BZM

BENZOIC ACID PHENYLMETHYLESTER

Created:	2000-03-06
Last modified:	2011-06-04

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2 entries where BZM is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	28
Chiral Atom Count	0
Bond Count	29
Aromatic Bond Count	12

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Chemical Component Summary
Name	BENZOIC ACID PHENYLMETHYLESTER
Systematic Name (OpenEye OEToolkits)	phenylmethyl benzoate
Formula	C₁₄ H₁₂ O₂
Molecular Weight	212.244
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(OCc1ccccc1)c2ccccc2
SMILES	CACTVS	3.341	O=C(OCc1ccccc1)c2ccccc2
SMILES	OpenEye OEToolkits	1.5.0	c1ccc(cc1)COC(=O)c2ccccc2
Canonical SMILES	CACTVS	3.341	O=C(OCc1ccccc1)c2ccccc2
Canonical SMILES	OpenEye OEToolkits	1.5.0	c1ccc(cc1)COC(=O)c2ccccc2
InChI	InChI	1.03	InChI=1S/C14H12O2/c15-14(13-9-5-2-6-10-13)16-11-12-7-3-1-4-8-12/h1-10H,11H2
InChIKey	InChI	1.03	SESFRYSPDFLNCH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB00676
Name	Benzyl benzoate
Groups	approved
Description	Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. It is also used to treat lice infestation of the head and body. Benzyl benzoate is not the treatment of choice for scabies due to its irritant properties.
Synonyms	Acarobenzyl Benzoic acid phenylmethylester Benzoesäurebenzylester Benzoate de benzyle Benzevan Benzyl benzoat Benzoic acid, phenylmethyl ester Phenylmethyl benzoate Benzoic acid, benzyl ester Benzylis benzoas Benzyl benzoate Benylate
Indication	Used to kill lice and the mites responsible for the skin condition scabies.
Categories	Acaricides Acids, Carbocyclic Agrochemicals Antiparasitic Products, Insecticides and Repellents Benzene Derivatives Compounds used in a research, industrial, or household setting Ectoparasiticides, Incl. Scabicides Ectoparasiticides, Incl. Scabicides, Insecticides and Repellents Insecticides Pesticides Toxic Actions
ATC-Code	P03AX01
CAS number	120-51-4

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Hormone-sensitive lipase	MEPGSKSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQK...	unknown	modulator

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682