NMN

BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE

Created:	2001-01-24
Last modified:	2020-06-05

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52 entries where NMN is found as a standalone ligand1 entries where NMN is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	1
Atom Count	38
Chiral Atom Count	4
Bond Count	39
Aromatic Bond Count	6

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Chemical Component Summary
Name	BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE
Synonyms	NICOTINAMIDE MONONUCLEOTIDE
Systematic Name (OpenEye OEToolkits)	[(2R,3S,4R,5R)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate
Formula	C₁₁ H₁₆ N₂ O₈ P
Molecular Weight	335.227
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(c1ccc[n+](c1)C2OC(C(O)C2O)COP(=O)(O)O)N
SMILES	CACTVS	3.341	NC(=O)c1ccc[n+](c1)[CH]2O[CH](CO[P](O)(O)=O)[CH](O)[CH]2O
SMILES	OpenEye OEToolkits	1.5.0	c1cc(c[n+](c1)C2C(C(C(O2)COP(=O)(O)O)O)O)C(=O)N
Canonical SMILES	CACTVS	3.341	NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](CO[P](O)(O)=O)[C@@H](O)[C@H]2O
Canonical SMILES	OpenEye OEToolkits	1.5.0	c1cc(c[n+](c1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O)C(=O)N
InChI	InChI	1.03	InChI=1S/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/p+1/t7-,8-,9-,11-/m1/s1
InChIKey	InChI	1.03	DAYLJWODMCOQEW-TURQNECASA-O

Drug Info: DrugBank

DrugBank ID	DB03227
Name	Nicotinamide Mononucleotide
Groups	experimental
Description	3-Carbamoyl-1-beta-D-ribofuranosyl pyridinium hydroxide-5'phosphate, inner salt. A nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose. Synonyms: Nicotinamide Ribonucleotide; NMN. [PubChem]
Synonyms	Nicotinamide Mononucleotide
Brand Names	Lovita NMN 18000 Nmn Elitehealth Lovita NMN 38000 Reus Nr Alpha9 Ascuoli Probase Nutrition Nmn.5s Lovita NMN 12000 Nmnpqq Herodianow
Categories	Nucleic Acids, Nucleotides, and Nucleosides Nucleotides Ribonucleotides

Drug Targets

Name	Target Sequence	Pharmacological Action
ADP-ribosyl cyclase 2	MAAQGCAASRLLQLLLQLLLLLLLLAAGGARARWRGEGTSAHLRDIFLGR...	unknown
Nicotinamide mononucleotide adenylyltransferase 1	MENSEKTEVVLLACGSFNPITNMHLRLFELAKDYMNGTGRYTVVKGIISP...	unknown
Nicotinamide mononucleotide adenylyltransferase 3	MKSRIPVVLLACGSFNPITNMHLRMFEVARDHLHQTGMYQVIQGIISPVN...	unknown
DNA ligase	MEQQPLTLTAATTRAQELRKQLNQYSHEYYVKDQPSVEDYVYDRLYKELV...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682