141

Oxypurinol

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is present as a standalone ligand in 5 entries

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Chemical Component Summary
Name	Oxypurinol
Synonyms	Alloxanthine
Identifiers	1,2-dihydropyrazolo[3,4-d]pyrimidine-4,6-dione
Formula	C₅ H₄ N₄ O₂
Molecular Weight	152.111
Type	NON-POLYMER
Isomeric SMILES	C1=C2C(=NC(=O)NC2=O)NN1
InChI	InChI=1S/C5H4N4O2/c10-4-2-1-6-9-3(2)7-5(11)8-4/h1H,(H3,6,7,8,9,10,11)
InChIKey	HXNFUBHNUDHIGC-UHFFFAOYSA-N

Chemical Details
Formal Charge	0
Atom Count	15
Chiral Atom Count	0
Bond Count	16
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB05262
Name	Oxypurinol
Groups	investigational
Description	Oxypurinol, an inhibitor of xanthine oxidase, is a metabolite of allopurinol.
Synonyms	Oxoallopurinol 1H-Pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione Oxipurinolum DHPP Oxipurinol Oxypurinol Alloxanthine Ossipurinolo
Indication	Intended for the treatment of congestive heart failure and hyperuricemia.
Categories	Enzyme Inhibitors Pyrazoles Pyrimidines Xanthine Oxidase Inhibitors
CAS number	2465-59-0

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Xanthine dehydrogenase/oxidase	MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGA...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682