CAM
CAMPHOR
Created: | 1999-07-08 |
Last modified: | 2011-06-04 |
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Chemical Details | |
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Formal Charge | 0 |
Atom Count | 27 |
Chiral Atom Count | 2 |
Bond Count | 28 |
Aromatic Bond Count | 0 |
Chemical Component Summary | |
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Name | CAMPHOR |
Systematic Name (OpenEye OEToolkits) | (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-6-one |
Formula | C10 H16 O |
Molecular Weight | 152.233 |
Type | NON-POLYMER |
Chemical Descriptors | |||
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Type | Program | Version | Descriptor |
SMILES | ACDLabs | 10.04 | O=C1CC2CCC1(C)C2(C)C |
SMILES | CACTVS | 3.341 | CC1(C)[CH]2CC[C]1(C)C(=O)C2 |
SMILES | OpenEye OEToolkits | 1.5.0 | CC1(C2CCC1(C(=O)C2)C)C |
Canonical SMILES | CACTVS | 3.341 | CC1(C)[C@@H]2CC[C@@]1(C)C(=O)C2 |
Canonical SMILES | OpenEye OEToolkits | 1.5.0 | CC1([C@@H]2CC[C@]1(C(=O)C2)C)C |
InChI | InChI | 1.03 | InChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m1/s1 |
InChIKey | InChI | 1.03 | DSSYKIVIOFKYAU-XCBNKYQSSA-N |
Drug Info: DrugBank
DrugBank ID | DB01744 |
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Name | Camphor |
Groups |
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Description | Camphor is a bicyclic monoterpene ketone found widely in plants, especially _Cinnamomum camphora_. It is used topically as a skin antipruritic and as an anti-infective agent. When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often responsible for its toxicity. The FDA ruled that camphorated oil could not be marketed in the United States and that no product could contain a concentration higher than 11%. It appears in the list of drug products withdrawn or removed from the market for safety or effectiveness.[A254252,L43942] However, camphor can be found in several nonprescription medications at lower concentrations.[A254252] |
Synonyms |
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Brand Names |
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Categories |
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ATC-Code | C01EB02 |
CAS number | 464-49-3 |
Drug Targets
Name | Target Sequence | Pharmacological Action | Actions |
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Transient receptor potential cation channel subfamily V member 1 | MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLF... | unknown | agonist,activator |
Transient receptor potential cation channel subfamily V member 3 | MKAHPKEMVPLMGKRVAAPSGNPAILPEKRPAEITPTKKSAHFFLEIEGF... | unknown | agonist,activator |
Transient receptor potential cation channel subfamily A member 1 | MKRSLRKMWRPGEKKEPQGVVYEDVPDDTEDFKESLKVVFEGSAYGLQNF... | unknown | inhibitor |
Transient receptor potential cation channel subfamily M member 8 | MSFRAARLSMRNRRNDTLDSTRTLYSSASRSTDLSYSESDLVNFIQANFK... | unknown | activator |
Camphor 5-monooxygenase | MTTETIQSNANLAPLPPHVPEHLVFDFDMYNPSNLSAGVQEAWAVLQESN... | unknown | substrate |
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
Resource Name | Reference |
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PubChem | 159055 |
ChEMBL | CHEMBL504760 |
ChEBI | CHEBI:15396 |
CCDC/CSD | UGAHUF, PAMFOB |