G7M

N7-METHYL-GUANOSINE-5'-MONOPHOSPHATE

Created:	1999-07-08
Last modified:	2024-09-27

Find Related PDB Entry
1 entries where G7M is found as a standalone ligand3 entries where G7M is covalently linked to polymer or other heterogen groups 403 entries where G7M is found in a polymer sequence

Help Find related ligands:
Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Help

Find related ligands:

Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Chemical Details
Formal Charge	1
Atom Count	42
Chiral Atom Count	4
Bond Count	44
Aromatic Bond Count	5

Toggle Hydrogen Toggle Labels

Chemical Component Summary
Name	N7-METHYL-GUANOSINE-5'-MONOPHOSPHATE
Systematic Name (OpenEye OEToolkits)	[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate
Formula	C₁₁ H₁₇ N₅ O₈ P
Molecular Weight	378.255
Type	RNA LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	12.01	O=P(O)(O)OCC1OC(n2c[n+](C)c3c2N=C(N)NC3=O)C(O)C1O
SMILES	CACTVS	3.385	C[n+]1cn([CH]2O[CH](CO[P](O)(O)=O)[CH](O)[CH]2O)c3N=C(N)NC(=O)c13
SMILES	OpenEye OEToolkits	2.0.7	C[n+]1cn(c2c1C(=O)NC(=N2)N)C3C(C(C(O3)COP(=O)(O)O)O)O
Canonical SMILES	CACTVS	3.385	C[n+]1cn([C@@H]2O[C@H](CO[P](O)(O)=O)[C@@H](O)[C@H]2O)c3N=C(N)NC(=O)c13
Canonical SMILES	OpenEye OEToolkits	2.0.7	C[n+]1cn(c2c1C(=O)NC(=N2)N)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O
InChI	InChI	1.06	InChI=1S/C11H16N5O8P/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(24-10)2-23-25(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H4-,12,13,14,19,20,21,22)/p+1/t4-,6-,7-,10-/m1/s1
InChIKey	InChI	1.06	AOKQNZVJJXPUQA-KQYNXXCUSA-O

Drug Info: DrugBank

DrugBank ID	DB03593
Name	7-methyl-5'-guanylic acid
Groups	experimental
Synonyms	7-methylguanosine 5'-phosphate 7-methyl-5'-guanylic acid 7-methylguanosine 5'-(dihydrogen phosphate)
Categories	Guanine Nucleotides Heterocyclic Compounds, Fused-Ring Nucleic Acids Nucleic Acids, Nucleotides, and Nucleosides Nucleotides Purine Nucleotides Purines Ribonucleotides RNA Caps RNA, Messenger

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
m7GpppX diphosphatase	MADAAPQLGKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLPFSGFRLQ...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682