PUT

1,4-DIAMINOBUTANE

Created:	1999-07-08
Last modified:	2021-03-01

Find Related PDB Entry
94 entries where PUT is found as a standalone ligand3 entries where PUT is covalently linked to polymer or other heterogen groups

Help Find related ligands:
Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Help

Find related ligands:

Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Chemical Details
Formal Charge	0
Atom Count	18
Chiral Atom Count	0
Bond Count	17
Aromatic Bond Count	0

Toggle Hydrogen Toggle Labels

Chemical Component Summary
Name	1,4-DIAMINOBUTANE
Synonyms	PUTRESCINE
Systematic Name (OpenEye OEToolkits)	butane-1,4-diamine
Formula	C₄ H₁₂ N₂
Molecular Weight	88.151
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	NCCCCN
SMILES	CACTVS	3.341	NCCCCN
SMILES	OpenEye OEToolkits	1.5.0	C(CCN)CN
Canonical SMILES	CACTVS	3.341	NCCCCN
Canonical SMILES	OpenEye OEToolkits	1.5.0	C(CCN)CN
InChI	InChI	1.03	InChI=1S/C4H12N2/c5-3-1-2-4-6/h1-6H2
InChIKey	InChI	1.03	KIDHWZJUCRJVML-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB01917
Name	Putrescine
Groups	experimental
Description	Putrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. Putrescine is a solid. This compound belongs to the polyamines. These are compounds containing more than one amine group. Known drug targets of putrescine include putrescine-binding periplasmic protein, ornithine decarboxylase, and S-adenosylmethionine decarboxylase proenzyme.
Synonyms	Putrescine putrescina
Categories	Amines Biogenic Amines Biogenic Polyamines Diamines Polyamines
CAS number	110-60-1

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Beta-1 adrenergic receptor	MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESP...	unknown
Beta-2 adrenergic receptor	MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFG...	unknown
Ornithine decarboxylase	MNNFGNEEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILK...	unknown
S-adenosylmethionine decarboxylase proenzyme	MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSEWDILLKDVQCS...	unknown
Putrescine-binding periplasmic protein	MTALNKKWLSGLVAGALMAVSVGTLAAEQKTLHIYNWSDYIAPDTVANFE...	unknown
Solute carrier family 22 member 4	MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRC...	unknown	inhibitor
View More

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682