MSE

SELENOMETHIONINE

Created:	1999-07-08
Last modified:	2024-09-27

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20 entries where MSE is found as a standalone ligand10,167 entries where MSE is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	20
Chiral Atom Count	1
Bond Count	19
Aromatic Bond Count	0

2D diagram of MSE

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Chemical Component Summary
Name	SELENOMETHIONINE
Systematic Name (OpenEye OEToolkits)	(2S)-2-amino-4-methylselanyl-butanoic acid
Formula	C₅ H₁₁ N O₂ Se
Molecular Weight	196.106
Type	L-PEPTIDE LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(O)C(N)CC[Se]C
SMILES	CACTVS	3.341	C[Se]CC[CH](N)C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	C[Se]CCC(C(=O)O)N
Canonical SMILES	CACTVS	3.341	C[Se]CC[C@H](N)C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C[Se]CC[C@@H](C(=O)O)N
InChI	InChI	1.03	InChI=1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChIKey	InChI	1.03	RJFAYQIBOAGBLC-BYPYZUCNSA-N

Drug Info: DrugBank

DrugBank ID	DB11142
Name	Selenomethionine
Groups	approved investigational
Description	Selenomethionine is a naturally occuring amino acid in some plant materials such as cereal grains, soybeans and enriched yeast but it cannot be synthesized from animals or humans. It can be produced from post-structural modifications. In vivo, selenomethionine plays an essential role in acting as an antioxidant, where it depletes reactive oxygen species (ROS) and aids in the formation and recycling of glutathione, another important antioxidant. In comparison to selenite, which is the inorganic form of selenium, the organic form of selenomethionine is more readily absorbed in the human body. Selenomethionin is used in biochemical laboratories where its incorporation into proteins that need to be visualized enhances the performance of X-ray crystallography.
Synonyms	Selenomethionine
Brand Names	RE FAC-x Viva CT Prenatal Vital-D Rx RenaPlex-D Corvite Corvite Free Bacmin
Categories	Amino Acids Amino Acids, Peptides, and Proteins Organoselenium Compounds Selenium Compounds
CAS number	3211-76-5

Related Resource References

Resource Name	Reference
PubChem	53262363, 105024
ChEMBL	CHEMBL113178
ChEBI	CHEBI:30021, CHEBI:62621
CCDC/CSD	MAJTAT

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.