DrugBank ID DB00878 Name Chlorhexidine Groups approved withdrawn vet_approved Description Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms.[L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today.[A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two biguanide groups joined by a central hexamethylene chain.[A190453] Topical chlorhexidine for disinfection, as well as oral rinses for dental use, carries activity against a broad range of pathogens including bacteria, yeasts, and viruses.[L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the early 1950s[A190474] and was introduced to the US in the 1970s.[L11572] The FDA withdrew its approval for the use of chlorhexidine gluconate topical tincture 0.5%, due to a significant number of reports concerning chemical and thermal burns associated with the use of this product.[L43942,L44027] Other formulations of chlorhexidine continue to be available. Synonyms Chlorhexidine acetate Clorhexidina Chlorhexidine gluconate Chlorhexidin Chlorhexidinum
Cloresidina 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide) Chlorhexidine hydrochloride N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide Chlorhexidine more Brand Names Germi Stat Gel 2% Chlorhexidine Sterixin 0.05% Loris I.V. Pro - Swabstick Surgical Continuum System
Chinese Herb Essence Bacteriostatic Feminine Wash Oral Cleansing and Suctioning System, q4 Bactoshield CHG Chlorhexidine Gluconate Solution E-Z Scrub 747 4% Rouhex G 4% Purell Antimicrobial Foam Handwash 2% Chg Purell CS Foam Handwash 2% CHG Chlorhexidine Gluconate Applicator Chlorhexidine and Isopropyl Alcohol Swabsticks Chlorhexidine 2% Antiseptic Hand Wash Germi-stat Prep Gel DASH Chlorhexidine Gluconate 0.12% Oral Rinse Provon Antiseptic Lotion Soap With 2% Chg HandSoap Surgical and healthcare personnel hand antiseptic with moisturizers Dexidin Liq 4% Chlorhexidine Alcohol Free Microban Medical Chlora-cleanze Maxiclens Chlorhexidine Gluconate Liquid Solution, 4% Prevantics Swab E-Z Scrub Antimicrobial Foam Solution Containing 4% Chg Dexidin 0.5 Solution Quick-Drying Hand Sanitizer Foaming Hand Wash Smart San CHG Dyural LM- C Henry Schein Antimicrobial Skin Cleanser (Fruli) Quick-Dry Disposable Hand Sanitizer Scrub Care Exidine-2 CHG Hexirex Antiseptic Skin Cleanser Bactoshield CHG Chlorhexidine Gluconate Euro-chlorhexidine DermacinRx Surgical ComboPak Dr. Dean Stanhexidine Aqueous 2% With 4% Isopropyl Alcohol Steri-stat Liq 20% Zedoary Oils Feminine Antibacterial Gels Scrub Chlorhexidine Liq 0.05% Endure 400 Scrub-Stat 4 Soluprep AQ Applicator Soluprep AQ Wipe Hygienium KIMVENT ORAL CARE Q4 Kit WITH CHG Chlorhexseptic-liq 0.5mg/ml Stanhexidine 20% Aplicare Antiseptic Chlorhexidine Gluconate Rouhex G Liq 2% PMS-chlorhexidine Without Alcohol PS2 Aciurgy Pack Septi-san Alcohol Antibacterial Wipes Dr. Zheng s acteriostatic gel Chlorhexidine Gluconate Solution USP 20% Purell Antimicrobial Foam Scrub-stat IV 4% HYDROGEL ESSENCE Antimicrobial Virginal Gel. Stanhexidine 4% With Isopropyl Alcohol 4% Hibitane Skin Cleanser Scrub Care Soluprep Qd Solution Seaqua X Acclean Chlorhexidine Gluconate 0.12% Oral Rinse Prevantics swabstick Bactigras Soluprep Antiseptic Skin Cleanser Sponge Chlorhexidine Gluconate Solution 0.05% Baxedin 2% - 70% Bei Ling Tong Bao Er Zheng Yuan Antibacterial Creams Dyna-hex 2 Hygenipak 2% Chg Foaming Skin Cleanser Hibitane Skin Cleanser Liq 4% Endure 420 Cida-Stat Motherwort Herb Feminine Antibacterial Gels Loris I.V. Pro - Prefilled Applicator With Solution Medifresh Hand Skin Antiseptic Disinfectant Wet Wipes Dr. Luke Molluscum Wart Remover Dyural 80 LM-C Provon Antimicrobial Foam Handwash Hibistat Germicidal Hand Rinse 3M SoluPrep S Hexifoam-skin Disinfectant Aer 1% Q2 Oral Care Kit with CHG Antiseptic Skin Cleanser Hibitane Skin Cleanser 2% Dexidin 20 NuSurgePak Surgical Prep/CarePak Soluprep Swab Foam Safe X-pur Chlorhexidine Rougier Vap-chlorhexidine Gluconate 2% W/V Laura Line Chlorhexidine Antiseptic Soap Spectro Tar Antiseptic Shampoo Loris 2% Chg Body Cleanser/nettoyant Pour Le Corps Chloraprep Liq 0.5% DermacinRx Surgical PharmaPak Hexicinide Peridex Oral Rinse E-Z Scrub 107 Laura Line Antibacterial Cream Soap 2% Steri-clean 3M SoluPrep Soluprep AQ Sponge Disinfectant Fabric Wash Germi Stat Gel 4% Soft Care Antiseptic Hand Soap Ultrastat Hand Sanitizer Dexlido M-C Quick-drying rinse-free hand skin disinfectant Chlorhexidine Solution Pre-moistened Towelette Dexidin 2 Solution Periogard (Chlorhexidine Gluconate) Chloraprep Swabsticks Hibiclens Antiseptic/antimicrobial Skin Cleanser Antiseptic Cleanser Solution Bactoshield CHG Steri-stat Tincture (tinted) Antis Prep Gel Hibiclens for Georgia Pacific Maxiclens Chlorhexidine gluconate Liquid Solution, 4% Scrub, Scrub-Stat, Foam Safe, Micro-Guard ReadyPrep CHG Foaming Hand Antiseptic With Chg 2% Spectro Gram 2 Skin Cleanser Akilspray Hand Sanitizer Wart removal Anti Mucedine Feminine Wash (Qiqing) Chlorhexidine Gluconate Alcohol Disinfectant Rougier Clean Derm Sterigel Plus Antimicrobial Foam Handwash Antiseptic Cleansing Wipes Perioselect Antimicrobial Sol 0.12% Hand Sanitizer Gel Biokaab Prevantics Swabstick Foaming Chlorhexidine Gluconate Chloraprep Antiseptic Foam Handwash Dr. Luke Wart Remover Denticare Chlorhexidine Gluconate Oral Rinse 0.12% Dyna-Hex 2 BD E-Z Scrub Bactoshield Chg 2% Antiseptic Skin Cleanser Exidine-2 CHG Hand Wipes Disinfectant Wet Tissues Chlorhexidine 0.5% Liq Hibidil Baxedin Liq 20% Savlodil 3m Soluprep Sponge CliniClean ICEKING Skin Expert Refreshing Body Roller Wart Remover Ointment. Aplicare Chlorhexidine Gluconate 2% Solution Germi-stat 2% Foaming Liquid Mlk F4-C Soluprep Ld Sponge Salvesept Crm Solunet C Brosse 4% Dyna-Hex 4 Jisberry Hand Sanitizer Hand Sanitizer Biokaab Cida-stat Liq Foam Care Chg Surgical Hand Scrub CLIP Liquid Sanitizer Loris I.V. Pro - Sponge Sky Oral Rinse Scrub Care Exidine -4 CHG Steri-stat Liq 2.0% Scrub Stat 4 Foam Liq Stat Touch 2 Antimicrobial Skin Cleanser Ic-gel Ezy-TM PMS-chlorhexidine Scrub-Stat Foster and Thrive Savlon Hospital Concentrate Oro-clense Dermawerx Surgical PrePak Skinvisible Chlorhexidine Formula Hand Sanitizer Lotion Dermsafe Chlorhexidine Gluconate Hand Sanitizer Lotion Bioprep Soluprep Liquivida Hydration Dexidin 2 Detergent Scrub, Scrub-Stat NUPRO Chlorhexidine Gluconate First Aid Antiseptic Skin Cleanser Serdaen Hand wipes Dyna-hex 4 ChloraPrep Swabstick Betasept Cardinal Health Antiseptic Skin Cleanser PerioChip Hands-free skin sanitizer Soluprep Wipe Pre and Post Sx Pouch Oro Clear Rugby Antiseptic Skin Cleanser Chlorhexidine Gluconate Oral Rinse Alcohol Disinfectant Wipes Rouhex G 20% Chlorhexidine gluconate Antiseptic Body Cleanser Hibitane Skin Cleanser 4% QCare Rx Oral Cleansing and Suctioning System Cardinal Health QCare Rx Oral Cleansing and Suctioning System, Q4 Chlorhexidine Gluconante Denti-Care Denti-Rinse Chlorhexidine Gluconate Oral Rinse Spray On Plastic Bandage Aerosol Chlorhexidine Gluconate 0.12% Oral Rinse Bacti-stat Chg Disinfectant Spray(Speedy effect type) ChloraPrep One-Step Hospicare 40R Adult Body Wipes Soluprep Qd Swab Eyewash Station Additive Concentrate Germi-stat 0.5% Antiseptic Prep Gel Stanhexidine 2% With Isopropyl Alcohol 4% Sunberry Rinse free Hand Sanitizer PS1 Aciurgy Pack QCare Rx Oral Cleansing and Suctioning System, Q2 Oral Cleansing and Suctioning System, q2 Soluprep AQ Hygienipak 4% Chg Skin Cleanser Hibistat KleerSight Scrub Care Surgical Scrub Brush/nail Cleaner With Exidine 4 Baxedin Smart Sense Antiseptic Skin Cleanser Antibacterial Protective Hand Selpak Antibacterial Wet Wipes DEQGEL Advanced Hand Sanitizer Sanital Antibacterial Hand Soap 3M Avagard Cida-stat Foam Prevora Stage 1 Prevantics Maxi Swabstick Steri-stat Liq 4.0% Hygienipak 4% Chg Foaming Skin Cleanser PhysiciansCare Eyewash Station Additive Concentrate BD E-Z Scrub 107 Antimicrobial Skin Cleanser Chlorhexidine Gluconate 0.12% Oral Rinse, USP Purmist Major Oral Rinse Gelato Chlorohexidine Betalido-C Gum Paroex Avidene Surgical Scrub Kimvent Oral Care Q2 Kit with CHG Bactoshield Chg 4% Tai Yu Ling Antibacterial Sprays 10mL Antiseptic Solution Chlorhexidine-cetrimide Soltn Conc Chlorhexidine Gluconate Soluprep AQ Swab Loris 2% Chg Solution Burn O Sol Spray Loris - I.V. Soluprep Qd Wipe Soft Care 2% Chg Antimicrobial Skin Cleanser Baxedin Pre-OP Protective Hand Oris Chx Anti-bac Hand LARA MED Antibacterial Wet Wipes SAITENM Health Wet wipes B-good Hand and Skin Disinfecting Agent Chlorhexidine Gluconate, 0.12% Oral Rinse Solution Noble 75% Alcohol Wipes Freeman Packing Alcohol Wipe Soluprep Applicator Chlorhexidine 4% Antiseptic Hand Wash DermacinRx Clorhexacin Liszt Hand sanitizer without washing Zappy Ultimate Antiseptic Wipes Antiseptic Lotion Soap 2% Chlorhexidine and Isopropyl Alcohol Prep Pads Soluprep Antiseptic Skin Cleanser Preoperative Kit Stanhexidine Red Tincture 0.5% Akilgeld Hand Sanitizer Dermawerx Surgical Plus Pak Calgon Vestal 2% Chg Antimicrob.skin Cleans. Antiseptic First Aid Spray Skin antisepsis, oral cleansing, nasal antisepsis Periogard Chlorhexidine Gluconate Solution 0.75% Antiseptic JIANLIANG Antibacterial Sprays 10mL Pro-dentx Chlorhexidene Oral Rinse Peridex Oronine H Ointment 1% Skin Antisepsis, Oral Cleansing and Nasal Antisepsis System Hygenipak 2% Chg Skin Cleanser Periogard Alcohol Free Ostar Antimicrobial Hand Soap 2% - Liquid Pre-Scrub II Surgical Hand Scrub Calgon Vestal 4% Chg Antimicrob.skin Cleans. Wart Removal Pen Dyna-Hex 75 WhyteDerm SurgiPak Instillagel Loris 2% Chg Wipe/serviette Halyard Chlorhexidine Gluconate Avagard Chg Bactoshield QCare Rx Petite Oral Cleansing and Suctioning System Hibiclens SANIDEP Advanced Sanitizer with Organic Extracts Bioprep Liq Paroex Yu Ding Antibacterial Sprays 10mL Plant Herb Based Bacteriostatic Feminine Wash CleanCare Chlorhexidine Gluconate 0.12% Oral Rinse Dermsafe Pc Flamazine C Peridex Oral Rinse 0.12% Chlorhexidine Gluconate, 0.12% Oral Rinse Spray On Plastic Bandage Non-aerosol more Indication Chlorhexidine is available over-the-counter in various formulations (e.g. solution, sponge, cloth, swab) as a topical antiseptic to sanitize prior to surgeries and/or medical procedures.[L11518,L11521,L11527,L11533] Dental formulations, available by prescription only, include an oral rinse indicated for the treatment of gingivitis[L11512] and a slow-release "chip" which is inserted into periodontal pockets and is indicated for the reduction of pocket depth in adult patients with periodontitis as an adjunct therapy to dental scaling and root planing procedures.[L11536] Categories Alimentary Tract and Metabolism Amidines Anti-Infective Agents Anti-Infective Agents, Local Antiinfectives and Antiseptics for Local Oral Treatment
Antiseptics and Disinfectants Biguanides Biguanides and Amidines Compounds used in a research, industrial, or household setting Decreased Cell Wall Integrity Dental Agents Dermatologicals Disinfectants Guanidines Household Products Irrigating Solutions Medicated Dressings Medicated Dressings With Antiinfectives Miscellaneous Anti-infectives Miscellaneous Local Anti-infectives Mouthwashes Mouthwashes and Gargles Ophthalmological and Otological Preparations Ophthalmologicals Otologicals Sensory Organs Stomatological Preparations Throat Preparations more ATC-Code more CAS number 55-56-1 
