UDP

URIDINE-5'-DIPHOSPHATE

Created:	1999-07-08
Last modified:	2024-09-27

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606 entries where UDP is found as a standalone ligand12 entries where UDP is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	0
Atom Count	39
Chiral Atom Count	4
Bond Count	40
Aromatic Bond Count	0

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Chemical Component Summary
Name	URIDINE-5'-DIPHOSPHATE
Systematic Name (OpenEye OEToolkits)	[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methyl phosphono hydrogen phosphate
Formula	C₉ H₁₄ N₂ O₁₂ P₂
Molecular Weight	404.161
Type	RNA LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	12.01	O=P(O)(O)OP(=O)(O)OCC2OC(N1C(=O)NC(=O)C=C1)C(O)C2O
SMILES	CACTVS	3.370	O[CH]1[CH](O)[CH](O[CH]1CO[P](O)(=O)O[P](O)(O)=O)N2C=CC(=O)NC2=O
SMILES	OpenEye OEToolkits	1.7.0	C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)O)O)O
Canonical SMILES	CACTVS	3.370	O[C@H]1[C@@H](O)[C@@H](O[C@@H]1CO[P](O)(=O)O[P](O)(O)=O)N2C=CC(=O)NC2=O
Canonical SMILES	OpenEye OEToolkits	1.7.0	C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO[P@@](=O)(O)OP(=O)(O)O)O)O
InChI	InChI	1.03	InChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChIKey	InChI	1.03	XCCTYIAWTASOJW-XVFCMESISA-N

Drug Info: DrugBank

DrugBank ID	DB03435
Name	Uridine-5'-Diphosphate
Groups	experimental
Description	A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety. [PubChem]
Synonyms	Uridine-5'-Diphosphate
CAS number	58-98-0

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
UDP-N-acetylglucosamine 2-epimerase	MKVLTVFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLDQVLKLF...	unknown
Histo-blood group ABO system transferase	MAEVLRTLAGKPKCHALRPMILFLIMLVLVLFGYGVLSPRSLMPGSLERG...	unknown
Galactose-1-phosphate uridylyltransferase	MTQFNPVDHPHRRYNPLTGQWILVSPHRAKRPWQGAQETPAKQVLPAHDP...	unknown
Pol polyprotein	KEFGKLEGGASCSPSESNAASSNAICTSNGGETIGFVNYNKVGTTTTLEK...	unknown
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1	MPKRRDILAIVLIVLPWTLLITVWHQSTLAPLLAVHKDEGSDPRRETPPG...	unknown
Alpha,alpha-trehalose-phosphate synthase [UDP-forming]	MSRLVVVSNRIAPPDEHAASAGGLAVGILGALKAAGGLWFGWSGETGNED...	unknown
Exostosin-like 2	MRCCHICKLPGRVMGIRVLRLSLVVILVLLLVAGALTALLPSVKEDKMLM...	unknown
Glycosyltransferase 6 domain-containing protein 1	MNSKRMLLLVLFAFSLMLVERYFRNHQVEELRLSDWFHPRKRPDVITKTD...	unknown
Spore coat polysaccharide biosynthesis protein SpsA	MPKVSVIMTSYNKSDYVAKSISSILSQTFSDFELFIMDDNSNEETLNVIR...	unknown
UMP-CMP kinase	MKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYG...	unknown
DNA beta-glucosyltransferase	MKIAIINMGNNVINFKTVPSSETIYLFKVISEMGLNVDIISLKNGVYTKS...	unknown
UDP-glucose 4-epimerase	MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGK...	unknown
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3	MKLKLKNVFLAYFLVSIAGLLYALVQLGQPCDCLPPLRAAAEQLRQKDLR...	unknown
UDP-galactose 4-epimerase	MRVLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENV...	unknown
Glycogenin-1	MTDQAFVTLTTNDAYAKGALVLGSSLKQHRTTRRLVVLATPQVSDSMRKV...	unknown
Uracil nucleotide/cysteinyl leukotriene receptor	MSKRSWWAGSRKPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQ...	unknown	regulator
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682