L., Stockwell, B.R., Chavez, A., Ho, D.D.

(2021) Nat Commun 12: 2016-2016

Released	2021-03-10
Method	X-RAY DIFFRACTION 1.84 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	BTB, TG3

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7N5H \| pdb_00007n5h	Download File View File

Cryo-EM structure of broadly neutralizing antibody 2-36 in complex with prefusion SARS-CoV-2 spike glycoprotein

Casner, R.G., Cerutti, G., Shapiro, L.

(2022) Emerg Microbes Infect 11: 147-157

Released	2021-11-03
Method	ELECTRON MICROSCOPY 3.24 Å
Organisms	Homo sapiens Severe acute respiratory syndrome coronavirus 2
Macromolecule	2-36 Fab heavy chain (protein) 2-36 Fab light chain (protein) Spike glycoprotein (protein)
Unique Ligands	NAG
Unique branched monosaccharides	NAG

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7SD5 \| pdb_00007sd5	Download File View File

Crystallographic structure of neutralizing antibody 10-40 in complex with SARS-CoV-2 spike receptor binding domain

Reddem, E.R., Casner, R.G., Shapiro, L.

(2022) Sci Transl Med 14: eabn6859-eabn6859

Released	2022-04-27
Method	X-RAY DIFFRACTION 1.53 Å
Organisms	Homo sapiens Severe acute respiratory syndrome coronavirus 2
Macromolecule	10-40 Heavy chain (protein) 10-40 Light chain (protein) Spike protein S1 (protein)
Unique branched monosaccharides	NAG

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7SI2 \| pdb_00007si2	Download File View File

Crystal structure of neutralizing antibody 10-28 in complex with SARS-CoV-2 spike receptor binding domain (RBD)

Reddem, E.R., Shapiro, L.

(2022) Sci Transl Med 14: eabn6859-eabn6859

Released	2022-04-27
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Homo sapiens Severe acute respiratory syndrome coronavirus 2
Macromolecule	10-28 Heavy Chain (protein) 10-28 Light Chain (protein) Spike protein S1 (protein)
Unique branched monosaccharides	NAG

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7TIA \| pdb_00007tia	Download File View File

Crystal structure of SARS-CoV-2 3CL in complex with inhibitor NK01-14

Forouhar, F., Liu, H., Iketani, S., Zack, A., Khanizeman, N., Bednarova, E., Fowler, B., Hong, S.J., Mohri, H., Nair, M.S., Huang, Y., Tay, N.E.S., Lee, S., Karan, C., Resnick, S.J., Quinn, C., Li, W., Shion, H., Jurtschenko, C., Lauber, M.A., McDonald, T., Stokes, M.E., Hurst, B., Rovis, T., Chavez, A., Ho, D.D., Stockwell, B.R.

(2022) Nat Commun 13: 1891-1891

Released	2022-05-04
Method	X-RAY DIFFRACTION 1.64 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase nsp5 (protein)
Unique Ligands	SCN, XTP

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7TIU \| pdb_00007tiu	Download File View File

Crystal structure of SARS-CoV-2 3CL in complex with inhibitor EB46

Forouhar, F., Liu, H., Iketani, S., Zack, A., Khanizeman, N., Bednarova, E., Fowler, B., Hong, S.J., Mohri, H., Nair, M.S., Huang, Y., Tay, N.E.S., Lee, S., Karan, C., Resnick, S.J., Quinn, C., Li, W., Shion, H., Jurtschenko, C., Lauber, M.A., McDonald, T., Stokes, M.E., Hurst, B., Rovis, T., Chavez, A., Ho, D.D., Stockwell, B.R.

(2022) Nat Commun 13: 1891-1891

Released	2022-05-04
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase nsp5 (protein)
Unique Ligands	MG, PO4, V46

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7TIV \| pdb_00007tiv	Download File View File

Crystal structure of SARS-CoV-2 3CL in complex with inhibitor EB48

Forouhar, F., Liu, H., Iketani, S., Zack, A., Khanizeman, N., Bednarova, E., Fowler, B., Hong, S.J., Mohri, H., Nair, M.S., Huang, Y., Tay, N.E.S., Lee, S., Karan, C., Resnick, S.J., Quinn, C., Li, W., Shion, H., Jurtschenko, C., Lauber, M.A., McDonald, T., Stokes, M.E., Hurst, B., Rovis, T., Chavez, A., Ho, D.D., Stockwell, B.R.

(2022) Nat Commun 13: 1891-1891

Released	2022-05-04
Method	X-RAY DIFFRACTION 2.08 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase nsp5 (protein)
Unique Ligands	MG, W48

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7TIW \| pdb_00007tiw	Download File View File

Crystal structure of SARS-CoV-2 3CL in complex with inhibitor EB54

Forouhar, F., Liu, H., Iketani, S., Zack, A., Khanizeman, N., Bednarova, E., Fowler, B., Hong, S.J., Mohri, H., Nair, M.S., Huang, Y., Tay, N.E.S., Lee, S., Karan, C., Resnick, S.J., Quinn, C., Li, W., Shion, H., Jurtschenko, C., Lauber, M.A., McDonald, T., Stokes, M.E., Hurst, B., Rovis, T., Chavez, A., Ho, D.D., Stockwell, B.R.

(2022) Nat Commun 13: 1891-1891

Released	2022-05-04
Method	X-RAY DIFFRACTION 1.68 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase nsp5 (protein)
Unique Ligands	I54, PO4

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7TIX \| pdb_00007tix	Download File View File

Crystal structure of SARS-CoV-2 3CL in complex with inhibitor EB56

Forouhar, F., Liu, H., Iketani, S., Zack, A., Khanizeman, N., Bednarova, E., Fowler, B., Hong, S.J., Mohri, H., Nair, M.S., Huang, Y., Tay, N.E.S., Lee, S., Karan, C., Resnick, S.J., Quinn, C., Li, W., Shion, H., Jurtschenko, C., Lauber, M.A., McDonald, T., Stokes, M.E., Hurst, B., Rovis, T., Chavez, A., Ho, D.D., Stockwell, B.R.

(2022) Nat Commun 13: 1891-1891

Released	2022-05-04
Method	X-RAY DIFFRACTION 2 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase nsp5 (protein)
Unique Ligands	MG, Q56

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7TIY \| pdb_00007tiy	Download File View File

Crystal structure of SARS-CoV-2 3CL in complex with inhibitor NK01-48

Forouhar, F., Liu, H., Iketani, S., Zack, A., Khanizeman, N., Bednarova, E., Fowler, B., Hong, S.J., Mohri, H., Nair, M.S., Huang, Y., Tay, N.E.S., Lee, S., Karan, C., Resnick, S.J., Quinn, C., Li, W., Shion, H., Jurtschenko, C., Lauber, M.A., McDonald, T., Stokes, M.E., Hurst, B., Rovis, T., Chavez, A., Ho, D.D., Stockwell, B.R.

(2022) Nat Commun 13: 1891-1891

Released	2022-05-04
Method	X-RAY DIFFRACTION 1.79 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase nsp5 (protein)
Unique Ligands	EDO, PO4, Y48

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7TIZ \| pdb_00007tiz	Download File View File

Crystal structure of SARS-CoV-2 3CL in complex with inhibitor NK01-63

Forouhar, F., Liu, H., Iketani, S., Zack, A., Khanizeman, N., Bednarova, E., Fowler, B., Hong, S.J., Mohri, H., Nair, M.S., Huang, Y., Tay, N.E.S., Lee, S., Karan, C., Resnick, S.J., Quinn, C., Li, W., Shion, H., Jurtschenko, C., Lauber, M.A., McDonald, T., Stokes, M.E., Hurst, B., Rovis, T., Chavez, A., Ho, D.D., Stockwell, B.R.

(2022) Nat Commun 13: 1891-1891

Released	2022-05-04
Method	X-RAY DIFFRACTION 1.55 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase nsp5 (protein)
Unique Ligands	EDO, N63, NA, SCN

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7TJ0 \| pdb_00007tj0	Download File View File

Crystal structure of SARS-CoV-2 3CL in complex with inhibitor SL-4-241

Forouhar, F., Liu, H., Iketani, S., Zack, A., Khanizeman, N., Bednarova, E., Fowler, B., Hong, S.J., Mohri, H., Nair, M.S., Huang, Y., Tay, N.E.S., Lee, S., Karan, C., Resnick, S.J., Quinn, C., Li, W., Shion, H., Jurtschenko, C., Lauber, M.A., McDonald, T., Stokes, M., Hurst, B., Rovis, T., Chavez, A., Ho, D.D., Stockwell, B.R.

(2022) Nat Commun 13: 1891-1891

Released	2022-05-04
Method	X-RAY DIFFRACTION 2.17 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase nsp5 (protein)
Unique Ligands	ACT, S4L

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7TTM \| pdb_00007ttm	Download File View File

Crystal structure of potent neutralizing antibody 10-40 in complex with Sarbecovirus bat SHC014 receptor-binding domain

Reddem, E.R., Shapiro, L.

(2022) Sci Transl Med 14: eabn6859-eabn6859

Released	2022-04-27
Method	X-RAY DIFFRACTION 2.24 Å
Organisms	Bat SARS-like coronavirus RsSHC014 Homo sapiens
Macromolecule	1040 heavy chain (protein) 1040 light chain (protein) Spike protein S1 (protein)
Unique Ligands	NAG

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7TTX \| pdb_00007ttx	Download File View File

Crystal structure of potent neutralizing antibody 10-40 in complex with Sarbecovirus bat RaTG13 receptor-binding domain

Reddem, E.R., Shapiro, L.

(2022) Sci Transl Med 14: eabn6859-eabn6859

Released	2022-04-27
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Bat coronavirus RaTG13 Homo sapiens
Macromolecule	1040 heavy chain (protein) 1040 light chain (protein) Spike glycoprotein (protein)
Unique Ligands	NAG

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7TTY \| pdb_00007tty	Download File View File

Crystal structure of potent neutralizing antibody 10-40 in complex with bat WIV1 receptor-binding domain

Reddem, E.R., Shapiro, L.

(2022) Sci Transl Med 14: eabn6859-eabn6859

Released	2022-05-04
Method	X-RAY DIFFRACTION 3.11 Å
Organisms	Bat SARS-like coronavirus WIV1 Homo sapiens
Macromolecule	1040 heavy chain (protein) 1040 light chain (protein) Spike protein S1 (protein)
Unique branched monosaccharides	NAG

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7UKL \| pdb_00007ukl	Download File View File

Cryo-EM structure of Antibody 12-16 in complex with prefusion SARS-CoV-2 Spike glycoprotein

Casner, R.G., Shapiro, L.

(2023) Immunity 56: 2442

Released	2023-10-04
Method	ELECTRON MICROSCOPY 3.09 Å
Organisms	Homo sapiens Severe acute respiratory syndrome coronavirus 2
Macromolecule	12-16 Fab Heavy Chain (protein) 12-16 Fab Light Chain (protein) Spike glycoprotein (protein)
Unique Ligands	NAG

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8H3G \| pdb_00008h3g	Download File View File

Crystal Structure of SARS-CoV-2 Main Protease (Mpro) E166V Mutant in Complex with Inhibitor Enstrelvir

Wang, H., Lin, M., Duan, Y., Zhang, X., Zhou, H., Bian, Q., Liu, X., Rao, Z., Yang, H.

(2023) Nature 622: 376-382

Released	2023-10-11
Method	X-RAY DIFFRACTION 1.46 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase nsp5 (protein)
Unique Ligands	7YY, GOL

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8H3K \| pdb_00008h3k	Download File View File

Crystal Structure of SARS-CoV-2 Main Protease (Mpro) Double Mutant (L50F and E166V) in Complex with Inhibitor Enstrelvir

Wang, H., Lin, M., Duan, Y., Zhang, X., Zhou, H., Bian, Q., Liu, X., Rao, Z., Yang, H.

(2023) Nature 622: 376-382

Released	2023-10-11
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase nsp5 (protein)
Unique Ligands	7YY, GOL, VIB

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8H3L \| pdb_00008h3l	Download File View File

Crystal Structure of SARS-CoV-2 Main Protease (Mpro) Double Mutant (T21I and E166V) in Complex with Inhibitor Enstrelvir

Wang, H., Lin, M., Duan, Y., Zhang, X., Zhou, H., Bian, Q., Liu, X., Rao, Z., Yang, H.

(2023) Nature 622: 376-382

Released	2023-10-11
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase nsp5 (protein)
Unique Ligands	7YY

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Scientific Name of Source Organism

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Experimental Method

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Refinement Resolution (Å)

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Enzyme Classification Name

Symmetry Type

SCOP Classification

3JCX | pdb_00003jcx

6I3H | pdb_00006i3h

7JST | pdb_00007jst

7JSU | pdb_00007jsu

7JT0 | pdb_00007jt0

7JT7 | pdb_00007jt7

7JW8 | pdb_00007jw8

7N5H | pdb_00007n5h

7SD5 | pdb_00007sd5

7SI2 | pdb_00007si2

7TIA | pdb_00007tia

7TIU | pdb_00007tiu

7TIV | pdb_00007tiv

7TIW | pdb_00007tiw

7TIX | pdb_00007tix

7TIY | pdb_00007tiy

7TIZ | pdb_00007tiz

7TJ0 | pdb_00007tj0

7TTM | pdb_00007ttm

7TTX | pdb_00007ttx

7TTY | pdb_00007tty

7UKL | pdb_00007ukl

8H3G | pdb_00008h3g

8H3K | pdb_00008h3k

8H3L | pdb_00008h3l