AME

N-ACETYLMETHIONINE

Created:	2000-05-11
Last modified:	2024-09-27

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8 entries where AME is found as a standalone ligand97 entries where AME is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	25
Chiral Atom Count	1
Bond Count	24
Aromatic Bond Count	0

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Chemical Component Summary
Name	N-ACETYLMETHIONINE
Systematic Name (OpenEye OEToolkits)	(2S)-2-acetamido-4-methylsulfanyl-butanoic acid
Formula	C₇ H₁₃ N O₃ S
Molecular Weight	191.248
Type	L-PEPTIDE NH3 AMINO TERMINUS

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(NC(C(=O)O)CCSC)C
SMILES	CACTVS	3.341	CSCC[CH](NC(C)=O)C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	CC(=O)NC(CCSC)C(=O)O
Canonical SMILES	CACTVS	3.341	CSCC[C@H](NC(C)=O)C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	CC(=O)N[C@@H](CCSC)C(=O)O
InChI	InChI	1.03	InChI=1S/C7H13NO3S/c1-5(9)8-6(7(10)11)3-4-12-2/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)/t6-/m0/s1
InChIKey	InChI	1.03	XUYPXLNMDZIRQH-LURJTMIESA-N

Drug Info: DrugBank

DrugBank ID	DB01646
Name	N-Acetylmethionine
Groups	experimental
Synonyms	Methionamine Nα-acetyl-L-methionine Acetyl-L-methionine L-(N-Acetyl)methionine N-Ac-Met Acetylmethionine Thiomedon AcMet (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid Methionin N-Acetylmethionine N-acetyl-L-methionine
Categories	Amino Acids Amino Acids, Neutral Amino Acids, Peptides, and Proteins Amino Acids, Sulfur Sulfur Compounds
CAS number	65-82-7

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Rhodopsin	MNGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVL...	unknown
N-acylamino acid racemase	MKLSGVELRRVQMPLVAPFRTSFGTQSVRELLLLRAVTPAGEGWGECVTM...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682