DPR

D-PROLINE

Created:	1999-07-08
Last modified:	2023-11-03

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3 entries where DPR is found as a standalone ligand1 entries where DPR is covalently linked to polymer or other heterogen groups 215 entries where DPR is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	17
Chiral Atom Count	1
Bond Count	17
Aromatic Bond Count	0

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Chemical Component Summary
Name	D-PROLINE
Systematic Name (OpenEye OEToolkits)	(2R)-pyrrolidine-2-carboxylic acid
Formula	C₅ H₉ N O₂
Molecular Weight	115.13
Type	D-PEPTIDE LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	12.01	O=C(O)C1NCCC1
SMILES	CACTVS	3.370	OC(=O)[CH]1CCCN1
SMILES	OpenEye OEToolkits	1.7.0	C1CC(NC1)C(=O)O
Canonical SMILES	CACTVS	3.370	OC(=O)[C@H]1CCCN1
Canonical SMILES	OpenEye OEToolkits	1.7.0	C1C[C@@H](NC1)C(=O)O
InChI	InChI	1.03	InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1
InChIKey	InChI	1.03	ONIBWKKTOPOVIA-SCSAIBSYSA-N

Drug Info: DrugBank

DrugBank ID	DB02853
Name	D-Proline
Groups	experimental
Description	D-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva [A19262]. These amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity [A19263].
Synonyms	D-Proline (2R)-pyrrolidine-2-carboxylic acid DPR (R)-2-Carboxypyrrolidine (R)-pyrrolidine-2-carboxylic acid D-Prolin
CAS number	344-25-2

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Proton-coupled amino acid transporter 1	MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWF...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682