DMF

DIMETHYLFORMAMIDE

Created:	1999-07-08
Last modified:	2011-06-04

Find Related PDB Entry
52 entries where DMF is found as a standalone ligand4 entries where DMF is covalently linked to polymer or other heterogen groups

Help Find related ligands:
Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Help

Find related ligands:

Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Chemical Details
Formal Charge	0
Atom Count	12
Chiral Atom Count	0
Bond Count	11
Aromatic Bond Count	0

Toggle Hydrogen Toggle Labels

Chemical Component Summary
Name	DIMETHYLFORMAMIDE
Systematic Name (OpenEye OEToolkits)	N,N-dimethylmethanamide
Formula	C₃ H₇ N O
Molecular Weight	73.094
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=CN(C)C
SMILES	CACTVS	3.341	CN(C)C=O
SMILES	OpenEye OEToolkits	1.5.0	CN(C)C=O
Canonical SMILES	CACTVS	3.341	CN(C)C=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	CN(C)C=O
InChI	InChI	1.03	InChI=1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
InChIKey	InChI	1.03	ZMXDDKWLCZADIW-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB01844
Name	N,N-dimethylformamide
Groups	experimental
Synonyms	Dimethylformamide N,N-dimethylformamide N-Formyldimethylamine N,N-Dimethylmethanamide
Categories	Acids, Acyclic Amides Cytochrome P-450 CYP2E1 Substrates Cytochrome P-450 Substrates Formamides Formates
CAS number	68-12-2

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Chymotrypsin-like elastase family member 1	MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGG...	unknown
Renin	MDGWRRMPRWGLLLLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERG...	unknown
Cytochrome P450 2E1	MSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLEL...	unknown	substrate

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
PubChem	6228
ChEMBL	CHEMBL268291
ChEBI	CHEBI:17741
CCDC/CSD	ACEKOK, ABIWUE, ACEGOG, ADEKOJ, ACERAC, ADODUU, ADINOS, ACICOH, ADEXIR, AFUNOH, ABODIG, ADODOO, ADODII, ACEYIR, AFOGOT, ADETEL, ADADAL, ABEBIT, ABOCAW, ACOLIP, AFIWEU, AFITEP, ADEGOG, AFETOU, ABUHOY, ABIGEB, ABEXAK, ABEXUE
COD	7203856, 2216716, 7211800