Annotations: 7RE4

Chains	Accession	Name	Description	Comments	Source
A, B [auth C], C [auth E]	PF22829	HphA C-terminal domain (HphA_C)	HphA C-terminal domain	HphA is a secreted hemophore that binds and acquires heme from hemoglobin. It consists of two domains: N-terminal heme binding domain and C-terminal beta-barrel (this entry) that is related to domains members of the Outer membrane beta-barrel superfa ...	HphA is a secreted hemophore that binds and acquires heme from hemoglobin. It consists of two domains: N-terminal heme binding domain and C-terminal beta-barrel (this entry) that is related to domains members of the Outer membrane beta-barrel superfamily [1].	Domain
A, B [auth C], C [auth E]	PF22828	HphA N-terminal heme-binding domain (HphA_N)	HphA N-terminal heme-binding domain	HphA is a secreted hemophore that binds and acquires heme from hemoglobin. It consists of two domains: N-terminal heme binding domain (this entry) and C-terminal beta-barrel that is related to domains members of the Outer membrane beta-barrel superfa ...	HphA is a secreted hemophore that binds and acquires heme from hemoglobin. It consists of two domains: N-terminal heme binding domain (this entry) and C-terminal beta-barrel that is related to domains members of the Outer membrane beta-barrel superfamily. The N-terminal domain has a clamp-like structure consisting of six antiparallel beta-strands and an alpha-helix. Two histidines located on loops coordinate the heme [1].	Domain

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B [auth C], C [auth E]	Hemophilin	cation binding ion binding binding metal ion binding small molecule binding	-	cellular anatomical structure extracellular region

Chains	Accession	Name	Type
A, B [auth C], C [auth E]	IPR011250	Outer membrane protein/outer membrane enzyme PagP, beta-barrel	Homologous Superfamily
A, B [auth C], C [auth E]	IPR054843	Slam-dependent hemophilin, C-terminal domain	Domain
A, B [auth C], C [auth E]	IPR054535	HphA, N-terminal heme-binding domain	Domain
A, B [auth C], C [auth E]	IPR054536	HphA, C-terminal domain	Domain