RCSB PDB: Search

1W85 \| pdb_00001w85	Download File View File

The crystal structure of pyruvate dehydrogenase E1 bound to the peripheral subunit binding domain of E2

Frank, R.A.W., Pratap, J.V., Pei, X.Y., Perham, R.N., Luisi, B.F.

(2004) Science 306: 872-876

Released	2004-11-02
Method	X-RAY DIFFRACTION 2 Å
Organisms	Geobacillus stearothermophilus
Macromolecule	DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE (protein) PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT (protein) PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA SUBUNIT (protein)
Unique Ligands	K, MG, PEG, TPP

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1W88 \| pdb_00001w88	Download File View File

The crystal structure of pyruvate dehydrogenase E1(D180N,E183Q) bound to the peripheral subunit binding domain of E2

Frank, R.A.W., Pratap, J.V., Pei, X.Y., Perham, R.N., Luisi, B.F.

(2004) Science 306: 872

Released	2004-11-02
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Geobacillus stearothermophilus
Macromolecule	DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE (protein) PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT (protein) PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA SUBUNIT (protein)
Unique Ligands	MG, TPP

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2BP7 \| pdb_00002bp7	Download File View File

New crystal form of the Pseudomonas putida branched-chain dehydrogenase (E1)

Frank, R.A.W., Pratap, J.V., Pei, X.Y., Perham, R.N., Luisi, B.F.

(2005) Structure 13: 1119

Released	2005-08-10
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Pseudomonas putida
Macromolecule	2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT (protein) 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT (protein)

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2JGD \| pdb_00002jgd	Download File View File

E. COLI 2-oxoglutarate dehydrogenase (E1o)

Frank, R.A.W., Price, A.J., Northrop, F.D., Perham, R.N., Luisi, B.F.

(2007) J Mol Biology 368: 639

Released	2007-02-27
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Escherichia coli K-12
Macromolecule	2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT (protein)
Unique Ligands	AMP

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3DUF \| pdb_00003duf	Download File View File

Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multi-enzyme complex

Pei, X.Y., Titman, C.M., Frank, R.A.W., Leeper, F.J., Luisi, B.F.

(2008) Structure 16: 1860-1872

Released	2009-01-06
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Geobacillus stearothermophilus
Macromolecule	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (protein) Pyruvate dehydrogenase E1 component subunit alpha (protein) Pyruvate dehydrogenase E1 component subunit beta (protein)
Unique Ligands	K, MG, R1T

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3DV0 \| pdb_00003dv0	Download File View File

Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multi-enzyme complex

Pei, X.Y., Titman, C.M., Frank, R.A.W., Leeper, F.J., Luisi, B.F.

(2008) Structure 16: 1860-1872

Released	2009-01-13
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Geobacillus stearothermophilus
Macromolecule	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (protein) Pyruvate dehydrogenase E1 component subunit alpha (protein) Pyruvate dehydrogenase E1 component subunit beta (protein)
Unique Ligands	K, MG, PYR, TPW

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3DVA \| pdb_00003dva	Download File View File

Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multi-enzyme complex

Pei, X.Y., Titman, C.M., Frank, R.A.W., Leeper, F.J., Luisi, B.F.

(2008) Structure 16: 1860-1872

Released	2009-01-13
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Geobacillus stearothermophilus
Macromolecule	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (protein) Pyruvate dehydrogenase E1 component subunit alpha (protein) Pyruvate dehydrogenase E1 component subunit beta (protein)
Unique Ligands	K, MG, TPW

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8BFA \| pdb_00008bfa	Download File View File

Sarkosyl-extracted AppNL-G-F Abeta42 fibril structure

Wilkinson, M., Leistner, C., Burgess, A., Goodfellow, S., Deuchars, S., Ranson, N.A., Radford, S.E., Frank, R.A.W.

(2023) Nat Commun 14: 2833-2833

Released	2023-05-31
Method	ELECTRON MICROSCOPY 3 Å
Organisms	Mus musculus
Macromolecule	Amyloid-beta precursor protein (protein)

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8BFB \| pdb_00008bfb	Download File View File

Sarkosyl-extracted AppNL-G-F Abeta42 fibril structure (Methoxy-X04-labelled mice)

Wilkinson, M., Leistner, C., Burgess, A., Goodfellow, S., Deuchars, S., Ranson, N.A., Radford, S.E., Frank, R.A.W.

(2023) Nat Commun 14: 2833-2833

Released	2023-05-31
Method	ELECTRON MICROSCOPY 3.2 Å
Organisms	Mus musculus
Macromolecule	Amyloid-beta precursor protein (protein)

1W85 | pdb_00001w85

The crystal structure of pyruvate dehydrogenase E1 bound to the peripheral subunit binding domain of E2

1W88 | pdb_00001w88

The crystal structure of pyruvate dehydrogenase E1(D180N,E183Q) bound to the peripheral subunit binding domain of E2

2BP7 | pdb_00002bp7

New crystal form of the Pseudomonas putida branched-chain dehydrogenase (E1)

2JGD | pdb_00002jgd

E. COLI 2-oxoglutarate dehydrogenase (E1o)

3DUF | pdb_00003duf

Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multi-enzyme complex

3DV0 | pdb_00003dv0

Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multi-enzyme complex

3DVA | pdb_00003dva

Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multi-enzyme complex

8BFA | pdb_00008bfa

Sarkosyl-extracted AppNL-G-F Abeta42 fibril structure

8BFB | pdb_00008bfb

Sarkosyl-extracted AppNL-G-F Abeta42 fibril structure (Methoxy-X04-labelled mice)

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1W85 | pdb_00001w85

1W88 | pdb_00001w88

2BP7 | pdb_00002bp7

2JGD | pdb_00002jgd

3DUF | pdb_00003duf

3DV0 | pdb_00003dv0

3DVA | pdb_00003dva

8BFA | pdb_00008bfa

8BFB | pdb_00008bfb