MG7

7-METHYLGUANOSINE

Created:	1999-07-08
Last modified:	2011-06-04

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4 entries where MG7 is found as a standalone ligand1 entries where MG7 is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	1
Atom Count	37
Chiral Atom Count	4
Bond Count	39
Aromatic Bond Count	5

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Chemical Component Summary
Name	7-METHYLGUANOSINE
Systematic Name (OpenEye OEToolkits)	2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-methyl-1H-purin-7-ium-6-one
Formula	C₁₁ H₁₆ N₅ O₅
Molecular Weight	298.275
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C1c2[n+](cn(c2N=C(N)N1)C3OC(C(O)C3O)CO)C
SMILES	CACTVS	3.341	C[n+]1cn([CH]2O[CH](CO)[CH](O)[CH]2O)c3N=C(N)NC(=O)c13
SMILES	OpenEye OEToolkits	1.5.0	C[n+]1cn(c2c1C(=O)NC(=N2)N)C3C(C(C(O3)CO)O)O
Canonical SMILES	CACTVS	3.341	C[n+]1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c3N=C(N)NC(=O)c13
Canonical SMILES	OpenEye OEToolkits	1.5.0	C[n+]1cn(c2c1C(=O)NC(=N2)N)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O
InChI	InChI	1.03	InChI=1S/C11H15N5O5/c1-15-3-16(8-5(15)9(20)14-11(12)13-8)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2-,12,13,14,20)/p+1/t4-,6-,7-,10-/m1/s1
InChIKey	InChI	1.03	OGHAROSJZRTIOK-KQYNXXCUSA-O

Drug Info: DrugBank

DrugBank ID	DB03493
Name	7-Methylguanosine
Groups	experimental
Synonyms	7-Methylguanosine
Categories	Heterocyclic Compounds, Fused-Ring Nucleic Acids, Nucleotides, and Nucleosides Nucleosides Purine Nucleosides Purines Ribonucleosides RNA Caps

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase	MDVVSLDKPFMYFEEIDNELDYEPESANEVAKKLPYQGQLKLLLGELFFL...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682