8J4X

Structure of Mycobacterium tuberculosis NrdF2:NrdIcomplex (oxidised) determined at 3 angstrom resolution

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C	SCOP2B Superfamily	Ferritin-like	8041035	3001658	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Ferritin-like	8041035	3001658	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Ferritin-like	8041035	3001658	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Ferritin-like	8041035	3001658	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Ferritin-like	8041035	3001658	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Ferritin-like	8041035	3001658	SCOP2B (2022-06-29)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF00268	Ribonucleotide reductase, small chain (Ribonuc_red_sm)	Ribonucleotide reductase, small chain	-	Domain
G, H [auth I]	PF07972	NrdI Flavodoxin like (Flavodoxin_NdrI)	NrdI Flavodoxin like	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	Ribonucleoside-diphosphate reductase subunit beta nrdF2	ribonucleoside-diphosphate reductase activity oxidoreductase activity oxidoreductase activity, acting on CH or CH2 groups oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor catalytic activity cation binding ion binding binding metal ion binding small molecule binding	nucleobase-containing compound metabolic process DNA replication metabolic process cellular process primary metabolic process DNA metabolic process macromolecule metabolic process nucleic acid metabolic process nucleoside phosphate metabolic process carbohydrate derivative biosynthetic process nucleotide biosynthetic process carbohydrate derivative metabolic process nucleotide metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process DNA replication metabolic process cellular process primary metabolic process DNA metabolic process macromolecule metabolic process nucleic acid metabolic process nucleoside phosphate metabolic process carbohydrate derivative biosynthetic process nucleotide biosynthetic process carbohydrate derivative metabolic process nucleotide metabolic process nucleobase-containing compound biosynthetic process deoxyribonucleotide biosynthetic process deoxyribonucleotide metabolic process biosynthetic process organophosphate metabolic process nucleobase-containing small molecule metabolic process organophosphate biosynthetic process phosphate-containing compound metabolic process nucleoside phosphate biosynthetic process small molecule metabolic process phosphorus metabolic process	protein-containing complex cellular anatomical structure intracellular anatomical structure catalytic complex oxidoreductase complex cytoplasm cytosol ribonucleoside-diphosphate reductase complex
G, H [auth I]	Protein NrdI	binding nucleotide binding FMN binding nucleoside phosphate binding ion binding organic cyclic compound binding anion binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding	macromolecule modification metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process protein modification process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR009078	Ferritin-like superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR026494	Ribonucleoside-diphosphate reductase subunit beta	Family
A, B, C, D, E A, B, C, D, E, F	IPR000358	Ribonucleotide reductase small subunit family	Family
A, B, C, D, E A, B, C, D, E, F	IPR030475	Ribonucleotide reductase small subunit, acitve site	Active Site
A, B, C, D, E A, B, C, D, E, F	IPR033909	Ribonucleotide reductase small subunit	Family
A, B, C, D, E A, B, C, D, E, F	IPR012348	Ribonucleotide reductase-like	Homologous Superfamily
G, H [auth I]	IPR029039	Flavoprotein-like superfamily	Homologous Superfamily
G, H [auth I]	IPR004465	Ribonucleotide reductase Class Ib, NrdI	Family
G, H [auth I]	IPR020852	Ribonucleotide reductase, class Ib, NrdI, bacterial	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.