Crystal Structure of Bovine Enterovirus 2 determined with Serial Femtosecond X-ray Crystallography
Serial Crystallography (SX)
Starting Model(s)
Initial Refinement Model(s) |
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Type | Source | Accession Code | Details |
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experimental model | PDB | 1BEV | |
Crystallization
Crystalization Experiments |
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ID | Method | pH | Temperature | Details |
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1 | VAPOR DIFFUSION, SITTING DROP | 8.5 | 293 | 1.500 M Ammonium Sulphate 0.100 M Tris |
Crystal Data
Unit Cell |
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Length ( Å ) | Angle ( ˚ ) |
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a = 436.6 | α = 90 |
b = 436.6 | β = 90 |
c = 436.6 | γ = 90 |
Diffraction
Diffraction Experiment |
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ID # | Crystal ID | Scattering Type | Data Collection Temperature | Detector | Detector Type | Details | Collection Date | Monochromator | Protocol |
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1 | 1 | x-ray | 293 | PIXEL | CS-PAD XPP | | 2015-07-22 | M | SINGLE WAVELENGTH |
Radiation Source |
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ID # | Source | Type | Wavelength List | Synchrotron Site | Beamline |
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1 | FREE ELECTRON LASER | SLAC LCLS BEAMLINE XPP | 1.305 | SLAC LCLS | XPP |
Data Collection
Overall |
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ID # | Resolution (High) | Resolution (Low) | Percent Possible (Observed) | CC (Half) | R Split (All) | Net I Over Average Sigma (I) | Redundancy | Number Reflections (All) | Number Reflections (Observed) | Observed Criterion Sigma (F) | Observed Criterion Sigma (I) | B (Isotropic) From Wilson Plot |
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1 | 2.3 | 30 | 82.1 | 0.746 | 0.486 | 5.4 | 2.3 | | 235593 | | | 36.6 |
Highest Resolution Shell |
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ID # | Resolution (High) | Resolution (Low) | Percent Possible (All) | Percent Possible (Observed) | Mean I Over Sigma (Observed) | Redundancy | Number Unique Reflections (All) |
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1 | 2.3 | 2.37 | 83.6 | | | 2.4 | |
Refinement
Statistics |
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Diffraction ID | Structure Solution Method | Cross Validation method | Starting model | Resolution (High) | Resolution (Low) | Number Reflections (Observed) | Number Reflections (R-Free) | Percent Reflections (Observed) | R-Factor (Observed) | R-Work | R-Free | R-Free Selection Details | Mean Isotropic B |
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X-RAY DIFFRACTION | MOLECULAR REPLACEMENT | THROUGHOUT | 1BEV | 2.3 | 29.71 | 235593 | 11604 | 78 | 0.233 | 0.233 | 0.257 | RANDOM | 32.1 |
Temperature Factor Modeling |
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Anisotropic B[1][1] | Anisotropic B[1][2] | Anisotropic B[1][3] | Anisotropic B[2][2] | Anisotropic B[2][3] | Anisotropic B[3][3] |
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| | | | | |
RMS Deviations |
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Key | Refinement Restraint Deviation |
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c_dihedral_angle_d | 26.3 |
c_scangle_it | 15.5 |
c_scbond_it | 13.97 |
c_mcangle_it | 11.32 |
c_mcbond_it | 10.92 |
c_angle_deg | 1.6 |
c_improper_angle_d | 1.07 |
c_bond_d | 0.011 |
c_bond_d_na | |
c_bond_d_prot | |
RMS Deviations |
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Key | Refinement Restraint Deviation |
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c_dihedral_angle_d | 26.3 |
c_scangle_it | 15.5 |
c_scbond_it | 13.97 |
c_mcangle_it | 11.32 |
c_mcbond_it | 10.92 |
c_angle_deg | 1.6 |
c_improper_angle_d | 1.07 |
c_bond_d | 0.011 |
c_bond_d_na | |
c_bond_d_prot | |
c_angle_d | |
c_angle_d_na | |
c_angle_d_prot | |
c_angle_deg_na | |
c_angle_deg_prot | |
c_dihedral_angle_d_na | |
c_dihedral_angle_d_prot | |
c_improper_angle_d_na | |
c_improper_angle_d_prot | |
Non-Hydrogen Atoms Used in Refinement |
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Non-Hydrogen Atoms | Number |
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Protein Atoms | 6202 |
Nucleic Acid Atoms | |
Solvent Atoms | 341 |
Heterogen Atoms | 49 |
Software
Software |
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Software Name | Purpose |
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CNS | refinement |
CNS | phasing |