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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Malito, E."

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Search Summary

This query matches 66 Structures.

Refinements

Structure Determination Methodology

experimental (66)

Scientific Name of Source Organism

	Homo sapiens (24)
	Neisseria meningitidis (8)
	Mus musculus (5)
	Human immunodeficiency virus 1 (4)
	Neisseria meningitidis serogroup B (4)
	Streptococcus pneumoniae TIGR4 (4)
	Zea mays (4)
	synthetic construct (4)
	Human herpesvirus 5 strain 5508 (3)
	Human herpesvirus 5 strain AD169 (3)

More...

Taxonomy

	Bacteria (36)
	Eukaryota (33)
	Riboviria (7)
	Duplodnaviria (6)
	other sequences (4)

Experimental Method

	X-RAY DIFFRACTION (65)
	ELECTRON MICROSCOPY (1)

Polymer Entity Type

Protein (66)

Refinement Resolution (Å)

	1.0 - 1.5 (7)
	1.5 - 2.0 (18)
	2.0 - 2.5 (12)
	2.5 - 3.0 (18)
	3.0 - 3.5 (5)
	3.5 - 4.0 (3)
	4.0 - 4.5 (2)
	> 4.5 (1)

Release Date

	2000 - 2004 (5)
	2005 - 2009 (14)
	2010 - 2014 (17)
	2015 - 2019 (18)
	2020 - 2024 (11)
	2025 - 2029 (1)

Enzyme Classification Name

	Transferases (7)
	Hydrolases (7)
	Oxidoreductases (5)

Membrane Protein Annotation

OPM (1)

Symmetry Type

	Asymmetric (48)
	Cyclic (21)

SCOP Classification

	All beta proteins (14)
	Alpha and beta proteins (a+b) (9)
	Alpha and beta proteins (a/b) (5)
	Membrane and cell surface proteins and peptides (3)
	Artifacts (1)

AllSelected

1 to 25 of 66 Structures

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1W1O \| pdb_00001w1o	Download File View File

Native Cytokinin Dehydrogenase

Malito, E., Mattevi, A.

(2004) J Mol Biology 341: 1237

Released	2004-08-26
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Zea mays
Macromolecule	CYTOKININ DEHYDROGENASE 1 (protein)
Unique Ligands	FAD, NAG
Unique branched monosaccharides	NAG

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1W1Q \| pdb_00001w1q	Download File View File

Plant Cytokinin Dehydrogenase in Complex with Isopentenyladenine

Malito, E., Mattevi, A.

(2004) J Mol Biology 341: 1237

Released	2004-08-26
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Zea mays
Macromolecule	CYTOKININ DEHYDROGENASE 1 (protein)
Unique Ligands	FAD, NAG, ZIP
Unique branched monosaccharides	NAG

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1W1R \| pdb_00001w1r	Download File View File

Plant Cytokinin Dehydrogenase in Complex with trans-Zeatin

Malito, E., Mattevi, A.

(2004) J Mol Biology 341: 1237

Released	2004-08-26
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Zea mays
Macromolecule	CYTOKININ DEHYDROGENASE 1 (protein)
Unique Ligands	FAD, NAG, ZEA
Unique branched monosaccharides	NAG

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1W1S \| pdb_00001w1s	Download File View File

Plant Cytokinin Dehydrogenase in Complex with Benzylaminopurine

Malito, E., Mattevi, A.

(2004) J Mol Biology 341: 1237

Released	2004-08-26
Method	X-RAY DIFFRACTION 2 Å
Organisms	Zea mays
Macromolecule	CYTOKININ DEHYDROGENASE (protein)
Unique Ligands	EMU, FAD, NAG
Unique branched monosaccharides	NAG

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1W4X \| pdb_00001w4x	Download File View File

Phenylacetone Monooxygenase, a Baeyer-Villiger Monooxygenase

Malito, E., Alfieri, A., Mattevi, A.

(2004) Proc Natl Acad Sci U S A 101: 13157

Released	2004-09-02
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Thermobifida fusca
Macromolecule	PHENYLACETONE MONOOXYGENASE (protein)
Unique Ligands	FAD, SO4

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2CKO \| pdb_00002cko	Download File View File

Crystal structure of Human Choline Kinase alpha 2

Malito, E., Lavie, A.

(2006) J Mol Biology 364: 136

Released	2006-10-04
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Homo sapiens
Macromolecule	CHOLINE KINASE ALPHA (protein)
Unique Ligands	DTT

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2CKP \| pdb_00002ckp	Download File View File

Crystal structure of Human Choline Kinase alpha-2 in complex with ADP

Malito, E., Lavie, A.

(2006) J Mol Biology 364: 136

Released	2006-10-04
Method	X-RAY DIFFRACTION 3.1 Å
Organisms	Homo sapiens
Macromolecule	CHOLINE KINASE ALPHA (protein)
Unique Ligands	ADP

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2CKQ \| pdb_00002ckq	Download File View File

Crystal structure of Human Choline Kinase alpha 2 in complex with Phosphocholine

Malito, E., Lavie, A.

(2006) J Mol Biology 364: 136

Released	2006-10-04
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	CHOLINE KINASE ALPHA (protein)
Unique Ligands	PC

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2J9J \| pdb_00002j9j	Download File View File

Atomic-resolution Crystal Structure of Chemically-Synthesized HIV-1 Protease Complexed with Inhibitor JG-365

Malito, E., Shen, Y., Johnson, E.C.B., Tang, W.J.

(2007) J Mol Biology 373: 573

Released	2007-08-28
Method	X-RAY DIFFRACTION 1.04 Å
Organisms	Human immunodeficiency virus 1 synthetic construct
Macromolecule	INHIBITOR MOLECULE JG365 (protein) PROTEASE (protein)
Unique Ligands	ACT, GOL, SO4

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2J9K \| pdb_00002j9k	Download File View File

Atomic-resolution Crystal Structure of Chemically-Synthesized HIV-1 Protease Complexed with Inhibitor MVT-101

Malito, E., Shen, Y., Johnson, E.C.B., Tang, W.J.

(2007) J Mol Biology 373: 573

Released	2007-08-28
Method	X-RAY DIFFRACTION 1.2 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	PROTEASE (protein)
Unique Ligands	2NC, ACT, GOL, SO4

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2JE4 \| pdb_00002je4	Download File View File

Atomic-resolution crystal structure of chemically-synthesized HIV-1 protease in complex with JG-365

Malito, E., Johnson, E.C.B., Tang, W.J.

(2007) J Am Chem Soc 129: 11480

Released	2007-08-28
Method	X-RAY DIFFRACTION 1.07 Å
Organisms	Human immunodeficiency virus 1 synthetic construct
Macromolecule	INHIBITOR MOLECULE JG365 (protein) PROTEASE (protein)
Unique Ligands	ACT, GOL, SO4

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2JG4 \| pdb_00002jg4	Download File View File

Substrate-free IDE structure in its closed conformation

Malito, E., Tang, W.J.

(2007) J Biological Chem 282: 25453

Released	2007-07-03
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	INSULIN DEGRADING ENZYME (protein)
Unique Ligands	DIO, ZN

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2VQ7 \| pdb_00002vq7	Download File View File

Bacterial flavin-containing monooxygenase in complex with NADP: native data

Alfieri, A., Malito, E., Orru, R., Fraaije, M.W., Mattevi, A.

(2008) Proc Natl Acad Sci U S A 105: 6572

Released	2008-04-22
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Methylophaga aminisulfidivorans
Macromolecule	FLAVIN-CONTAINING MONOOXYGENASE (protein)
Unique Ligands	CL, EPE, FAD, NAP, PG4, PGE

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2VQB \| pdb_00002vqb	Download File View File

Bacterial flavin-containing monooxygenase in complex with NADP: soaking in aerated solution

Alfieri, A., Malito, E., Orru, R., Fraaije, M.W., Mattevi, A.

(2008) Proc Natl Acad Sci U S A 105: 6572

Released	2008-04-22
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Methylophaga aminisulfidivorans
Macromolecule	FLAVIN-CONTAINING MONOOXYGENASE (protein)
Unique Ligands	CL, EPE, FAD, NAP, OXY

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2WBY \| pdb_00002wby	Download File View File

Crystal structure of human insulin-degrading enzyme in complex with insulin

Manolopoulou, M., Guo, Q., Malito, E., Schilling, A.B., Tang, W.J.

(2009) J Biological Chem 284: 14177

Released	2009-03-24
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	INSULIN A CHAIN (protein) INSULIN B CHAIN (protein) INSULIN-DEGRADING ENZYME (protein)
Unique Ligands	ZN

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2WC0 \| pdb_00002wc0	Download File View File

crystal structure of human insulin degrading enzyme in complex with iodinated insulin

Manolopoulou, M., Guo, Q., Malito, E., Schilling, A.B., Tang, W.J.

(2009) J Biological Chem 284: 14177

Released	2009-03-24
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	INSULIN A CHAIN (protein) INSULIN B CHAIN (protein) INSULIN-DEGRADING ENZYME (protein)
Unique Ligands	DIO, ZN

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2X9W \| pdb_00002x9w	Download File View File

STRUCTURE OF THE PILUS BACKBONE (RRGB) FROM STREPTOCOCCUS PNEUMONIAE

Spraggon, G., Koesema, E., Scarselli, M., Malito, E., Biagini, M., Norais, N., Emolo, C., Barocchi, M.A., Giusti, F., Hilleringmann, M., Rappuoli, R., Lesley, S., Covacci, A., Masignani, V., Ferlenghi, I.

(2010) PLoS One 5: 919

Released	2010-06-30
Method	X-RAY DIFFRACTION 1.92 Å
Organisms	Streptococcus pneumoniae TIGR4
Macromolecule	CELL WALL SURFACE ANCHOR FAMILY PROTEIN (protein)
Unique Ligands	GOL

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2X9X \| pdb_00002x9x	Download File View File

STRUCTURE OF THE PILUS BACKBONE (RRGB) FROM STREPTOCOCCUS PNEUMONIAE

(2010) PLoS One 5: 919

Released	2010-06-30
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Streptococcus pneumoniae TIGR4
Macromolecule	CELL WALL SURFACE ANCHOR FAMILY PROTEIN (protein)
Unique Ligands	IMD, NA

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2X9Y \| pdb_00002x9y	Download File View File

STRUCTURE OF THE PILUS BACKBONE (RRGB) FROM STREPTOCOCCUS PNEUMONIAE

(2010) PLoS One 5: 919

Released	2010-06-30
Method	X-RAY DIFFRACTION 2.33 Å
Organisms	Streptococcus pneumoniae TIGR4
Macromolecule	CELL WALL SURFACE ANCHOR FAMILY PROTEIN (protein)

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2X9Z \| pdb_00002x9z	Download File View File

STRUCTURE OF THE PILUS BACKBONE (RRGB) FROM STREPTOCOCCUS PNEUMONIAE

(2010) PLoS One 5: 919

Released	2010-06-30
Method	X-RAY DIFFRACTION 1.3 Å
Organisms	Streptococcus pneumoniae TIGR4
Macromolecule	CELL WALL SURFACE ANCHOR FAMILY PROTEIN (protein)

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2Y7S \| pdb_00002y7s	Download File View File

Structure of a designed meningococcal antigen (factor H binding protein, mutant G1) inducing broad protective immunity

Malito, E., Spraggon, G., Bottomley, M.J.

(2011) Sci Transl Med 3: 91RA6

Released	2011-07-27
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Neisseria meningitidis MC58
Macromolecule	FACTOR H BINDING PROTEIN (protein)

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2YPV \| pdb_00002ypv	Download File View File

Crystal structure of the Meningococcal vaccine antigen factor H binding protein in complex with a bactericidal antibody

Malito, E., Veggi, D., Bottomley, M.J.

(2013) Proc Natl Acad Sci U S A 110: 3304

Released	2013-02-20
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Mus musculus Neisseria meningitidis MC58
Macromolecule	FAB 12C1 (protein) LIPOPROTEIN (protein)
Unique Ligands	EDO

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3CQF \| pdb_00003cqf	Download File View File

Crystal structure of anthrolysin O (ALO)

Bourdeau, R.W., Malito, E., Tang, W.J.

(2009) J Biological Chem 284: 14645-14656

Released	2009-03-17
Method	X-RAY DIFFRACTION 3.1 Å
Organisms	Bacillus anthracis
Macromolecule	Thiol-activated cytolysin (protein)

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3CWW \| pdb_00003cww	Download File View File

Crystal Structure of IDE-bradykinin complex

Malito, E., Tang, W.J.

(2008) Biochemistry 47: 12822-12834

Released	2008-11-25
Method	X-RAY DIFFRACTION 1.96 Å
Organisms	Homo sapiens
Macromolecule	Insulin-degrading enzyme (protein) bradykinin N-terminal tetrapeptide analogue (protein)
Unique Ligands	ACT, DIO, ZN

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3E4A \| pdb_00003e4a	Download File View File

Human IDE-inhibitor complex at 2.6 angstrom resolution

Malito, E., Leissring, M.A., Choi, S., Cuny, G.D., Tang, W.J.

(2010) PLoS One 5: e10504-e10504

Released	2009-05-19
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens synthetic construct
Macromolecule	HYDROXAMATE PEPTIDE II1 (protein) Insulin-degrading enzyme (protein)
Unique Ligands	ACY, DIO, QIX, ZN

1 to 25 of 66 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1W1O | pdb_00001w1o

1W1Q | pdb_00001w1q

1W1R | pdb_00001w1r

1W1S | pdb_00001w1s

1W4X | pdb_00001w4x

2CKO | pdb_00002cko

2CKP | pdb_00002ckp

2CKQ | pdb_00002ckq

2J9J | pdb_00002j9j

2J9K | pdb_00002j9k

2JE4 | pdb_00002je4

2JG4 | pdb_00002jg4

2VQ7 | pdb_00002vq7

2VQB | pdb_00002vqb

2WBY | pdb_00002wby

2WC0 | pdb_00002wc0

2X9W | pdb_00002x9w

2X9X | pdb_00002x9x

2X9Y | pdb_00002x9y

2X9Z | pdb_00002x9z

2Y7S | pdb_00002y7s

2YPV | pdb_00002ypv

3CQF | pdb_00003cqf

3CWW | pdb_00003cww

3E4A | pdb_00003e4a