DST

DIMETHYLALLYL S-THIOLODIPHOSPHATE

Created:	2003-12-16
Last modified:	2020-07-15

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39 entries where DST is found as a standalone ligand2 entries where DST is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	0
Atom Count	26
Chiral Atom Count	0
Bond Count	25
Aromatic Bond Count	0

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Chemical Component Summary
Name	DIMETHYLALLYL S-THIOLODIPHOSPHATE
Synonyms	DMASPP; DMAPP; DMADP; dimethylallyl pyrophosphate; dimethylallyl diphosphate; isoprenyl pyrophosphate
Systematic Name (OpenEye OEToolkits)	3-methylbut-2-enylsulfanyl(phosphonooxy)phosphinic acid
Formula	C₅ H₁₂ O₆ P₂ S
Molecular Weight	262.158
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	12.01	OP(O)(=O)OP(O)(=O)SC\C=C(\C)C
SMILES	CACTVS	3.385	CC(C)=CCS[P](O)(=O)O[P](O)(O)=O
SMILES	OpenEye OEToolkits	2.0.7	CC(=CCSP(=O)(O)OP(=O)(O)O)C
Canonical SMILES	CACTVS	3.385	CC(C)=CCS[P](O)(=O)O[P](O)(O)=O
Canonical SMILES	OpenEye OEToolkits	2.0.7	CC(=CCS[P@@](=O)(O)OP(=O)(O)O)C
InChI	InChI	1.03	InChI=1S/C5H12O6P2S/c1-5(2)3-4-14-13(9,10)11-12(6,7)8/h3H,4H2,1-2H3,(H,9,10)(H2,6,7,8)
InChIKey	InChI	1.03	ZWFWSISPSBLNGO-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB02270
Name	Dimethylallyl S-Thiolodiphosphate
Groups	experimental
Synonyms	Dimethylallyl S-Thiolodiphosphate

Drug Targets

Name	Target Sequence	Pharmacological Action
Adenylate dimethylallyltransferase	MLLHLIYGPTCSGKTDMAIQIAQETGWPVVALDRVQCCPQIATGSGRPLE...	unknown
tRNA dimethylallyltransferase	MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSALIYKGM...	unknown
Farnesyl diphosphate synthase	MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGGKRLRPF...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682