GAR

GLYCINAMIDE RIBONUCLEOTIDE

Created:	1999-07-08
Last modified:	2011-06-04

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30 entries where GAR is found as a standalone ligand

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Chemical Details
Formal Charge	-2
Atom Count	31
Chiral Atom Count	4
Bond Count	31
Aromatic Bond Count	0

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Chemical Component Summary
Name	GLYCINAMIDE RIBONUCLEOTIDE
Systematic Name (OpenEye OEToolkits)	[(2R,3S,4R,5R)-5-(2-aminoethanoylamino)-3,4-dihydroxy-oxolan-2-yl]methyl phosphate
Formula	C₇ H₁₃ N₂ O₈ P
Molecular Weight	284.16
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(NC1OC(C(O)C1O)COP([O-])([O-])=O)CN
SMILES	CACTVS	3.341	NCC(=O)N[CH]1O[CH](CO[P]([O-])([O-])=O)[CH](O)[CH]1O
SMILES	OpenEye OEToolkits	1.5.0	C(C1C(C(C(O1)NC(=O)CN)O)O)OP(=O)([O-])[O-]
Canonical SMILES	CACTVS	3.341	NCC(=O)N[C@@H]1O[C@H](CO[P]([O-])([O-])=O)[C@@H](O)[C@H]1O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C([C@@H]1[C@H]([C@H]([C@@H](O1)NC(=O)CN)O)O)OP(=O)([O-])[O-]
InChI	InChI	1.03	InChI=1S/C7H15N2O8P/c8-1-4(10)9-7-6(12)5(11)3(17-7)2-16-18(13,14)15/h3,5-7,11-12H,1-2,8H2,(H,9,10)(H2,13,14,15)/p-2/t3-,5-,6-,7-/m1/s1
InChIKey	InChI	1.03	OBQMLSFOUZUIOB-SHUUEZRQSA-L

Drug Info: DrugBank

DrugBank ID	DB02236
Name	Glycinamide Ribonucleotide
Groups	experimental
Synonyms	Glycinamide Ribonucleotide
Categories	Amino Acids Amino Acids, Peptides, and Proteins Nucleic Acids, Nucleotides, and Nucleosides Nucleotides

Drug Targets

Name	Target Sequence	Pharmacological Action
Phosphoribosylglycinamide formyltransferase 2	MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAM...	unknown
Phosphoribosylglycinamide formyltransferase	MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAG...	unknown
Trifunctional purine biosynthetic protein adenosine-3	MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAI...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682