Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
Lysine
(S)-α,ε-diaminocaproic acid
Lysina
(S)-lysine
Lysine monohydrate
Lysine acetate
Lysinum
L-Lysine
LYS
L-Lysin
Lysine acid
Lysine dihydrate
6-ammonio-L-norleucine
L-lys
(S)-2,6-diaminohexanoic acid
Lysine hydrochloride
L-2,6-Diaminocaproic acid
Brand Names
Novamine
Aminosyn II
Aminosyn II 5% Inj
Olimel 5.7% E
Smofkabiven
FreAmine HBC
Aminosyn RF
Smofkabiven Extra Nitrogen
Primene 10%
RenAmin
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
NephrAmine
Travasol Amino Acid Inj 5.5%
ProSol
Aminosyn Sulfite Free
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
Olimel 7.6% E
Travasol
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Aminosyn 7%
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
Travasol Amino Acid Inj 8.5%
20% Prosol
Travasol Inj Without Electrolytes 8.5%
8.5% Freamine III
Aminosyn II 7% With 10% Dextrose
Clinimix
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
Olimel 7.6%
TrophAmine
Aminosyn
FreAmine III
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
Plenamine
Primene
Aminosyn HF
Aminosyn II In Dextrose Injection
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
Aminosyn 8.5% Injection With Electrolytes
Aminosyn II with Electrolytes in Dextrose with Calcium
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
Aminosyn 10% W Electrolytes
Imubolic
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Aminosyn II 8.5% Injection
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
Aminosyn 8.5%
Smofkabiven Peripheral
Aminosyn-PF 10%
Olimel 3.3% E
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
Olimel 4.4% E
Smofkabiven Extra Nitrogen Electrolyte Free
Nephramine Liq IV
Lysakare
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
HepatAmine
Nutrineal Pd4
Synthamin
Aminosyn 3.5% M
Travasol Inj Without Electrolytes 5.5%
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
Aminosyn RF Injection
Essepna
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Primene 10%-liq IV
Aminosyn II 7% Injection
Aminosyn 5%
Renamin (amino Acids) Injection
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
Aminosyn-PF 7%
Vamin 18 Electrolyte-free
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Kabiven
Olimel 4.4%
Hepatasol
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
Smofkabiven Electrolyte Free
Perikabiven
Aminosyn II with Electrolytes
Clinisol
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
Travasol E
Effervescent Potassium Chloride
Aminosyn II 8.5% With 50% Dextrose
Premasol - sulfite-free (Amino Acid)
Aminosyn II in Dextrose
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
Olimel 5.7%
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
ProcalAmine
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
Aminosyn II 10% With Electrolytes
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Aminosyn-PF
Periolimel 2.5% E
Xyzmune
Clinimix E
Aminosyn II 7% With 50% Dextrose
Aminosyn II and Dextrose
Vamin N
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
