CGU

GAMMA-CARBOXY-GLUTAMIC ACID

Created:	1999-07-08
Last modified:	2024-09-27

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84 entries where CGU is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	22
Chiral Atom Count	1
Bond Count	21
Aromatic Bond Count	0

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Chemical Component Summary
Name	GAMMA-CARBOXY-GLUTAMIC ACID
Systematic Name (OpenEye OEToolkits)	(3S)-3-aminopropane-1,1,3-tricarboxylic acid
Formula	C₆ H₉ N O₆
Molecular Weight	191.139
Type	L-PEPTIDE LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(O)C(C(=O)O)CC(N)C(=O)O
SMILES	CACTVS	3.341	N[CH](CC(C(O)=O)C(O)=O)C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	C(C(C(=O)O)C(=O)O)C(C(=O)O)N
Canonical SMILES	CACTVS	3.341	N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C(C(C(=O)O)C(=O)O)[C@@H](C(=O)O)N
InChI	InChI	1.03	InChI=1S/C6H9NO6/c7-3(6(12)13)1-2(4(8)9)5(10)11/h2-3H,1,7H2,(H,8,9)(H,10,11)(H,12,13)/t3-/m0/s1
InChIKey	InChI	1.03	UHBYWPGGCSDKFX-VKHMYHEASA-N

Drug Info: DrugBank

DrugBank ID	DB03847
Name	gamma-carboxy-L-glutamic acid
Groups	experimental
Synonyms	(3S)-3-amino-1,1,3-propanetricarboxylic acid gamma-Carboxyglutamic acid gamma-carboxy-glutamic acid γ-carboxy-L-glutamic acid gamma-carboxy-L-glutamic acid
Categories	1-Carboxyglutamic Acid Acids, Acyclic Amino Acids Amino Acids, Acidic Amino Acids, Dicarboxylic Amino Acids, Peptides, and Proteins Glutamates Tricarboxylic Acids
CAS number	53861-57-7

Drug Targets

Name	Target Sequence	Pharmacological Action
Prothrombin	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEE...	unknown
Osteocalcin	MRALTLLALLALAALCIAGQAGAKPSGAESSKGAAFVSKQEGSEVVKRPR...	unknown
Coagulation factor X	MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKK...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682