K1S

N,N-diethyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

Created:2018-10-25
Last modified:  2018-12-19

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Chemical Details

Formal Charge0
Atom Count30
Chiral Atom Count0
Bond Count31
Aromatic Bond Count10
2D diagram of K1S

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Chemical Component Summary

NameN,N-diethyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
Systematic Name (OpenEye OEToolkits)~{N},~{N}-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
FormulaC10 H15 N5
Molecular Weight205.26
TypeNON-POLYMER

Chemical Descriptors

TypeProgramVersionDescriptor
SMILESACDLabs12.01n1c(cc(n2ncnc12)N(CC)CC)C
SMILESCACTVS3.385CCN(CC)c1cc(C)nc2ncnn12
SMILESOpenEye OEToolkits2.0.6CCN(CC)c1cc(nc2n1ncn2)C
Canonical SMILESCACTVS3.385 CCN(CC)c1cc(C)nc2ncnn12
Canonical SMILESOpenEye OEToolkits2.0.6 CCN(CC)c1cc(nc2n1ncn2)C
InChIInChI1.03 InChI=1S/C10H15N5/c1-4-14(5-2)9-6-8(3)13-10-11-7-12-15(9)10/h6-7H,4-5H2,1-3H3
InChIKeyInChI1.03 GSNOZLZNQMLSKJ-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License
DrugBank IDDB09283 
NameTrapidil
Groups experimental
DescriptionTrapidil, a platelet-derived growth factor antagonist, was originally developed as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart, liver, and kidney disease.
SynonymsTrapidil
IndicationUsed in the treatment of chronic stable angina [A19770].
Categories
  • Antiplatelet agents
  • Cardiac Therapy
  • Cardiovascular Agents
  • Enzyme Inhibitors
  • Hematologic Agents
ATC-CodeC01DX11
CAS number15421-84-8

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License
NameTarget SequencePharmacological ActionActions
Fibroblast growth factor receptor 3MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLV...unknowninhibitor
Cyclic nucleotide phosphodiesteraseMEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSD...unknowninhibitor
Platelet-derived growth factor receptor betaMRLPGAMPALALKGELLLLSLLLLLEPQISQGLVVTPPGPELVLNVSSTF...unknownantagonist
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 5531
ChEMBL CHEMBL132767
ChEBI CHEBI:32254