MED

D-METHIONINE

Created:	2002-01-18
Last modified:	2023-11-03

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6 entries where MED is found as a standalone ligand1 entries where MED is covalently linked to polymer or other heterogen groups 34 entries where MED is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	20
Chiral Atom Count	1
Bond Count	19
Aromatic Bond Count	0

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Chemical Component Summary
Name	D-METHIONINE
Systematic Name (OpenEye OEToolkits)	(2R)-2-amino-4-methylsulfanyl-butanoic acid
Formula	C₅ H₁₁ N O₂ S
Molecular Weight	149.211
Type	D-PEPTIDE LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(O)C(N)CCSC
SMILES	CACTVS	3.341	CSCC[CH](N)C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	CSCCC(C(=O)O)N
Canonical SMILES	CACTVS	3.341	CSCC[C@@H](N)C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	CSCC[C@H](C(=O)O)N
InChI	InChI	1.03	InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1
InChIKey	InChI	1.03	FFEARJCKVFRZRR-SCSAIBSYSA-N

Drug Info: DrugBank

DrugBank ID	DB02893
Name	D-Methionine
Groups	approved experimental investigational
Synonyms	D-Methionine
Brand Names	20% Prosol Nutrineal Pd4
CAS number	348-67-4

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Methionine aminopeptidase 2	MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSA...	unknown
Transcriptional regulator, HTH_3 family	MTDVMFKSQIANQLKNLRKSRGLSLDATAQLTGVSKAMLGQIERGESSPT...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
PubChem	6992109, 84815
ChEMBL	CHEMBL1234268
ChEBI	CHEBI:16867, CHEBI:57932
CCDC/CSD	URODIP03, URODIP02, VUQNAY, POVYOP, DLMETA08, DLMETA05, URODIP, FITLID, BERQIY, FAPMEP, VUQNAY01, BERNIV, FONJAU, ZATJUD, DLMETA12, ZATMOA, ZATLUF
COD	2240074, 2205625, 7212710, 2008948