Annotations: 8TF5

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF07361	Cytochrome b562 (Cytochrom_B562)	Cytochrome b562	-	Family
A	PF00001	7 transmembrane receptor (rhodopsin family) (7tm_1)	7 transmembrane receptor (rhodopsin family)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	G-protein coupled receptor 6,Soluble cytochrome b562 chimera,Soluble cytochrome b562,G-protein coupled receptor 6	bioactive lipid receptor activity sphingosine-1-phosphate receptor activity molecular transducer activity G protein-coupled receptor activity transmembrane signaling receptor activity signaling receptor activity binding organic cyclic compound binding tetrapyrrole binding heme binding electron transfer activity cation binding transition metal ion binding iron ion binding bioactive lipid receptor activity sphingosine-1-phosphate receptor activity molecular transducer activity G protein-coupled receptor activity transmembrane signaling receptor activity signaling receptor activity binding organic cyclic compound binding tetrapyrrole binding heme binding electron transfer activity cation binding transition metal ion binding iron ion binding ion binding metal ion binding small molecule binding	cellular response to stimulus regulation of biological process regulation of cellular process response to stimulus signaling biological regulation adenylate cyclase-activating G protein-coupled receptor signaling pathway cell communication adenylate cyclase-modulating G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway cellular process signal transduction metabolic process regulation of metabolic process cellular response to stimulus regulation of biological process regulation of cellular process response to stimulus signaling biological regulation adenylate cyclase-activating G protein-coupled receptor signaling pathway cell communication adenylate cyclase-modulating G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway cellular process signal transduction metabolic process regulation of metabolic process positive regulation of cytosolic calcium ion concentration regulation of biological quality electron transport chain generation of precursor metabolites and energy	cell periphery cellular anatomical structure plasma membrane membrane intracellular anatomical structure cytoplasm periplasmic space

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR000276	G protein-coupled receptor, rhodopsin-like	Family
A	IPR001151	G protein-coupled receptor 6	Family
A	IPR017452	GPCR, rhodopsin-like, 7TM	Domain
A	IPR000723	G protein-coupled receptor 3/6/12 orphan	Family
A	IPR010980	Cytochrome c/b562	Homologous Superfamily
A	IPR009155	Cytochrome b562	Family

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A	Pharos: P46095	astrocytic tumor malignant ependymoma oligodendroglioma pituitary cancer atypical teratoid rhabdoid tumor malignant glioma osteosarcoma primitive neuroectodermal tumor glioblastoma medulloblastoma pilocytic astrocytoma

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A	PDBTM	Annotated as membrane protein by PDBTM

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.