RCSB PDB: Search

Warning You are using a web browser that we do not support. Our website will not work properly. Please update to a newer version or download a new web browser, such as Chrome or Firefox.

Help

Help

RCSB PDB

Deposit
- PDBx/mmCIF file
- pdb_extract
- SF-Tool
- Ligand Expo
- MAXIT
- Validation Server
- Validation API
- Information for Journals
- Validation Task Forces
- wwPDB OneDep System
- PDB-IHM
Search
Visualize
Analyze
Download
Learn
- Training Courses
- Guide to PDB Data
- Molecule of the Month
- Educational Resources
- Curricula
- Browse
- News
- SciArt Galleries
- Irving Geis
- David Goodsell
About
Careers
COVID-19

233,249 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

	Include CSM
Advanced Search \| Browse Annotations		Help

Search
Query History
Browse Annotations
MyPDB

QUERY: Structure Author = "Jowitt, T.A."

MyPDB Login

Search API

Advanced Search Query Builder

Help

Full Text

Structure Attributes

Help

NOT

Count

Add Subquery

Chemical Attributes

Sequence Similarity

Sequence Motif

Structure Similarity

Structure Motif

Chemical Similarity

Return

grouped by

Include Computed Structure Models (CSM)

Count

Clear

Search Summary

This query matches 8 Structures.

Refinements

Structure Determination Methodology

experimental (8)

Scientific Name of Source Organism

	Homo sapiens (5)
	Human alphaherpesvirus 1 (2)
	Human alphaherpesvirus 1 strain 17 (2)

Taxonomy

	Eukaryota (5)
	Duplodnaviria (3)

Experimental Method

X-RAY DIFFRACTION (8)

Polymer Entity Type

	Protein (8)
	DNA (2)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (2)
	2.0 - 2.5 (4)
	2.5 - 3.0 (1)

Release Date

	2005 - 2009 (3)
	2015 - 2019 (5)

Enzyme Classification Name

Transferases (1)

Symmetry Type

	Asymmetric (4)
	Cyclic (4)

SCOP Classification

	All alpha proteins (2)
	Artifacts (2)
	Alpha and beta proteins (a+b) (1)

AllSelected

1 to 8 of 8 Structures

Page 1 of 1

Sort by

Explore in 3D

2O2K \| pdb_00002o2k	Download File View File

Crystal Structure of the Activation Domain of Human Methionine Synthase Isoform/Mutant D963E/K1071N

Wolthers, K.R., Toogood, H.S., Jowitt, T.A., Marshall, K.R., Leys, D., Scrutton, N.S.

(2007) FEBS J 274: 738-750

Released	2006-12-19
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Homo sapiens
Macromolecule	Methionine synthase (protein)

Explore in 3D

2UWN \| pdb_00002uwn	Download File View File

Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand.

Prosser, B.E., Johnson, S., Roversi, P., Herbert, A.P., Blaum, B.S., Tyrrell, J., Jowitt, T.A., Clark, S.J., Terelli, E., Uhrin, D., Barlow, P.N., Sim, R.B., Day, A.J., Lea, S.M.

(2007) J Exp Medicine 204: 2277

Released	2007-10-02
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Homo sapiens
Macromolecule	HUMAN COMPLEMENT FACTOR H (protein)
Unique Ligands	ACT, CL, SO4
Unique branched monosaccharides	GU4, YYJ

Explore in 3D

2V8E \| pdb_00002v8e	Download File View File

Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand.

Prosser, B.E., Johnson, S., Roversi, P., Herbert, A.P., Blaum, B.S., Tyrrell, J., Jowitt, T.A., Clark, S.J., Tarelli, E., Uhrin, D., Barlow, P.N., Sim, R.B., Day, A.J., Lea, S.M.

(2007) J Exp Medicine 204: 2277

Released	2007-10-02
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	COMPLEMENT FACTOR H (protein)
Unique Ligands	CL, GOL, SO4
Unique branched monosaccharides	GU4, YYJ

Explore in 3D

4YXP \| pdb_00004yxp	Download File View File

The structure of the folded domain of the signature multifunctional protein ICP27 from herpes simplex virus-1 reveals an intertwined dimer.

Tunnicliffe, R.B., Schacht, M., Levy, C.W., Jowitt, T.A., Sandri-Goldin, R.M., Golovanov, A.P.

(2015) Sci Rep 5: 11234-11234

Released	2015-06-17
Method	X-RAY DIFFRACTION 1.92 Å
Organisms	Human alphaherpesvirus 1 strain 17
Macromolecule	mRNA export factor (protein)
Unique Ligands	ZN

Explore in 3D

5AD2 \| pdb_00005ad2	Download File View File

Bivalent binding to BET bromodomains

Waring, M.J., Chen, H., Rabow, A.A., Walker, G., Bobby, R., Boiko, S., Bradbury, R.H., Callis, R., Dale, I., Daniels, D., Flavell, L., Holdgate, G., Jowitt, T.A., Kikhney, A., McAlister, M., Ogg, D., Patel, J., Petteruti, P., Robb, G.R., Robers, M., Stratton, N., Svergun, D.I., Wang, W., Whittaker, D.

(2016) Nat Chem Biol 12: 1097

Released	2016-09-28
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Homo sapiens
Macromolecule	BROMODOMAIN-CONTAINING PROTEIN 4 (protein)
Unique Ligands	ETU

Explore in 3D

5AD3 \| pdb_00005ad3	Download File View File

Bivalent binding to BET bromodomains

(2016) Nat Chem Biol 12: 1097

Released	2016-09-28
Method	X-RAY DIFFRACTION 1.49 Å
Organisms	Homo sapiens
Macromolecule	BROMODOMAIN-CONTAINING PROTEIN 4 (protein)
Unique Ligands	K6K

Explore in 3D

5MHJ \| pdb_00005mhj	Download File View File

ICP4 DNA-binding domain, lacking intrinsically disordered region, in complex with 12mer DNA duplex from its own promoter

Tunnicliffe, R.B., Lockhart-Cairns, M.P., Levy, C., Mould, P., Jowitt, T.A., Sito, H., Baldock, C., Sandri-Goldin, R.M., Golovanov, A.P.

(2017) Nucleic Acids Res 45: 8064-8078

Released	2017-05-24
Method	X-RAY DIFFRACTION 2.117 Å
Organisms	Human alphaherpesvirus 1 Human alphaherpesvirus 1 strain 17
Macromolecule	Major viral transcription factor ICP4 (protein) DNA (5'-D(PCPGPAPTPCPGPTPCP*C)-3') (nucleic acid)
Unique Ligands	ACY, CL

Explore in 3D

5MHK \| pdb_00005mhk	Download File View File

ICP4 DNA-binding domain in complex with 19mer DNA duplex from its own promoter

Tunnicliffe, R.B., Lockhart-Cairns, M.P., Levy, C., Mould, P., Jowitt, T.A., Sito, H., Baldock, C., Sandri-Goldin, R.M., Golovanov, A.P.

(2017) Nucleic Acids Res 45: 8064-8078

Released	2017-05-24
Method	X-RAY DIFFRACTION 2.28 Å
Organisms	Human alphaherpesvirus 1
Macromolecule	ICP4 DNA BINDING DOMAIN (protein) RS1 (protein) DNA (5'-D(GPCPTPCPCPGPTPGPTPGPGPAPCPGPAPTPCPGP*G)-3') (nucleic acid)
Unique Ligands	CL, MG, SO4

1 to 8 of 8 Structures

Page 1 of 1

Sort by

About
About Us
Citing Us
Publications
Team
Careers
Usage & Privacy

Support
Contact Us
Help
Website FAQ
Glossary
Service Status

RCSB PDB is hosted by

RCSB PDB is a member of the

RCSB Partners
Nucleic Acid Knowledgebase

wwPDB Partners
RCSB PDB
PDBe
PDBj
BMRB
EMDB

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

2O2K | pdb_00002o2k

Crystal Structure of the Activation Domain of Human Methionine Synthase Isoform/Mutant D963E/K1071N

2UWN | pdb_00002uwn

Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand.

2V8E | pdb_00002v8e

Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand.

4YXP | pdb_00004yxp

The structure of the folded domain of the signature multifunctional protein ICP27 from herpes simplex virus-1 reveals an intertwined dimer.

5AD2 | pdb_00005ad2

Bivalent binding to BET bromodomains

5AD3 | pdb_00005ad3

Bivalent binding to BET bromodomains

5MHJ | pdb_00005mhj

ICP4 DNA-binding domain, lacking intrinsically disordered region, in complex with 12mer DNA duplex from its own promoter

5MHK | pdb_00005mhk

ICP4 DNA-binding domain in complex with 19mer DNA duplex from its own promoter

Prepare Data

Validate Data

Deposit Data

Help and Resources

Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

2O2K | pdb_00002o2k

2UWN | pdb_00002uwn

2V8E | pdb_00002v8e

4YXP | pdb_00004yxp

5AD2 | pdb_00005ad2

5AD3 | pdb_00005ad3

5MHJ | pdb_00005mhj

5MHK | pdb_00005mhk