Annotations: 9C4B

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Actin-like protein 6A	chromatin binding binding transcription coactivator activity transcription regulator activity transcription coregulator activity protein-macromolecule adaptor activity molecular adaptor activity	regulation of chromosome segregation regulation of cell cycle phase transition regulation of cellular process regulation of metaphase/anaphase transition of cell cycle regulation of cellular component organization cell cycle phase transition regulation of mitotic metaphase/anaphase transition mitotic cell cycle cellular component organization regulation of mitotic cell cycle cell cycle cellular component organization or biogenesis regulation of cell cycle chromosome segregation regulation of chromosome segregation regulation of cell cycle phase transition regulation of cellular process regulation of metaphase/anaphase transition of cell cycle regulation of cellular component organization cell cycle phase transition regulation of mitotic metaphase/anaphase transition mitotic cell cycle cellular component organization regulation of mitotic cell cycle cell cycle cellular component organization or biogenesis regulation of cell cycle chromosome segregation cell cycle process regulation of biological process regulation of cell cycle process biological regulation chromosome organization sister chromatid segregation regulation of chromosome organization regulation of organelle organization regulation of mitotic cell cycle phase transition organelle organization mitotic cell cycle process regulation of sister chromatid segregation nuclear chromosome segregation metaphase/anaphase transition of mitotic cell cycle cellular process metaphase/anaphase transition of cell cycle mitotic cell cycle phase transition developmental process regulation of developmental process cellular developmental process positive regulation of biological process regulation of cell differentiation positive regulation of myoblast differentiation muscle structure development positive regulation of developmental process positive regulation of cell differentiation cell differentiation anatomical structure development regulation of myoblast differentiation myoblast differentiation positive regulation of cellular process primary metabolic process DNA metabolic process regulation of macromolecule metabolic process nucleic acid metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process DNA replication metabolic process macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of metabolic process regulation of DNA replication regulation of DNA metabolic process regulation of apoptotic process apoptotic process regulation of programmed cell death cell death programmed cell death cellular response to stimulus response to stimulus regulation of cellular response to stress positive regulation of response to stimulus positive regulation of metabolic process positive regulation of DNA repair cellular response to stress response to stress regulation of response to stress positive regulation of macromolecule metabolic process DNA repair positive regulation of nucleobase-containing compound metabolic process regulation of DNA repair positive regulation of DNA metabolic process regulation of response to stimulus DNA damage response regulation of DNA recombination regulation of double-strand break repair positive regulation of double-strand break repair via homologous recombination recombinational repair double-strand break repair via homologous recombination positive regulation of DNA recombination double-strand break repair DNA recombination positive regulation of double-strand break repair regulation of double-strand break repair via homologous recombination RNA metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process regulation of gene expression biosynthetic process regulation of macromolecule biosynthetic process regulation of DNA-templated transcription multicellular organism development multicellular organismal process nervous system development system development negative regulation of developmental process negative regulation of biological process negative regulation of cellular process negative regulation of cell differentiation positive regulation of organelle organization telomere maintenance in response to DNA damage telomere organization positive regulation of telomere maintenance positive regulation of chromosome organization telomere maintenance regulation of telomere maintenance positive regulation of cellular component organization positive regulation of telomere maintenance in response to DNA damage regulation of telomere maintenance in response to DNA damage sensory organ development eye development animal organ development retina development in camera-type eye visual system development neural retina development camera-type eye development sensory system development chordate embryonic development embryo development in utero embryonic development anatomical structure morphogenesis blastocyst formation embryo development ending in birth or egg hatching anatomical structure formation involved in morphogenesis blastocyst development spinal cord development central nervous system development regulation of stem cell population maintenance stem cell population maintenance positive regulation of stem cell population maintenance positive regulation of multicellular organismal process regulation of multicellular organismal process maintenance of cell number signaling signal transduction cell communication cell population proliferation positive regulation of cell population proliferation regulation of cell population proliferation nucleotide-excision repair regulation of nucleotide-excision repair positive regulation of DNA-templated transcription positive regulation of macromolecule biosynthetic process positive regulation of biosynthetic process positive regulation of RNA metabolic process positive regulation of RNA biosynthetic process regulation of G0 to G1 transition G0 to G1 transition regulation of embryonic development regulation of multicellular organismal development transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of cell cycle G1/S phase transition cell cycle G1/S phase transition regulation of G1/S transition of mitotic cell cycle G1/S transition of mitotic cell cycle regulation of DNA strand elongation DNA strand elongation regulation of leukocyte differentiation regulation of leukocyte activation regulation of cell activation mononuclear cell differentiation lymphocyte differentiation positive regulation of T cell differentiation regulation of cell development positive regulation of cell activation T cell activation positive regulation of leukocyte activation T cell differentiation regulation of immune system process positive regulation of immune system process positive regulation of T cell activation positive regulation of cell development regulation of leukocyte cell-cell adhesion leukocyte differentiation cell development positive regulation of leukocyte cell-cell adhesion lymphocyte activation leukocyte cell-cell adhesion leukocyte activation positive regulation of cell-cell adhesion regulation of T cell differentiation positive regulation of lymphocyte activation cell adhesion cell-cell adhesion positive regulation of hemopoiesis regulation of cell-cell adhesion regulation of lymphocyte differentiation hemopoiesis positive regulation of cell adhesion regulation of cell adhesion cell activation regulation of T cell activation immune system process regulation of hemopoiesis positive regulation of leukocyte differentiation positive regulation of lymphocyte differentiation regulation of lymphocyte activation chromatin organization chromatin remodeling	membrane-bounded organelle ATPase complex protein-containing complex intracellular anatomical structure nucleus membrane-enclosed lumen nuclear protein-containing complex nuclear chromosome chromosome intracellular organelle lumen intracellular organelle cellular anatomical structure membraneless organelle SWI/SNF superfamily-type complex membrane-bounded organelle ATPase complex protein-containing complex intracellular anatomical structure nucleus membrane-enclosed lumen nuclear protein-containing complex nuclear chromosome chromosome intracellular organelle lumen intracellular organelle cellular anatomical structure membraneless organelle SWI/SNF superfamily-type complex INO80-type complex catalytic complex intracellular membraneless organelle chromatin intracellular membrane-bounded organelle Ino80 complex organelle lumen organelle nuclear lumen brahma complex GBAF complex SWI/SNF complex npBAF complex nuclear periphery nuclear matrix NuA4 histone acetyltransferase complex transferase complex H4/H2A histone acetyltransferase complex histone acetyltransferase complex acetyltransferase complex H4 histone acetyltransferase complex protein acetyltransferase complex intracellular protein-containing complex RSC-type complex cell periphery plasma membrane membrane protein-DNA complex nucleosome nucleoplasm chromosomal region kinetochore chromosome, centromeric region condensed chromosome, centromeric region supramolecular complex condensed chromosome

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR004001	Actin, conserved site	Conserved Site
A	IPR043129	ATPase, nucleotide binding domain	Homologous Superfamily
A	IPR004000	Actin family	Family

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A	Pharos: O96019	pilocytic astrocytoma acute myeloid leukemia breast cancer glioblastoma large cell medulloblastoma malignant ependymoma medulloblastoma osteosarcoma primitive neuroectodermal tumor astrocytic tumor gastric cancer hepatocellular carcinoma lung adenocarcinoma malignant glioma non-small cell lung carcinoma pilocytic astrocytoma acute myeloid leukemia breast cancer glioblastoma large cell medulloblastoma malignant ependymoma medulloblastoma osteosarcoma primitive neuroectodermal tumor astrocytic tumor gastric cancer hepatocellular carcinoma lung adenocarcinoma malignant glioma non-small cell lung carcinoma ovarian cancer psoriasis atypical teratoid rhabdoid tumor gastric carcinoma intellectual disability lung cancer malignant mesothelioma oligodendroglioma

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.