URI

URIDINE

Created:	2001-03-08
Last modified:	2011-06-04

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34 entries where URI is found as a standalone ligand1 entries where URI is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	0
Atom Count	29
Chiral Atom Count	4
Bond Count	30
Aromatic Bond Count	0

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Chemical Component Summary
Name	URIDINE
Systematic Name (OpenEye OEToolkits)	1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Formula	C₉ H₁₂ N₂ O₆
Molecular Weight	244.201
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C1NC(=O)N(C=C1)C2OC(C(O)C2O)CO
SMILES	CACTVS	3.341	OC[CH]1O[CH]([CH](O)[CH]1O)N2C=CC(=O)NC2=O
SMILES	OpenEye OEToolkits	1.5.0	C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
Canonical SMILES	CACTVS	3.341	OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
InChI	InChI	1.03	InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChIKey	InChI	1.03	DRTQHJPVMGBUCF-XVFCMESISA-N

Drug Info: DrugBank

DrugBank ID	DB02745
Name	Uridine
Groups	experimental investigational
Synonyms	Uridina Uridine
Categories	Analogs/Derivatives Nucleic Acids, Nucleotides, and Nucleosides Nucleosides Pyrimidine Analog Pyrimidine Nucleosides Pyrimidines Ribonucleosides
CAS number	58-96-8

Drug Targets

Name	Target Sequence	Pharmacological Action
U6 snRNA-associated Sm-like protein LSm6	MSLRKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEE...	unknown
Nucleoside-specific channel-forming protein tsx	MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGSYHTRFG...	unknown
Equilibrative nucleoside transporter 1	MTTSHQPQDRYKAVWLIFFMLGLGTLLPWNFFMTATQYFTNRLDMSQNVS...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682