7P5O

Crystal structure of Aspergillus fumigatus phosphoglucomutase in complex with the reaction intermediate

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	PGM_PMM_IV_1	e7p5oB4	A: a+b two layers	X: TBP-like	H: Phosphoglucomutase, C-terminal domain (From Topology)	T: Phosphoglucomutase, C-terminal domain	F: PGM_PMM_IV_1	ECOD (1.6)
B	PGM_PMM_I	e7p5oB3	A: a/b three-layered sandwiches	X: Phosphoglucomutase, first 3 domains (From Topology)	H: Phosphoglucomutase, first 3 domains (From Topology)	T: Phosphoglucomutase, first 3 domains	F: PGM_PMM_I	ECOD (1.6)
B	PGM_PMM_II	e7p5oB1	A: a/b three-layered sandwiches	X: Phosphoglucomutase, first 3 domains (From Topology)	H: Phosphoglucomutase, first 3 domains (From Topology)	T: Phosphoglucomutase, first 3 domains	F: PGM_PMM_II	ECOD (1.6)
B	PGM_PMM_III_1	e7p5oB2	A: a/b three-layered sandwiches	X: Phosphoglucomutase, first 3 domains (From Topology)	H: Phosphoglucomutase, first 3 domains (From Topology)	T: Phosphoglucomutase, first 3 domains	F: PGM_PMM_III_1	ECOD (1.6)
A	PGM_PMM_IV_1	e7p5oA3	A: a+b two layers	X: TBP-like	H: Phosphoglucomutase, C-terminal domain (From Topology)	T: Phosphoglucomutase, C-terminal domain	F: PGM_PMM_IV_1	ECOD (1.6)
A	PGM_PMM_I	e7p5oA4	A: a/b three-layered sandwiches	X: Phosphoglucomutase, first 3 domains (From Topology)	H: Phosphoglucomutase, first 3 domains (From Topology)	T: Phosphoglucomutase, first 3 domains	F: PGM_PMM_I	ECOD (1.6)
A	PGM_PMM_II	e7p5oA1	A: a/b three-layered sandwiches	X: Phosphoglucomutase, first 3 domains (From Topology)	H: Phosphoglucomutase, first 3 domains (From Topology)	T: Phosphoglucomutase, first 3 domains	F: PGM_PMM_II	ECOD (1.6)
A	PGM_PMM_III_1	e7p5oA2	A: a/b three-layered sandwiches	X: Phosphoglucomutase, first 3 domains (From Topology)	H: Phosphoglucomutase, first 3 domains (From Topology)	T: Phosphoglucomutase, first 3 domains	F: PGM_PMM_III_1	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF02878	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I (PGM_PMM_I)	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I	-	Domain
A, B	PF02879	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II (PGM_PMM_II)	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II	-	Domain
A, B	PF02880	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III (PGM_PMM_III)	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Phosphoglucomutase	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding phosphoglucomutase activity isomerase activity intramolecular phosphotransferase activity catalytic activity intramolecular transferase activity	carbohydrate metabolic process primary metabolic process metabolic process cellular process monosaccharide metabolic process hexose metabolic process small molecule metabolic process glucose metabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR045244	Phosphoglucomutase	Family
A, B	IPR005846	Alpha-D-phosphohexomutase, alpha/beta/alpha domain III	Domain
A, B	IPR005845	Alpha-D-phosphohexomutase, alpha/beta/alpha domain II	Domain
A, B	IPR016055	Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III	Homologous Superfamily
A, B	IPR016066	Alpha-D-phosphohexomutase, conserved site	Conserved Site
A, B	IPR005844	Alpha-D-phosphohexomutase, alpha/beta/alpha domain I	Domain
A, B	IPR005841	Alpha-D-phosphohexomutase superfamily	Family
A, B	IPR036900	Alpha-D-phosphohexomutase, C-terminal domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.