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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Hu, Q."

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Search Summary

This query matches 99 Structures.

Refinements

Structure Determination Methodology

experimental (99)

Scientific Name of Source Organism

	Homo sapiens (72)
	Severe acute respiratory syndrome coronavirus 2 (10)
	Arabidopsis thaliana (4)
	Acinetobacter baumannii NIPH 410 (2)
	Equus caballus (2)
	Phytophthora infestans T30-4 (2)
	Saccharomyces cerevisiae S288C (2)
	Sulfitobacter sp. NAS-14.1 (2)
	synthetic construct (2)
	Glycine soja (1)

More...

Taxonomy

	Eukaryota (82)
	Riboviria (12)
	Bacteria (5)
	other sequences (2)
	Duplodnaviria (1)

Experimental Method

	X-RAY DIFFRACTION (47)
	ELECTRON MICROSCOPY (43)
	SOLUTION NMR (9)

Polymer Entity Type

	Protein (99)
	DNA (24)
	RNA (1)

Refinement Resolution (Å)

	1.5 - 2.0 (23)
	2.0 - 2.5 (14)
	2.5 - 3.0 (13)
	3.0 - 3.5 (18)
	3.5 - 4.0 (19)
	4.0 - 4.5 (3)

Release Date

	2005 - 2009 (2)
	2010 - 2014 (7)
	2015 - 2019 (14)
	2020 - 2024 (74)
	2025 - 2029 (2)

Enzyme Classification Name

	Transferases (39)
	Hydrolases (19)
	Ligases (11)

Membrane Protein Annotation

	PDBTM (7)
	MemProtMD (4)
	OPM (1)

Symmetry Type

	Asymmetric (73)
	Cyclic (26)
	Dihedral (3)

SCOP Classification

	All alpha proteins (4)
	Artifacts (4)
	Alpha and beta proteins (a+b) (4)
	All beta proteins (2)
	Small proteins (1)

AllSelected

1 to 25 of 99 Structures

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2KXJ \| pdb_00002kxj	Download File View File

Solution structure of UBX domain of human UBXD2 protein

Wu, Q., Huang, H., Zhang, J., Hu, Q., Wu, J., Shi, Y.

To be published

Released	2011-05-18
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	UBX domain-containing protein 4 (protein)

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2LH0 \| pdb_00002lh0	Download File View File

NMR structure of the histone-interacting N-terminal homodimeric region of Rtt106

Hu, Q., Cui, G., Mer, G.

(2012) Nature 483: 104-107

Released	2012-02-01
Method	SOLUTION NMR
Organisms	Saccharomyces cerevisiae S288C
Macromolecule	Histone chaperone RTT106 (protein)

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2OMJ \| pdb_00002omj	Download File View File

solution structure of LARG PDZ domain

Liu, J., Huang, H., Hu, Q.

To be published

Released	2008-01-22
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Rho guanine nucleotide exchange factor 12 (protein)

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2PPH \| pdb_00002pph	Download File View File

solution structure of human MEKK3 PB1 domain

Hu, Q., Zhang, J., Wu, J., Shi, Y.

(2007) Biochemistry 46: 13478-13489

Released	2007-05-22
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Mitogen-activated protein kinase kinase kinase 3 (protein)

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3JBT \| pdb_00003jbt	Download File View File

Atomic structure of the Apaf-1 apoptosome

Zhou, M., Li, Y., Hu, Q., Bai, X., Huang, W., Yan, C., Scheres, S.H.W., Shi, Y.

(2015) Genes Dev 29: 2349-2361

Released	2015-11-18
Method	ELECTRON MICROSCOPY 3.8 Å
Organisms	Equus caballus Homo sapiens
Macromolecule	Apoptotic protease-activating factor 1 (protein) Cytochrome c (protein)
Unique Ligands	DTP, HEM, MG

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4DNU \| pdb_00004dnu	Download File View File

Crystal structure of the W285A mutant of UVB-resistance protein UVR8

Wu, D., Hu, Q., Yan, Z., Chen, W., Yan, C., Zhang, J., Wang, J., Shi, Y.

(2012) Nature 484: 214-219

Released	2012-03-07
Method	X-RAY DIFFRACTION 1.764 Å
Organisms	Arabidopsis thaliana
Macromolecule	AT5g63860/MGI19_6 (protein)

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4DNV \| pdb_00004dnv	Download File View File

Crystal structure of the W285F mutant of UVB-resistance protein UVR8

Wu, D., Hu, Q., Yan, Z., Chen, W., Yan, C., Zhang, J., Wang, J., Shi, Y.

(2012) Nature 484: 214-219

Released	2012-03-07
Method	X-RAY DIFFRACTION 1.999 Å
Organisms	Arabidopsis thaliana
Macromolecule	AT5g63860/MGI19_6 (protein)

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4DNW \| pdb_00004dnw	Download File View File

Crystal structure of UVB-resistance protein UVR8

Wu, D., Hu, Q., Yan, Z., Chen, W., Yan, C., Wang, J., Shi, Y.

(2012) Nature 484: 214-219

Released	2012-03-07
Method	X-RAY DIFFRACTION 1.773 Å
Organisms	Arabidopsis thaliana
Macromolecule	AT5g63860/MGI19_6 (protein)

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4RHW \| pdb_00004rhw	Download File View File

Crystal structure of Apaf-1 CARD and caspase-9 CARD complex

Hu, Q., Wu, D., Yan, C., Shi, Y.

(2014) Proc Natl Acad Sci U S A 111: 16254-16261

Released	2014-10-15
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Apoptotic protease-activating factor 1 (protein) Caspase-9 (protein)
Unique Ligands	CL, SO4

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4RNG \| pdb_00004rng	Download File View File

Crystal structure of a bacterial homologue of SWEET transporters

Hu, Q., Wang, J., Yan, C., Yan, N.

(2014) Cell Res 24: 1486-1489

Released	2014-11-19
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Thermodesulfovibrio yellowstonii DSM 11347
Macromolecule	MtN3/saliva family (protein)
Unique Ligands	OLC, SO4

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5KN7 \| pdb_00005kn7	Download File View File

Lipid A secondary acyltransferase LpxM from Acinetobacter baumannii

Dovala, D.L., Hu, Q., Metzger IV, L.E.

(2016) Proc Natl Acad Sci U S A 113: E6064-E6071

Released	2016-09-28
Method	X-RAY DIFFRACTION 1.99 Å
Organisms	Acinetobacter baumannii NIPH 410
Macromolecule	Lipid A biosynthesis lauroyl acyltransferase (protein)
Unique Ligands	GOL, LMT, NA, PO4, SO4

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5KNK \| pdb_00005knk	Download File View File

Lipid A secondary acyltransferase LpxM from Acinetobacter baumannii with catalytic residue substitution (E127A)

Dovala, D.L., Hu, Q., Metzger IV, L.E.

(2016) Proc Natl Acad Sci U S A 113: E6064-E6071

Released	2016-09-28
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Acinetobacter baumannii NIPH 410
Macromolecule	Lipid A biosynthesis lauroyl acyltransferase (protein)
Unique Ligands	11A, GOL, LMT, SO4

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5UMR \| pdb_00005umr	Download File View File

Crystal structure of N-terminal domain of human FACT complex subunit SSRP1

Su, D., Hu, Q., Thompson, J.R., Heroux, A., Botuyan, M.V., Mer, G.

To be published

Released	2018-01-31
Method	X-RAY DIFFRACTION 1.501 Å
Organisms	Homo sapiens
Macromolecule	FACT complex subunit SSRP1 (protein)

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5UMS \| pdb_00005ums	Download File View File

Crystal structure of middle double PH domain of human FACT complex subunit SSRP1

Su, D., Hu, Q., Thompson, J.R., Botuyan, M.V., Mer, G.

To be published

Released	2018-01-31
Method	X-RAY DIFFRACTION 1.569 Å
Organisms	Homo sapiens
Macromolecule	FACT complex subunit SSRP1 (protein)

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5UMT \| pdb_00005umt	Download File View File

Crystal structure of N-terminal domain of human FACT complex subunit SPT16

Su, D., Hu, Q., Thompson, J.R., Botuyan, M.V., Mer, G.

To be published

Released	2018-01-31
Method	X-RAY DIFFRACTION 2.092 Å
Organisms	Homo sapiens
Macromolecule	FACT complex subunit SPT16 (protein)
Unique Ligands	EDO, GOL

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5UMU \| pdb_00005umu	Download File View File

Crystal structure of the middle double PH domain of human FACT complex subunit SPT16

Hu, Q., Thompson, J.R., Heroux, A., Su, D., Botuyan, M.V., Mer, G.

To be published

Released	2018-01-31
Method	X-RAY DIFFRACTION 1.903 Å
Organisms	Homo sapiens
Macromolecule	FACT complex subunit SPT16 (protein)
Unique Ligands	ACT, FMT

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5VEY \| pdb_00005vey	Download File View File

Solution NMR structure of histone H2A-H2B mono-ubiquitylated at H2A Lys15 in complex with RNF169 (653-708)

Hu, Q., Botuyan, M.V., Cui, G., Mer, G.

(2017) Mol Cell 66: 473-487.e9

Released	2017-05-17
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	E3 ubiquitin-protein ligase RNF169 (protein) Histone H2B type 1-J,Histone H2A type 1-B/E (protein) Polyubiquitin-B (protein)

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5VF0 \| pdb_00005vf0	Download File View File

Solution NMR structure of human RAD18 (198-240) in complex with ubiquitin

Hu, Q., Botuyan, M.V., Mer, G.

(2017) Mol Cell 66: 473-487.e9

Released	2017-05-17
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	E3 ubiquitin-protein ligase RAD18 (protein) Polyubiquitin-B (protein)
Unique Ligands	ZN

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5VWE \| pdb_00005vwe	Download File View File

Solution NMR structure of the HMG domain of human FACT complex subunit SSRP1

Hu, Q., Botuyan, M.V., Mer, G.

To be published

Released	2018-05-23
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	FACT complex subunit SSRP1 (protein)

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5WVE \| pdb_00005wve	Download File View File

Apaf-1-Caspase-9 holoenzyme

Li, Y., Zhou, M., Hu, Q., Shi, Y.

(2017) Proc Natl Acad Sci U S A 114: 1542-1547

Released	2017-02-08
Method	ELECTRON MICROSCOPY 4.4 Å
Organisms	Equus caballus Homo sapiens
Macromolecule	Apoptotic protease-activating factor 1 (protein) Caspase (protein) Cytochrome c (protein)
Unique Ligands	DTP, HEM, MG

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5YFG \| pdb_00005yfg	Download File View File

SOLUTION STRUCTURE OF HUMAN MOG1

Hu, Q., Liu, Y., Bao, X., Liu, H.

(2018) J Mol Cell Biol 10: 18-32

Released	2017-11-01
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Ran guanine nucleotide release factor (protein)

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6AU6 \| pdb_00006au6	Download File View File

Crystal structure of GDP-bound human GNAS R201C mutant

Hu, Q., Shokat, K.M.

(2018) Cell 173: 1254-1264.e11

Released	2018-05-09
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (protein)
Unique Ligands	CL, GDP, GOL, MG

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6CZ5 \| pdb_00006cz5	Download File View File

Crystal structure of small molecule AMP-acrylamide covalently bound to DDX3 S228C

Barkovich, K.J., Moore, M.K., Hu, Q., Shokat, K.M.

(2018) Nucleic Acids Res 46: 8689-8699

Released	2018-08-08
Method	X-RAY DIFFRACTION 3 Å
Organisms	Homo sapiens
Macromolecule	ATP-dependent RNA helicase DDX3X (protein)
Unique Ligands	FPJ

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6WGN \| pdb_00006wgn	Download File View File

Crystal structure of K-Ras(G12D) GppNHp bound to cyclic peptide ligand KD2

Zhang, Z., Gao, R., Hu, Q., Peacock, H., Peacock, D.M., Shokat, K.M., Suga, H.

(2020) ACS Cent Sci 6: 1753-1761

Released	2020-10-14
Method	X-RAY DIFFRACTION 1.601 Å
Organisms	Homo sapiens
Macromolecule	Cyclic Peptide KD2 (protein) GTPase KRas (protein)
Unique Ligands	GNP, MG

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7BPH \| pdb_00007bph	Download File View File

Crystal structure of GppNHp-bound GNAS in complex with the cyclic peptide inhibitor GN13

Hu, Q., Dai, S., Shokat, K.M.

(2022) Cell

Released	2021-03-31
Method	X-RAY DIFFRACTION 1.57 Å
Organisms	Homo sapiens synthetic construct
Macromolecule	GN13 (protein) Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (protein)
Unique Ligands	CL, GNP, GOL, MG

1 to 25 of 99 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

2KXJ | pdb_00002kxj

2LH0 | pdb_00002lh0

2OMJ | pdb_00002omj

2PPH | pdb_00002pph

3JBT | pdb_00003jbt

4DNU | pdb_00004dnu

4DNV | pdb_00004dnv

4DNW | pdb_00004dnw

4RHW | pdb_00004rhw

4RNG | pdb_00004rng

5KN7 | pdb_00005kn7

5KNK | pdb_00005knk

5UMR | pdb_00005umr

5UMS | pdb_00005ums

5UMT | pdb_00005umt

5UMU | pdb_00005umu

5VEY | pdb_00005vey

5VF0 | pdb_00005vf0

5VWE | pdb_00005vwe

5WVE | pdb_00005wve

5YFG | pdb_00005yfg

6AU6 | pdb_00006au6

6CZ5 | pdb_00006cz5

6WGN | pdb_00006wgn

7BPH | pdb_00007bph