MMS

MIMOSINE

Created:	2002-08-22
Last modified:	2020-06-05

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2 entries where MMS is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	24
Chiral Atom Count	1
Bond Count	24
Aromatic Bond Count	6

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Chemical Component Summary
Name	MIMOSINE
Synonyms	3-HYDROXY-4-OXO-1(4H)-PYRIDINEALANINE
Systematic Name (OpenEye OEToolkits)	(2S)-2-amino-3-(3-hydroxy-4-oxo-pyridin-1-yl)propanoic acid
Formula	C₈ H₁₀ N₂ O₄
Molecular Weight	198.176
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(O)C(N)CN1C=CC(=O)C(O)=C1
SMILES	CACTVS	3.341	N[CH](CN1C=CC(=O)C(=C1)O)C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	C1=CN(C=C(C1=O)O)CC(C(=O)O)N
Canonical SMILES	CACTVS	3.341	N[C@@H](CN1C=CC(=O)C(=C1)O)C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C1=CN(C=C(C1=O)O)C[C@@H](C(=O)O)N
InChI	InChI	1.03	InChI=1S/C8H10N2O4/c9-5(8(13)14)3-10-2-1-6(11)7(12)4-10/h1-2,4-5,12H,3,9H2,(H,13,14)/t5-/m0/s1
InChIKey	InChI	1.03	WZNJWVWKTVETCG-YFKPBYRVSA-N

Drug Info: DrugBank

DrugBank ID	DB01055
Name	Mimosine
Groups	experimental
Description	Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from _Leucena glauca_.
Synonyms	Leucaenine Leucenine (S)-2-amino-3-(3-hydroxy-4-oxo-4H-pyridin-1-yl)propanoate Leucaenol (L)-Mimosine Mimosin L-Mimosine Mimosine Leucenol
Categories	Alanine Amino Acids Amino Acids, Peptides, and Proteins Pyridines Pyridones
CAS number	500-44-7

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Serine hydroxymethyltransferase, cytosolic	MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLEL...	unknown	inhibitor
C-C motif chemokine 2	MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLAS...	unknown	inhibitor
Tyrosinase	MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLS...	unknown	inhibitor

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682