FRZ

5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE

Created:	2004-07-02
Last modified:	2020-06-05

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1 entries where FRZ is found as a standalone ligand2 entries where FRZ is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	0
Atom Count	38
Chiral Atom Count	0
Bond Count	42
Aromatic Bond Count	28

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Chemical Component Summary
Name	5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE
Synonyms	FR180204
Systematic Name (OpenEye OEToolkits)	5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[5,4-c]pyridazin-3-amine
Formula	C₁₈ H₁₃ N₇
Molecular Weight	327.343
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1nc5c(cc1c3c4ccccn4nc3c2ccccc2)c(nn5)N
SMILES	CACTVS	3.341	Nc1n[nH]c2nnc(cc12)c3c4ccccn4nc3c5ccccc5
SMILES	OpenEye OEToolkits	1.5.0	c1ccc(cc1)c2c(c3ccccn3n2)c4cc5c(n[nH]c5nn4)N
Canonical SMILES	CACTVS	3.341	Nc1n[nH]c2nnc(cc12)c3c4ccccn4nc3c5ccccc5
Canonical SMILES	OpenEye OEToolkits	1.5.0	c1ccc(cc1)c2c(c3ccccn3n2)c4cc5c(n[nH]c5nn4)N
InChI	InChI	1.03	InChI=1S/C18H13N7/c19-17-12-10-13(20-22-18(12)23-21-17)15-14-8-4-5-9-25(14)24-16(15)11-6-2-1-3-7-11/h1-10H,(H3,19,21,22,23)
InChIKey	InChI	1.03	XVECMUKVOMUNLE-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB07794
Name	5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE
Groups	experimental
Synonyms	5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Mitogen-activated protein kinase 1	MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVR...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682